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PharmaPoint: Multiple Sclerosis - US Drug Forecast and Market Analysis to 2022
Date:5/14/2013

Analysis, 2012 66Table 22: Summary of Alternative MS DMTs, 2012 67Table 23: Overall Unmet Needs – Current Level of Attainment 68Table 24: Clinical Unmet Needs – Gap Analysis, 2012 75Table 25: Multiple Sclerosis – Phase Pipeline, 2012 78Table 26: Comparison of Therapeutic Classes in Development for Multiple Sclerosis, 2012 80Table 27: Product Profile – BG-12 82Table 28: BG-12 SWOT Analysis, 2012 85Table 29: Product Profile – Lemtrada 87Table 30: Lemtrada SWOT Analysis, 2012 91Table 31: Product Profile – Laquinimod 93Table 32: Laquinimod SWOT Analysis, 2012 96Table 33: Product Profile – Daclizumab High-Yield Process 97Table 34: Daclizumab SWOT Analysis, 2012 101Table 35: Product Profile – Ocrelizumab 103Table 36: Ocrelizumab SWOT Analysis, 2012 106Table 37: Product Profile – Siponimod 107Table 38: Siponimod SWOT Analysis, 2012 110Table 39: Product Profile – NU-100 112Table 40: NU-100 SWOT Analysis, 2012 114Table 41: Product Profile – Masitinib 115Table 42: Masitinib SWOT Analysis, 2012 118Table 43: Product Profile – Tcelna 120Table 44: Tcelna SWOT Analysis, 2012 122Table 45: Sales Forecasts ($m) for Multiple Sclerosis in the United States, 2012-2022 125Table 46: Key Events Impacting Sales for Multiple Sclerosis the United States, 2012 127Table 47: Multiple Sclerosis Market in the United States – Drivers and Barriers, 2012 128Table 48: Key Launch Dates 147Table 49: Key Patent Expiries 147Table 50: Physicians Surveyed, By Country 155

List of Figures

Figure 1: Accrual of Disability in the Four Subtypes of Multiple Sclerosis 16Figure 2: Expanded Disability Status Scale (EDSS) 22Figure 3: Current Algorithm for the Treatment of MS with Disease-Modifying Therapies 26Figure 4: Competitive Assessment of Late-Stage Pipeline Agents in Multiple Sclerosis, 2012–2022 79Figure 5: Sales for Multiple Sclerosis in the United
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