Navigation Links
Pharmasset Announces Initiation of Combination Study of Clevudine and Viread(R) for HBV by French National Agency for Research on AIDS and Viral Hepatitis (ANRS)
Date:7/8/2008

96-week comparative study of Clevudine versus Viread(R) versus

Clevudine+Viread(R) in 150 patients with chronic hepatitis B

PRINCETON, N.J., July 8 /PRNewswire-FirstCall/ -- The French National Agency for Research on AIDS and Viral Hepatitis (ANRS), with the support of Pharmasset, Inc. (Nasdaq: VRUS) and Gilead Sciences, Inc. (Nasdaq: GILD), has initiated the first head-to-head study of clevudine and Viread(R) (tenofovir disoproxil fumarate) administered separately, versus their combination, for the treatment of chronic hepatitis B virus (HBV) infection in non-cirrhotic patients. The study treatments include clevudine 30mg/day, tenofovir 300mg/day or the combination of both drugs administered to 150 treatment-naive hepatitis B e-antigen negative HBV-infected patients for 96 weeks. At that time, all therapy will be discontinued, and patients will be monitored for sustained virologic response (SVR) after being off of therapy for 24 weeks, the primary endpoint of the study.

Clevudine is an oral, once-daily pyrimidine nucleoside analog that has been evaluated in 18 clinical trials in more than 800 individuals. Phase 3 studies are currently being conducted in approximately 140 global clinical sites to support the registration of clevudine in the Americas and Europe. Pharmasset licensed clevudine for these territories from Bukwang Pharm. Co., Ltd, who has received South Korean regulatory approval and is currently marketing clevudine in South Korea under the brand name Levovir.

"Clevudine's
'/>"/>

SOURCE Pharmasset, Inc.
Copyright©2008 PR Newswire.
All rights reserved

0

GOOD

Page: 1 2 3 4

Related medicine technology :

1. Pharmasset Receives Notice of Allowance
2. Pharmasset Nominates PSI-7851 as a Lead Development Candidate for the Treatment of Chronic Hepatitis C
3. Pharmasset Commences Dosing R7128 Cohorts 3 and 4 for the Treatment of Chronic Hepatitis C
4. Pharmasset Presents Results of 4-Week Combination Study of R7128 for the Treatment of Chronic Hepatitis C
5. Pharmasset Reports First Fiscal Quarter 2008 Financial Results
6. Roche and Pharmasset To Present the R7128 Monotherapy Resistance Profile
7. Pharmasset Announces R7128 Achieves 85% Rapid Virologic Response in a 4-week Combination Study for the Treatment of Chronic Hepatitis C
8. Pharmasset Announces Clevudine and R7128 Presentations at HEP-DART
9. Pharmasset Commences Dosing in 28-Day Combination Study of R7128 with Pegasys(R) plus Copegus(R) for Hepatitis C
10. Pharmasset Commences Dosing in Phase 3 Registration Studies of Clevudine for HBV
11. Pharmasset Presents R7128 Phase 1 Single Ascending Dose Study in Healthy Volunteers
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/1/2008)...swire/ -- New research has found that the availabi... (CT) scanner in an emergency room can significant...ve a potentially life-saving treatment. Results of...r (NSMC)-Salem Hospital in Salem, Mass., will be p...ogical Society of North America (RSNA). , , ...
(Date:12/1/2008)... A study has found that...que for imaging the breast, is not affected by eit...wo factors that limit the effectiveness of standar... will be presented today at the annual meeting of ... , , "The ability of PEM to detect cancer d...
(Date:12/1/2008)...e-FirstCall/ -- Vanda Pharmaceuticals Inc. (Nasdaq...e of the world,s leading medical journals, results...or, experimental compound tasimelteon (VEC-162). ... "Melatonin agonist tasimelteon (VEC-162) for tran...sed controlled multicentre trials." Results are re...
(Date:12/1/2008)... TargeGen has announced that an oral,presentation...ased clinical,trial of TG101348 in myeloprolifera...008 American Society of Hematology (ASH) Meeting. ...ows:, Title: A Phase I Study of... JAK2-Selective Inhibitor, in Patients wit...
Breaking Medicine Technology:Portable CT Increases Chance of Stroke Survival and Recovery 2Portable CT Increases Chance of Stroke Survival and Recovery 3New Mammography Technology Effective in Detecting Breast Cancer 2New Mammography Technology Effective in Detecting Breast Cancer 3New Mammography Technology Effective in Detecting Breast Cancer 4Clinical Trial Results on the Sleep-Promoting Effects of Vanda Pharmaceuticals' Circadian Regulator Tasimelteon (VEC-162) Published in The Lancet 2Clinical Trial Results on the Sleep-Promoting Effects of Vanda Pharmaceuticals' Circadian Regulator Tasimelteon (VEC-162) Published in The Lancet 3Clinical Trial Results on the Sleep-Promoting Effects of Vanda Pharmaceuticals' Circadian Regulator Tasimelteon (VEC-162) Published in The Lancet 4Governors Task Force Cites PAs 2436 5 Billion Water Infrastructure Need 3B Report Underscores Call for Additional Investments 28454 1Governors Task Force Cites PAs 2436 5 Billion Water Infrastructure Need 3B Report Underscores Call for Additional Investments 28454 2Governors Task Force Cites PAs 2436 5 Billion Water Infrastructure Need 3B Report Underscores Call for Additional Investments 28454 3Turning Clocks Back Increases Risk of Drowsy Driving 28449 1Turning Clocks Back Increases Risk of Drowsy Driving 28449 2Nutrition 21 to Report Preliminary First Quarter Fiscal Year 2009 Financial Results on Thursday November 13 2008 28446 1Nutrition 21 to Report Preliminary First Quarter Fiscal Year 2009 Financial Results on Thursday November 13 2008 28446 2FDA Warns of Dangers of Mexican Vanilla 28441 1
...hase 2 BPD Clinical Data Selected and Presented as...lis Aerosol-Generator Technology,Demonstrates Opti...2007 (PRIME NEWSWIRE) -- Discovery,Laboratories, I...previously completed Phase 2 clinical trial of Sur...r the prevention and,treatment of Bronchopulmonary...
...ieves Primary Endpoint Among High-Risk Infants Ver...f Medically Attended,Outpatient RSV- Related Lower...PRNewswire-FirstCall/ -- MedImmune, Inc.,today ann...rial,conducted for prevention of respiratory syncy...the investigational monoclonal antibody,(MAb) also...
Other Medicine Technology:Discovery Labs Presents Surfaxin and Aerosurf Data At the Pediatric,Academic Societies' Annual Meeting 2Discovery Labs Presents Surfaxin and Aerosurf Data At the Pediatric,Academic Societies' Annual Meeting 3Discovery Labs Presents Surfaxin and Aerosurf Data At the Pediatric,Academic Societies' Annual Meeting 4Discovery Labs Presents Surfaxin and Aerosurf Data At the Pediatric,Academic Societies' Annual Meeting 5Discovery Labs Presents Surfaxin and Aerosurf Data At the Pediatric,Academic Societies' Annual Meeting 6Discovery Labs Presents Surfaxin and Aerosurf Data At the Pediatric,Academic Societies' Annual Meeting 7MedImmune Announces Positive Clinical Results at PAS Annual Meeting,From Large Prospective Trial in Prevention of Serious RSV Disease 2MedImmune Announces Positive Clinical Results at PAS Annual Meeting,From Large Prospective Trial in Prevention of Serious RSV Disease 3MedImmune Announces Positive Clinical Results at PAS Annual Meeting,From Large Prospective Trial in Prevention of Serious RSV Disease 4MedImmune Announces Positive Clinical Results at PAS Annual Meeting,From Large Prospective Trial in Prevention of Serious RSV Disease 5MedImmune Announces Positive Clinical Results at PAS Annual Meeting,From Large Prospective Trial in Prevention of Serious RSV Disease 6MedImmune Announces Positive Clinical Results at PAS Annual Meeting,From Large Prospective Trial in Prevention of Serious RSV Disease 7
(Date:12/2/2008)... Dec. 2 Population Serv...hensive project that could dramatically reduce the...malaria. The program will provide free artemisinin...community health workers to poor children suspecte...to treatment will be monitored to determine if it ...
(Date:12/1/2008)... CHICAGO, Dec. 2 Includ...y enable a more meticulous reading from the radiol...ersonal and empathetic approach, according to a st...adiological Society of North America (RSNA). , ...nt as a human being and not as an anonymous case s...
(Date:12/1/2008)... Ind., Dec. 2 Patient satisfaction...on the rise according to a new report,from Press ...Report: Patient,Perspectives on American Health C...as a driver for improvement in patient services. ...llion patients treated at more than,1,200 outpati...
(Date:12/1/2008)...c. 2 New research revea...o known as virtual colonoscopy, has the potential ...cer and osteoporosis, both of which commonly affec... presented today at the annual meeting of the Radi..., "With CT colonography, in addition to screenin...
Breaking Medicine News(10 mins):Health News:Canada Supports Ground-Breaking Malaria Treatment Program in Sub-Saharan Africa 2Health News:Canada Supports Ground-Breaking Malaria Treatment Program in Sub-Saharan Africa 3Health News:Patient Photos Spur Radiologist Empathy and Eye for Detail 2Health News:Patient Photos Spur Radiologist Empathy and Eye for Detail 3Health News:Outpatient Service Facilities Face Increasing Competition - Patient Perceptions More Important Than Ever 2Health News:CT Colonography Offers One-Stop Screening for Cancer and Osteoporosis 2Health News:CT Colonography Offers One-Stop Screening for Cancer and Osteoporosis 3
...new research, oxygen therapy at home reduces hospi... at the University Hospital of Denmark, have studi...er's lungs// - where the blood becomes deficient i... an outpatient clinic, then continued at home. Ha...
...e been studying about the outcome of the hitech sc... glucose uptake in a tumour shows who has a poor p...cts mainly younger people. //It's an unusual cance... unpredictable. Researchers at the University of G...
...s have found out that people under age 48 who suff...their healthy peers to have a defect in a gene cal...) combat the damaging effects of LDL (the bad chol... people, stroke is not a rare event in younger ind...
...cent study, a simple imaging test may identify pat...ally fatal heart condition. Researchers used Doppl...diagnose hypertrophic cardiomyopathy earlier in a ...CM) causes thickening of the left ventricle of the...
Other Medicine News:
For the qualitative detection of human Chorionic Gonadotrophin (hCG) in urine specimens
For the qualitative detection of human Chorionic Gonadotrophin (HCG) in urine or urine and serum specimens
For the qualitative detection of single and multiple drugs and drug metabolites in human urine
For the qualitative detection of single and multiple drugs and drug metabolites in human urine
Medicine Products: