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Pharmacyclics Announces Oral Presentations and Clinical Update at Upcoming Medical Meetings
Date:5/18/2011

SUNNYVALE, Calif., May 18, 2011 /PRNewswire/ -- Pharmacyclics, Inc. (NASDAQ: PCYC) today announced that a clinical abstract on our Btk inhibitor, PCI-32765, has been selected for an oral presentation at the 47th Annual Meeting of the American Society of Clinical Oncology (ASCO), June 3-7, 2011 in Chicago, IL. Additionally, two clinical abstracts on PCI-32765 have been selected for oral presentations at the 11th International Conference on Malignant Lymphoma (ICML) in Lugano, Switzerland, June 15-18, 2011.

Pharmacyclics plans to present a material update on the PCI-32765 clinical development program in a press release after the ASCO oral presentation on Monday, June 6, 2011 and expects to hold a conference call as well. The update will encompass the entire PCI-32765 clinical development program and will specifically include: 1) safety and efficacy data with the use of single-agent PCI-32765 in relapsed/ refractory or treatment-naive chronic lymphocytic leukemia/small cell lymphocytic lymphoma (CLL/SLL) in patients with adequate follow-up from our ongoing Phase IB/II trial, including patients with poor-risk disease; 2) an update of efficacy from the Phase 1A trial of PCI-32765 in B-cell malignancies, including mantle cell lymphoma, follicular lymphoma and diffuse large B-cell lymphoma and 3) a status update for ongoing PCI-32765 clinical studies, including  a pilot trial of PCI-32765 in the ABC subtype of diffuse large B-cell lymphoma, a phase II trial of single agent PCI-32765 in mantle cell lymphoma, and studies with PCI-32765 in combination with either bendamustine/rituximab (BR), fludarabine/cyclophosphamide/rituximab (FCR), or ofatumumab in CLL. Oral Abstract Data Presentation at ASCO, Chicago (June 3 – 7, 2011)Abstract #6508Title: Activity and tolerability of the Bruton's tyrosine kinase (Btk) inhibitor PCI-32765 in patients with chronic lymphocytic leukemia/sm
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