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PharmaPoint: Multiple Sclerosis - United Kingdom Drug Forecast and Market Analysis to 2022
Date:5/16/2013

matic Therapies 274.3 United Kingdom 284.3.1 Diagnosis 284.3.2 Clinical Practice 285 Competitive Assessment 305.1 Overview 305.2 Strategic Competitor Assessment 315.3 Product Profiles – Major Brands 335.3.1 Betaseron/Betaferon (interferon beta-1b) 335.3.2 Avonex (interferon beta-1a) 385.3.3 Rebif (interferon beta-1a) 435.3.4 Copaxone (glatiramer acetate; copolymer-1) 475.3.5 Tysabri (natalizumab) 515.3.6 Gilenya/Imusera (fingolimod; FTY720) 565.3.7 Aubagio (teriflunomide) 615.3.8 Other Disease–Modifying Therapies 666 Opportunity and Unmet Need 676.1 Overview 676.2 Unmet Needs 686.2.1 Currently Available MS Drugs Only Provide Partial Benefits 686.2.2 The High Cost of MS Drugs Could Continue to Price out Patients 696.2.3 Safety and Tolerability of Therapy is Undermined by Side Effects 706.2.4 Effective Treatments for Progressive MS Are Still Elusive 716.2.5 Inconvenient Route of Administration and Frequent Dosing Limits Compliance 726.2.6 The Lack of Predictive Biomarkers Delays MS Diagnosis 736.3 Unmet Needs Gap Analysis 746.4 Opportunities 756.4.1 Treatments for Progressive MS 756.4.2 Targeting Patients with Clinically Isolated Syndrome 757 Pipeline Assessment 767.1 Overview 767.2 Promising Drugs in Clinical Development 787.2.1 BG-12 (dimethyl fumarate; BG00012) 807.2.2 Lemtrada (alemtuzumab) 857.2.3 Laquinimod (ABR-215062) 917.2.4 Daclizumab High-Yield Process (HYP) 967.2.5 Ocrelizumab (RG1594) 1017.2.6 Siponimod (BAF-312) 1067.2.7 NU-100 (interferon beta-1b) 1107.2.8 Masitinib (AB-1010) 1147.2.9 Tcelna (imilecleucel-T) 1188 Market Outlook 1228.1 United Kingdom 1228.1.1 Forecast 1228.1.2 Key Events 1268.1.3 Drivers and Barriers 1279 Appendix 1299.1 Bibliography 1299.2 Abbreviations 1409.3 Methodology 1449.4 Forecasting Methodology 1449.4.1 Diagnosed MS patients 1449.4.2 Percent Drug-Treated Patients 1459.4.3 Drugs Included in Each Therapeutic Class 1459.4.4 Launch and Pat
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