Navigation Links
Pharmasset Announces the Expansion of the ELECTRON Trial in Chronic Hepatitis C
Date:6/8/2011

aluating 12-week regimens of PSI-7977 400mg QD in combination with ribavirin (RBV) only, and in separate arms with abbreviated durations of Peg-IFN for 4, 8, or 12 weeks in treatment-naive patients with HCV GT2 or GT3. The primary endpoint of the trial is the safety and tolerability of PSI-7977 400mg QD and RBV for 12 weeks, administered with or without Peg-IFN. On May 11, 2011, Pharmasset announced the completed enrollment of Part 1 of ELECTRON in patients with HCV GT 2 or GT 3:

  • PSI-7977 400mg with RBV for 12 weeks (no peginterferon);
  • PSI-7977 400mg with RBV for 12 weeks; Peg-IFN weeks 1-4 only;
  • PSI-7977 400mg with RBV for 12 weeks, Peg-IFN weeks 1-8 only;
  • PSI-7977 400mg with Peg-IFN and RBV for 12 weeks.

In Part 2 of ELECTRON, Pharmasset will enroll an additional 30 patients into exploratory regimens of monotherapy and abbreviated durations of total therapy.  Following on the first four Cohorts of ELECTRON a 5th cohort will be added to explore 7977 400mg monotherapy in treatment-naive patients with HCV GT2 or GT3:

  • PSI-7977 400mg monotherapy for 12 weeks.

With the previously reported 100% SVR12 in naive GT2/3 subjects in PROTON, a 6th and 7th cohort will be added to ELECTRON to explore shorter treatment durations in both GT2/3 naive subjects and HCV GT1 subjects who have documented null responses (less than 2 log(10) IU/mL reduction in HCV RNA after 12 weeks of Peg-IFN/RBV):

  • PSI-7977 400mg with Peg-IFN/RBV for 8 weeks
  • PSI-7977 400mg QD with Peg-IFN/RBV for 12 weeks.

About Pharmasset

Pharmasset is a clinical-stage pharmaceutical company committed to discovering, developing, and commercializing novel drugs to treat viral infections. Pharmasset's primary focus is the development of oral therapeutics for the treatment of hepatitis C virus
'/>"/>

SOURCE Pharmasset, Inc.
Copyright©2010 PR Newswire.
All rights reserved

Page: 1 2 3 4

Related medicine technology :

1. Pharmasset to Present at Two Upcoming Investor Conferences
2. Pharmasset Reports Fiscal Second Quarter 2011 Financial Results
3. Pharmasset Initiates Phase 2b ATOMIC Trial of PSI-7977 for Multiple HCV Genotypes
4. Pharmasset to Webcast an Investor Event From the EASL Meeting
5. Pharmasset to Present at Three Upcoming Investor Conferences
6. Pharmasset to Present at the Leerink Swann Hot Topics Roundtable Conference
7. Pharmasset Reports Fiscal First Quarter 2011 Financial Results
8. Pharmasset Announces Exercise of Underwriters Overallotment Option
9. Pharmasset Prices Public Offering of Common Stock
10. Pharmasset Announces Proposed Public Offering of Common Stock
11. Pharmasset Reports Positive Results from its HCV Clinical Programs
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/30/2014)... , N.J. and NEW BRUNSWICK, N.J., Sept. 30, 2014 /PRNewswire-USNewswire/ ... that allows Kessler Foundation and New Jersey Health ... research, education and patient care programs has been ... chief executive officer of Kessler Foundation and ... Health Foundation. "The experience of New ...
(Date:9/30/2014)... The Eastern European medical device industry is ... well as new medical-device manufacturers are constantly trying to ... ways to reduce the cost incurred for placing their ... the effective means to achieve this target. This research ... European and provides profiles of key distributors in ...
(Date:9/30/2014)... Passport Health, one of the largest immunizers ... FluFree.com, a website designed to promote, educate about, and ... years, Passport Health has provided its clients with protection ... FluFree.com is designed to address the growing gap between ... who actually chose to get vaccinated. "We ...
Breaking Medicine Technology:Kessler Foundation Partners with New Jersey Health Foundation To Start Innovative Companies To Change the Lives of People with Disabilities 2Medical Technologies Distributor Profiles in Eastern Europe 2Medical Technologies Distributor Profiles in Eastern Europe 3Passport Health Launches FluFree.com - Aims To Improve Flu Vaccination Rates and Fulfill Growing Public Health Priority 2Passport Health Launches FluFree.com - Aims To Improve Flu Vaccination Rates and Fulfill Growing Public Health Priority 3
... SUNNYVALE, Calif., May 22, 2012 Accuray ... premier radiation oncology company, announced today the signing ... with the German Cancer Research Center ... in Heidelberg, Germany. Accuray and DKFZ will collaborate ...
... CORDOVA, Calif., MAY 22, 2012 ThermoGenesis Corp. (NASDAQ: ... technologies for the processing, storage and administration of cell ... Thailand for its AXP® AutoXpress® Platform (AXP) used for ... expects to initiate commercial activities in the country later ...
Cached Medicine Technology:Accuray and the German Cancer Research Center Sign Master Research and Collaboration Agreement 2Accuray and the German Cancer Research Center Sign Master Research and Collaboration Agreement 3Accuray and the German Cancer Research Center Sign Master Research and Collaboration Agreement 4ThermoGenesis Announces Axp Approval In Thailand 2ThermoGenesis Announces Axp Approval In Thailand 3
(Date:9/30/2014)... Integrated Medicine Alliance , Monmouth County’s ... medical specialty practice through a unique partnership with an ... located within the company’s Shrewsbury location and will be ... of American Heart Center, P.C., a highly regarded practice ... Integrated Medicine Alliance patients top notch cardiovascular care without ...
(Date:9/30/2014)... leading cause of allergy-related sudden deaths in the U.S., ... to 2010, conducted by researchers at Montefiore ... Medicine of Yeshiva University . The study, published online ... Immunology , also found that the risk of fatal ... and African-Americans and that such deaths increased significantly in ...
(Date:9/30/2014)... EverStryke , the permanent match currently ... along with a free book and class all about survival ... prompting an investigative review. , “Joe Marshall of SurvivalLife.com ... and preparation niche, and this product is an excellent way ... survival products that Joe offers on his website to help ...
(Date:9/30/2014)... The American Diabetes Association touts ... their sweet tooth, but the most recent research, published ... that zero-calorie sweeteners may actually be linked to an ... Weizmann Institute of Science in Israel recently discovered ... the mice developed glucose intolerance. They then analyzed data ...
(Date:9/30/2014)... NY (PRWEB) September 30, 2014 ... hosted its annual “In Celebration” gala, honoring three ... nonprofit’s mission of striving to provide extraordinary and ... families facing a serious or life-limiting illness. , ... Club in Rye, NY and recognized William (Bill) ...
Breaking Medicine News(10 mins):Health News:Integrated Medicine Alliance Announces New Cardiology Practice 2Health News:Comprehensive Study of allergic deaths in US finds medications are main culprit 2Health News:EverStryke: Review Exposes Joe Marshall’s Permanent Match Survival Product 2Health News:Artificial Sweeteners May be Linked to Greater Diabetes Risk 2Health News:Hospice & Palliative Care of Westchester Honors Outstanding Individuals at Annual ‘In Celebration’ Gala 2
... initiative aimed at reducing preventable hospital errors and lowering costs, ... in-hospital falls. , Geriatricians were quick to point out that ... trying to keep elderly patients from falling, they said, it ... at all. And for the elderly, even a few ...
... students have been chosen as the newest participants in the ... The program is funded by the John A. Hartford ... , and directed by James Lubben , DSW, MPH. ... in matching support from his or her home institution, which ...
... , FRIDAY, Oct. 28 (HealthDay News) -- Trying ... bought for Halloween before the big night arrives? Worried that ... your child,s Halloween stash? Halloween doesn,t have to be ... coordinator for the Loyola Center for Fitness. Smith offered several ...
... shrinking population of trim Americans against an expanding population of ... "fat bans." These "fat policies" would be designed to ... the growth in Americans, waistlines and in the country,s healthcare ... the Land of the Free and the Home of ...
... dominated the research field in Alzheimer,s disease. The theory ... to the formation of plaques, toxic clusters of damaged ... at Lund University, Sweden, have now presented a study ... research group,s data offers an opposite hypothesis, suggesting that ...
... of life experienced by cancer survivors is becoming increasingly ... Such an assessment has a number of important applications when ... quality of life for cancer survivors is still being developed. ... be tailored through the use of measures specific to a ...
Cached Medicine News:Health News:Study finds no link between elderly patient activity and hospital falls 2Health News:Prestigious Hartford grants bolster awardees' social work research 2Health News:Prestigious Hartford grants bolster awardees' social work research 3Health News:Home of the free - land of the fat? 2Health News:New findings contradict dominant theory in Alzheimer's disease 2Health News:Cancer survivorship research must look at quality of life 2
... , Standby: A standby switch maintains power to ... 1 s (1 pulse/s) , Tetanus: 100 ... s) , Output Current: Adjustable from 0-70 mA ... (200-us duration) , Indicators: Battery LED (green) indicates ...
... A range of easy to use ... RDG nerve locator, peripheral nerve stimulator, and ... insulating pole, plastic hub, and pencil point ... an inexpensive, practical and easy to use ...
Based on the original MS-1 design the new MS-1B includes low battery detection, FET based output circuitry and enhanced battery compartment....
... for the delivery and monitoring of inhaled ... is a fully integrated, innovative instrument used ... therapy. The INOvent delivery system works in ... machine) to deliver a constant concentration of ...
Medicine Products: