Navigation Links
Pharmasset Announces Initiation of Combination Study of Clevudine and Viread(R) for HBV by French National Agency for Research on AIDS and Viral Hepatitis (ANRS)
Date:7/8/2008

unique mechanism of action as a non-chain terminating nucleoside analog HBV polymerase inhibitor may demonstrate additive antiviral benefit in combination with tenofovir's recently demonstrated antiviral potency in HBV," stated Dr. Michelle Berrey, Pharmasset's Chief Medical Officer. "We also plan to reproduce the results from earlier studies demonstrating clevudine's ability to provide a sustained virologic response in patients with eAg negative chronic HBV infection, as either monotherapy or in combination, offering infected individuals and their physicians an important new treatment option."

Ongoing Registration Studies for New Drug Application (NDA)

The ongoing clevudine Phase 3 registration program includes two 48-week clinical trials designed to demonstrate the superiority of clevudine 30mg over Hepsera(R) (adefovir dipivoxil) 10mg, each administered once-daily as monotherapy. Pharmasset plans to submit the 48-week data from these studies to the FDA as the basis for the clevudine marketing approval. Please see http://www.clinicaltrials.gov or e-mail clinicaltrials@pharmasset.com for more information about the clevudine registration studies.

South Korean Registration Studies for Clevudine

Bukwang received marketing approval for clevudine from the South Korean FDA based on two 24-week, placebo-controlled, double-blind, randomized, multi-center South Korean Phase 3 registration trials in 337 patients. Study 301 enrolled 248 HBeAg+ patients who received clevudine 30 mg or a placebo once-daily, and Study 302 enrolled 89 HBeAg- patients who received clevudine 30 mg or a placebo once-daily. All patients were evaluated for an additional 24 weeks of follow-up care without clevudine treatment.

At 24 weeks on treatment with clevudine, 59% of HBeAg+ patients achieved undetectable HBV DNA and 92% of HBeAg- patients achieved undetec
'/>"/>

SOURCE Pharmasset, Inc.
Copyright©2008 PR Newswire.
All rights reserved

Page: 1 2 3 4

Related medicine technology :

1. Pharmasset Receives Notice of Allowance
2. Pharmasset Nominates PSI-7851 as a Lead Development Candidate for the Treatment of Chronic Hepatitis C
3. Pharmasset Commences Dosing R7128 Cohorts 3 and 4 for the Treatment of Chronic Hepatitis C
4. Pharmasset Presents Results of 4-Week Combination Study of R7128 for the Treatment of Chronic Hepatitis C
5. Pharmasset Reports First Fiscal Quarter 2008 Financial Results
6. Roche and Pharmasset To Present the R7128 Monotherapy Resistance Profile
7. Pharmasset Announces R7128 Achieves 85% Rapid Virologic Response in a 4-week Combination Study for the Treatment of Chronic Hepatitis C
8. Pharmasset Announces Clevudine and R7128 Presentations at HEP-DART
9. Pharmasset Commences Dosing in 28-Day Combination Study of R7128 with Pegasys(R) plus Copegus(R) for Hepatitis C
10. Pharmasset Commences Dosing in Phase 3 Registration Studies of Clevudine for HBV
11. Pharmasset Presents R7128 Phase 1 Single Ascending Dose Study in Healthy Volunteers
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/19/2014)... , Sept. 19, 2014  Diplomat, the nation,s largest ... David Dreyer to the Board of Directors on ... and will also serve as chair of the Audit ... years of accounting, financial, compliance and operating experience in ... has served as chief financial officer, chief operating officer ...
(Date:9/19/2014)... WOONSOCKET, R.I. , Sept. 19, 2014 Five MinuteClinic ... Memphis metropolitan area. Three clinics opened in ... earlier this month. A fourth clinic will be added in ... in Bartlett is expected to open October ... medical clinics in the United States . ...
(Date:9/19/2014)... According to market research ... Industrial, & Laboratory), Industry (Food, Pharmaceutical, Biotechnology, Surgical ... & Geography - Global Trends & Forecast to ... lyophilization market on the basis of various types, ... the market size of each of these segments ...
Breaking Medicine Technology:David Dreyer Appointed to Diplomat Board of Directors 2MinuteClinic Walk-in Medical Clinics Opening in Memphis 2MinuteClinic Walk-in Medical Clinics Opening in Memphis 3Lyophilization Market Worth $5,121.5 Million by 2019 2Lyophilization Market Worth $5,121.5 Million by 2019 3
... Inc., (Ticker: AVTC) ( www.autoretail.com ), is a leading ... for use in hospitals, pharmacies, medical offices and clinics. ... reduce and even eliminate prescription medicine dispensing errors.   ... of Pharmacy Practice reviewed 60 research papers that analyzed ...
... of reusable medical device cleaning validations, resulting from the U.S. ... CFR 610 , is discussed in a new management brief ... . The FDA,s proposed amendments to 21 CFR ... Register on June 21, 2011, for review and comment, ...
Cached Medicine Technology:Automated Medicine Dispensing Units Developed by AVT Can Reduce Errors 2Summary of Proposed Changes to 21 CFR 610 is Detailed in New Management Brief from Microtest Laboratories 2
(Date:9/21/2014)... 2014 Expert witness work is in! ... from its 2014 Expert Witness Fees & Practices Survey. ... demand and compensation for qualified and credentialed expert witnesses ... 16-year history. , The nearly 600 experts surveyed ... expert work, an increase of 3.2% from ExpertPages’ 2012 ...
(Date:9/21/2014)... "I wanted to be able to obtain ... foul-tasting energy drinks," said an inventor from Fresh Meadows, ... drink plain, old coffee. That is why I came ... ENERG CHEWING GUM to provide a healthy energy boost ... contains nutritious vitamins, minerals and antioxidants. It also features ...
(Date:9/21/2014)... September 21, 2014 "I want to ... and back but haven’t the money for chiropractors," said ... to have such a product for myself." , The ... to stretch the thigh muscles and align the spine ... as relieves discomfort of pinched nerves. Compact and easy ...
(Date:9/21/2014)... (PRWEB) September 21, 2014 Best Cheap ... recently announced that Arvixe, Bluehost and GreenGeeks are the ... to find a good reseller hosting supplier. Actually, these ... server speed and customer support. People can get the ... manager says. , According to the manager, reseller ...
(Date:9/21/2014)... To accommodate the ever-growing customer base, Angeldress.co.uk decided ... items. Recently, the company has unveiled its 2014 ... elegant wedding gowns, Angeldress.co.uk wants to make sure that ... easy way. Its high quality vintage wedding outfits are ... to 62% off. , Online shopping is becoming more ...
Breaking Medicine News(10 mins):Health News:ExpertPages 2014 Survey Reports Expert Witness Hourly Fees Record All-Time Highs as Demand for Qualified Experts Continues to Grow 2Health News:Best Cheap Hosting USA Announces The Best Reseller Hosting Suppliers In 2014 2Health News:Angeldress.co.uk Launches New Range Of 2014 Vintage Wedding Dresses In Its Online Store 2
... Nov. 17 Shopko Stores Operating Co., LLC announced the ... www.shopko.com . Shopko partnered with SpeedFC, a ... advance the Company,s online selling initiatives. , The new online ... in apparel, home, accessories, gift cards and more. The site ...
... is one of 12 sites nationwide participating in the ... treatment for Alzheimer,s disease. The study is the first ... The experimental treatment utilizes a viral-based gene transfer ... naturally occurring protein that helps maintain nerve cell survival ...
... a new model of comprehensive health care for people ... Economics Award for Innovation in Practice Improvement from the ... Teachers of Family Medicine (STFM) and Medical Economics magazine. ... the Guided Care study and director of the Roger ...
... Hughes Medical Institute (HHMI) today committed four years, ... program between Rice University and the University of ... program -- founded with a 2006 HHMI grant ... bioengineering program and M.D. Anderson,s internationally renowned clinical ...
... ... successfully blended custom EDM machining and lights-out automation for greater speed and accuracy for ... are critical to optimized performance. , ... Tucker, GA (PRWEB) November 17, 2009 -- A proprietary new technology ...
... might help reduce heart attacks, researchers say , ... soybeans boosts levels of an important omega-3 fatty acid in ... U.S. researchers say. , They created soybeans that produce oils ... body into an omega-3 fatty acid called eicosapentaenoic acid (EPA). ...
Cached Medicine News:Health News:Shopko Announces Launch of e-Commerce Platform 2Health News:Mount Sinai researchers to test first gene therapy For Alzheimer's patients 2Health News:'Guided Care' receives Award for Innovation in Practice Improvement 2Health News:New funds for Rice, M.D. Anderson program 2Health News:Proprietary EDM Machining Technology Boosts Speed and Accuracy for Medical Components 2Health News:Biotech Soybeans Good Source of Omega-3 2
... Axiovert 40 inverted ... you have ever expected from a microscope in ... outstanding quality, and functionality. Axiovert 40 has been ... safe as possible thus increasing the efficiency ...
... is an advanced inverted microscope ... exclusive CFI60 optical system, extendible ... it ideal for high precision, ... inverted microscope to take full ...
... Eclipse TE2000E is an advanced inverted microscope ... five imaging ports, high resolution CFI60 optics, ... perfect imaging workstation. In addition, its super-nanoprecision ... control is perfect for precise imaging in ...
... The IX71's modular frame ... 9 access ports for ... devices. Up to four ... access to a primary ...
Medicine Products: