Navigation Links
Pharmasset Announces Initiation of Combination Study of Clevudine and Viread(R) for HBV by French National Agency for Research on AIDS and Viral Hepatitis (ANRS)
Date:7/8/2008

table HBV DNA. These results were statistically significant compared to placebo. In addition to the potent antiviral suppression, 16% of the HBeAg- patients who received clevudine demonstrated a sustained virologic response (SVR) 24 weeks after stopping therapy, versus 0% of the patients who had received the placebo. In Study 303, a South Korean open-label, follow-on study of clevudine, Bukwang observed similar findings. 80% of HBeAg- patients had undetectable HBV DNA 12 weeks after completing a 48-week course of therapy.

Clevudine was generally safe and well-tolerated by patients with chronic HBV. There was no meaningful difference between clevudine and placebo in the incidence of serious adverse events during treatment in Studies 301 and 302 and during follow-up except that a higher percentage of placebo-treated patients had elevated liver enzyme levels than patients treated with clevudine.

About Pharmasset

Pharmasset is a clinical-stage pharmaceutical company committed to discovering, developing and commercializing novel drugs to treat viral infections. Pharmasset's primary focus is on the development of oral therapeutics for the treatment of hepatitis B virus (HBV), hepatitis C virus (HCV) and human immunodeficiency virus (HIV).

Pharmasset is currently developing three product candidates. Clevudine, for the treatment of chronic HBV infection, is in Phase 3 clinical trials for registration in the Americas and Europe. Clevudine is already approved for HBV in South Korea and marketed by Bukwang Pharmaceuticals in South Korea under the brand name Levovir. R7128, an oral treatment for chronic HCV infection, is in a Phase 1/2 clinical trial through a strategic collaboration with Roche. Racivir, which is being developed for the treatment of HIV in combination with other approved HIV drugs, has completed a Phase 2 clinical trial.

Contact

Kurt Leutzinger

Chief Financial Officer


SOURCE Pharmasset, Inc.
Copyright©2008 PR Newswire.
All rights reserved

Page: 1 2 3 4

Related medicine technology :

1. Pharmasset Receives Notice of Allowance
2. Pharmasset Nominates PSI-7851 as a Lead Development Candidate for the Treatment of Chronic Hepatitis C
3. Pharmasset Commences Dosing R7128 Cohorts 3 and 4 for the Treatment of Chronic Hepatitis C
4. Pharmasset Presents Results of 4-Week Combination Study of R7128 for the Treatment of Chronic Hepatitis C
5. Pharmasset Reports First Fiscal Quarter 2008 Financial Results
6. Roche and Pharmasset To Present the R7128 Monotherapy Resistance Profile
7. Pharmasset Announces R7128 Achieves 85% Rapid Virologic Response in a 4-week Combination Study for the Treatment of Chronic Hepatitis C
8. Pharmasset Announces Clevudine and R7128 Presentations at HEP-DART
9. Pharmasset Commences Dosing in 28-Day Combination Study of R7128 with Pegasys(R) plus Copegus(R) for Hepatitis C
10. Pharmasset Commences Dosing in Phase 3 Registration Studies of Clevudine for HBV
11. Pharmasset Presents R7128 Phase 1 Single Ascending Dose Study in Healthy Volunteers
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/29/2015)... , May 29, 2015 Educating ... of the Association for the Advancement of Wound ... With support from AAWC,s corporate partners, the ... Portal on the AAWC website at ... wound care pathway with links to various CME/CEU ...
(Date:5/28/2015)... Research and Markets ( ... Jain PharmaBiotech,s new report  "RNAi - Technologies, ...      (Logo: http://photos.prnewswire.com/prnh/20130307/600769) , , ... the use of double stranded RNA (dsRNA). ... processed into short 21-23 nucleotide RNAs termed ...
(Date:5/28/2015)... 28, 2015 The controversy surrounding the ... and myomectomies (procedures to remove uterine fibroids) continues, ... is investigating Johnson & Johnson,s Ethicon, Inc. unit, ... devices. According to the report published by The ... the FBI is trying to determine what the ...
Breaking Medicine Technology:The Association for the Advancement of Wound Care Educates the Public 2Global RNAi Market Report 2015-2024 - Technologies, Markets and Companies 2Global RNAi Market Report 2015-2024 - Technologies, Markets and Companies 3Power Morcellator Attorneys at Bernstein Liebhard LLP Comment on Report That FBI Is Investigating Ethicon Morcellators 2Power Morcellator Attorneys at Bernstein Liebhard LLP Comment on Report That FBI Is Investigating Ethicon Morcellators 3
... 8, 2010 A new analysis of the effects ... enhanced treatment options for tens of millions of people ... from certain food or nutritional supplements but not manufactured ... play a role in optimal brain functioning and have ...
... 7, 2010 Hop-on, Inc. (Pink Sheets: ... about the Appeals Court ruling that the Food and Drug ... of the Food, Drug and Cosmetic Act (according to ... in February 2010 when Federal Judge Leon ruled that the ...
Cached Medicine Technology:Omega-3 Supplements Show Promise in Alleviating Depression 2Hop-on Reports: FDA Cannot Regulate Electronic Cigarettes 2
(Date:5/29/2015)... 29, 2015 Red Hot & Blue ... Red Hot & Blue restaurant at 525 New Waverly Place ... 7, 2015. “The Red Hot & Blue Restaurant was previously ... but we have moved to a new location in the ... middle of all the activities on the Promenade–with outdoor seating ...
(Date:5/29/2015)... May 29, 2015 The Healthcare ... graduates of its Advanced Training Program (ATP) in ... fill roles in their health care organization ranging ... and methodology of continuous quality improvement in the ... to Dr. Brent James’ internationally recognized Advanced Training ...
(Date:5/29/2015)... Inspire Nexus, a new social network officially ... question many life coaches have asked, "How do I ... necessary to become a credentialed Coach?" , Many Life ... for long. Inspire Nexus, a social network for Coaches ... who have experience coaching a certain number of hours, ...
(Date:5/29/2015)... (PRWEB) May 29, 2015 The campaign ... well as a number of specific concerns within, including ... reduction and mental health in the workplace. We are ... health. The campaign also brings special focus to people ... to speak up and seek help from healthcare professionals ...
(Date:5/29/2015)... TX (PRWEB) May 29, 2015 ... 2015” provides comprehensive information on the therapeutic development ... types of muscles in the body, leading to ... R&D pipelines by identifying new targets and MOAs ... on H1 2015 pipeline review of Axillary Hyperhidrosis ...
Breaking Medicine News(10 mins):Health News:Red Hot & Blue Restaurant Opens in Cary, North Carolina 2Health News:Red Hot & Blue Restaurant Opens in Cary, North Carolina 3Health News:Red Hot & Blue Restaurant Opens in Cary, North Carolina 4Health News:HORNE LLP’s Healthcare Delivery Institute Graduates Class from the Advanced Training Program 2Health News:Mediaplanet Brings Activism to Those Living with Mental Illness in Bew “Mental Health Awareness” Campaign 2Health News:Muscle Spasm Therapeutic Development Pipeline Review H1 2015 Market Research Report Available at RnRMarketResearch.com 2Health News:Muscle Spasm Therapeutic Development Pipeline Review H1 2015 Market Research Report Available at RnRMarketResearch.com 3Health News:Muscle Spasm Therapeutic Development Pipeline Review H1 2015 Market Research Report Available at RnRMarketResearch.com 4
... , ALEXANDRIA, Va., July 17 ... a regular basis, and 40% of community-dwelling seniors take five or ... unemployment, many people are looking for ways to save on prescription ... for Medicines & Healthy Aging(C) (CMHA) -- a consumer-focused resource developed ...
... , Non and for profit collaborate during tough economic ... Nonprofits stressing over the sinking economy are thinking out of the ... companies are struggling much in the same way except that their funding ... & Family Health (ICFH) and Jungle Island decided to collaborate to attract ...
... ... with One Healthcare Solution,s EMR system in medical practices , ... Georgetown, TX (PRWEB) July 17, 2009 -- ... announced the signing of a Software Distribution Agreement along with an Additional Services Agreement ...
... The YAI/National ... at the law firm of Loeb & Loeb LLP, as Chair, and Sheldon Kwiat, President of ... ... Institute for People with Disabilities (YAI/NIPD) Board of Trustees has elected Eliot Green, a Partner ...
... ... a featured expert on searchbodydetox.com, a new informational Web site devoted to all aspects of ... ... of the alternative health movement, is now a featured expert on searchbodydetox.com , a ...
... how to pay for an overhaul of the nation,s health ... that including both private and public insurance choices in ... much as $265 billion in administrative costs from 2010 to ... budget costs of health care reform legislation under $1 trillion. ...
Cached Medicine News:Health News:Center for Medicines & Healthy Aging(C) and BidRx(R) Partner to Help Consumers Save on Prescription Medications 2Health News:Center for Medicines & Healthy Aging(C) and BidRx(R) Partner to Help Consumers Save on Prescription Medications 3Health News:Fundraising in the Jungle 2Health News:One Healthcare Solution and MedBeyond Partner to Provide Optimum Solution for EMR and Medical Billing 2Health News:One Healthcare Solution and MedBeyond Partner to Provide Optimum Solution for EMR and Medical Billing 3Health News:YAI/NIPD Board of Trustees Elects Eliot Green Chair and Sheldon Kwiat Vice Chair 2Health News:YAI/NIPD Board of Trustees Elects Eliot Green Chair and Sheldon Kwiat Vice Chair 3Health News:YAI/NIPD Board of Trustees Elects Eliot Green Chair and Sheldon Kwiat Vice Chair 4Health News:Dr. Julian Whitaker Featured on Searchbodydetox.com 2Health News:Private and public insurance choices could help pay for national health care reform 2Health News:Private and public insurance choices could help pay for national health care reform 3
... Antibodies (ANAs) has long been an important ... diseases. The antigens used in their detection ... human or animal nuclei, this has led ... (ENAs). The most commonly measured ENA specifications ...
Enzyme-linked immunosorbent assays for the detection and quantitation of IgG antibodies to extractable nuclear antigens (ENA) Sm in human serum.Antibodies to Sm aid in the diagnosis of systemic lupus...
... assays for the detection and ... extractable nuclear antigens (ENA) SS-B ... (Ro) and SS-B (La) antibodies ... SLE, subacute cutaneous lupus erythematosus ...
... assays for the detection and ... extractable nuclear antigens (ENA)RNP, Sm ... Sm aid in the diagnosis ... ,RNP antibodies aid in the ...
Medicine Products: