Navigation Links
PharmaFocus: Vaccine Adjuvants in Infectious Disease
Date:4/11/2013

/p>

Table 2: Immune Cells and Their Corresponding Toll-like Receptors 15

Table 3: TLR Adjuvant Targets and Ligand Types in Clinical Trials for Infectious Disease Vaccines 24

Table 4: Vaccine Adjuvants – Drivers and Barriers, 2013 27

Table 5: Leading Adjuvants in Clinical Trials for Human Infectious Disease Vaccines 36

Table 6: Product Profile – Aluminum Salts/Alum 38

Table 7: Aluminum Salts/Alum SWOT Analysis, 2013 40

Table 8: Product Profile – Emulsions 42

Table 9: Emulsions SWOT Analysis, 2013 43

Table 10: Product Profile – Particulate Delivery Mechanisms 45

Table 11: Particulate Delivery Mechanisms SWOT Analysis, 2013 46

Table 12: Product Profile – Microbial Derivatives 48

Table 13: Microbial Derivatives SWOT Analysis, 2013 49

Table 14: Product Profile – Oligonucleotides 50

Table 15: Oligonucleotides SWOT Analysis, 2013 52

Table 16: Product Profile – Adjuvant Systems 53

Table 17: GSK's Adjuvant System Portfolio, 2013 53

Table 18: Adjuvant Systems SWOT Analysis, 2013 55

Table 19: Overall Unmet Needs – Current Level of Attainment 56

Table 20: Regulatory Guidelines for the Approval of Adjuvanted Vaccines 72

List of Figures Figure 1: Immune System – Stimulation of Innate and Adaptive Responses 13

Figure 2: Adjuvant Targets – Human Toll-like Receptor Family 23

Figure 3: Adjuvant – Host Immune Response Interactions 35

Figure 4: Chemical Structure of MPL 47

Figure 5: Chemical Structure of Dinitrophenylated CpG ODN 50

Figure 6: WHO Map to Vaccine Adjuvant Usage 69

To order this report:Drug_and_Medication Industry:

SOURCE Reportlinker
Copyright©2012 PR Newswire.
All rights reserved

Page: 1 2 3 4 5

Related medicine technology :

1. Army Researcher Develops Potential Vaccine Carrier That May Give Stockpiling Efforts A Shot In The Arm
2. Shingles Vaccine is Safe, According to New Study
3. Soligenix Announces Further Progress with ThermoVax™ for Long-Term Vaccine ThermoStability
4. Inovio Pharmaceuticals Granted U.S. Patent Protection for Synthetic Vaccine for Cervical Dysplasia and Cancer
5. Biomedical Advanced Research and Development Authority (BARDA) Exercises Option with Pfenex Inc. To Extend Contract for the Development of a Recombinant Protective Antigen (rPA) Based Anthrax Vaccine
6. Sanofi Pasteur Presents Pediatric Data on Investigational Quadrivalent Influenza Vaccine
7. Generex Announces Presentations of Antigen Express AE37 Breast Cancer Vaccine Data at ASCO 2012
8. Inovio Pharmaceuticals Universal Avian Flu Vaccine Generates Protective Antibody Responses Against Six H5N1 Viruses in Phase I Trial
9. Global Human Vaccines Industry
10. Generex Announces New Members of Antigen Express Scientific Advisory Board for the AE37 Breast Cancer Vaccine
11. HIV Vaccine Trials Network Opens Enrollment for Phase 1 Trial of GeoVax Labs Second Generation HIV Vaccine
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/24/2014)... /PRNewswire-iReach/ -- "North America Orthopedic Braces and Supports Market ... North America Orthopedic Braces and Supports market. The report ... (in units) and average price data (in US dollars), ... Supports , Ankle Braces and Supports , ... and Supports. Photo - ...
(Date:7/24/2014)... -- Questcor Pharmaceuticals, Inc. (NASDAQ: QCOR ) today ... 2014. Three Months Ended 06/30/14Three Months Ended 06/30/13 ,  Percentage ... 51% Non-GAAP Net Sales , $278.8 Million , $196.1 ... , $1.12 , 37% Non-GAAP Diluted ... 37%  Six Months Ended 06/30/14Six Months Ended 06/30/13 , ...
(Date:7/24/2014)... 24, 2014  To help health care organizations ... could impact patient care and the bottom line, ... , "Innovations in Cardiovascular Devices."  ... and details on promising new technologies that can ... how these options impact the supply chain.   According ...
Breaking Medicine Technology:North America Orthopedic Braces and Supports Market (Knee, Ankle & Spinal Braces) to 2020 2North America Orthopedic Braces and Supports Market (Knee, Ankle & Spinal Braces) to 2020 3North America Orthopedic Braces and Supports Market (Knee, Ankle & Spinal Braces) to 2020 4North America Orthopedic Braces and Supports Market (Knee, Ankle & Spinal Braces) to 2020 5Questcor Reports Record Second Quarter Financial Results 2Questcor Reports Record Second Quarter Financial Results 3Questcor Reports Record Second Quarter Financial Results 4Questcor Reports Record Second Quarter Financial Results 5Questcor Reports Record Second Quarter Financial Results 6Questcor Reports Record Second Quarter Financial Results 7Questcor Reports Record Second Quarter Financial Results 8Questcor Reports Record Second Quarter Financial Results 9Questcor Reports Record Second Quarter Financial Results 10Questcor Reports Record Second Quarter Financial Results 11Questcor Reports Record Second Quarter Financial Results 12Questcor Reports Record Second Quarter Financial Results 13Questcor Reports Record Second Quarter Financial Results 14Questcor Reports Record Second Quarter Financial Results 15Questcor Reports Record Second Quarter Financial Results 16Questcor Reports Record Second Quarter Financial Results 17Questcor Reports Record Second Quarter Financial Results 18Questcor Reports Record Second Quarter Financial Results 19Questcor Reports Record Second Quarter Financial Results 20Questcor Reports Record Second Quarter Financial Results 21Questcor Reports Record Second Quarter Financial Results 22Questcor Reports Record Second Quarter Financial Results 23Questcor Reports Record Second Quarter Financial Results 24Questcor Reports Record Second Quarter Financial Results 25Questcor Reports Record Second Quarter Financial Results 26Questcor Reports Record Second Quarter Financial Results 27Questcor Reports Record Second Quarter Financial Results 28New Novation CV Watch Shows Recent Technology Innovations Could Drive Cardiovascular Product Costs Up by as Much as 35 Percent 2New Novation CV Watch Shows Recent Technology Innovations Could Drive Cardiovascular Product Costs Up by as Much as 35 Percent 3
...  TSH testing, the gold standard in hypothyroid diagnosis, may ... new article titled Hormone Replacement Therapy in ... Questions for the Future. Estrogen, Progesterone, Testosterone, and Thyroid ... article, independently written and published, is a broad study ...
... Jan. 2, 2012 Regeneron Pharmaceuticals, Inc. (NASDAQ: ... call on Tuesday, January 3, 2012 at 8:30 a.m. Eastern ... ongoing patent litigation with Genentech, Inc., a member of the ... Conference Call InformationDomestic Dial-in Number: (888) 660-6127 International Dial-in Number: ...
Cached Medicine Technology:Studies Show That TSH Is Unreliable in the Diagnosis of Hypothyroidism According to Article Contributed by Kent Holtorf, M.D. in Clinical Geriatrics 2Regeneron to Host Conference Call on January 3 at 8:30 a.m. Eastern Time to Discuss Ongoing Patent Litigation 2
(Date:7/24/2014)... (PRWEB) July 24, 2014 In ... Tuesday, President Obama cited the Atlanta BeltLine Workforce ... programs from across the country ( http://www.whitehouse.gov/ready-to-work ... an essential pillar of U.S. economic strategy and ... , “This recognition from President Obama highlights the ...
(Date:7/24/2014)... University, working with high-throughput data generated by breast ... devised a computational method to determine how gene ... malignant and as they respond to potential cancer ... interact with each other in laboratory-grown cells is ... online journal PLOS Computational Biology . , ...
(Date:7/24/2014)... rare procedure occasionally performed during Jewish circumcisions that involves ... herpes simplex virus type 1 (HSV-1) transmissions documented in ... conducted by Penn Medicine researchers and published online ... Society found. The reviewers, from Penn,s ... in New York, Canada and Israel. , The practiceknown ...
(Date:7/24/2014)... Lynn E. Taylor, M.D., director of The ... the July, 2014 Rhode Island Medical Journal ... eliminating hepatitis c virus infection (hep c or ... capacity to address other health challenges, and improve ... the United States, Taylor says, include lack of ...
(Date:7/24/2014)... July 24, 2014 Plaintiffs in ... ) against the manufacturer of Delatestryl, alleging they ... with the low testosterone injection, Bernstein Liebhard LLP ... in the Ontario Superior Court of Justice on ... low testosterone therapy is associated with an increased ...
Breaking Medicine News(10 mins):Health News:President Cites Atlanta BeltLine Workforce Partnership in Healthcare as National Model 2Health News:President Cites Atlanta BeltLine Workforce Partnership in Healthcare as National Model 3Health News:President Cites Atlanta BeltLine Workforce Partnership in Healthcare as National Model 4Health News:President Cites Atlanta BeltLine Workforce Partnership in Healthcare as National Model 5Health News:Gene changes in breast cancer cells pinpointed with new computational method 2Health News:Gene changes in breast cancer cells pinpointed with new computational method 3Health News:Link between ritual circumcision procedure and herpes infection in infants examined 2Health News:Miriam Hospital physician advocates awareness, collaboration to combat peaking hep C virus 2Health News:Miriam Hospital physician advocates awareness, collaboration to combat peaking hep C virus 3Health News:Miriam Hospital physician advocates awareness, collaboration to combat peaking hep C virus 4Health News:Testosterone Lawsuit News: Canadian Plaintiffs File Class Action Lawsuit Against Manufacturer of Delatestryl Testosterone Injection, Bernstein Liebhard LLP Reports 2Health News:Testosterone Lawsuit News: Canadian Plaintiffs File Class Action Lawsuit Against Manufacturer of Delatestryl Testosterone Injection, Bernstein Liebhard LLP Reports 3
... System in U.S. receives a low score (66 out ... first national scoring system of the 18-member Commonwealth Fund ... in promoting better health care systems for low-income and ... rankings were based on the scoring in various areas ...
... recent study reports that while teachers and students prefer ... and abortion rates especially in UK schools. When teen ... many influencing factors – the officials said. The study, ... was published in the British Medical Journal, covered about ...
... Fr Angelo D'Agostino SJ, a Jesuit priest, well-known for his ... Monday at the age of 80. ,He was the ... centre for abandoned HIV-positive children. ,Fr Joachim Omolo Ouko ... tribute to Fr Angelo D'Agostino SJ ,He said, "Father D'Agostino ...
... Ovarian cancer continues to be a stealthy killer in Australia ... in the advanced stages. Reports reveal that less than half ... beyond five years. Only about 42% of patients survive when ... a Federal government report. The survival rate is low for ...
... in how insects develop from larvae to adults have ... failure// to be effective in preventing and reducing cardiac ... Davis research published in the early online edition of ... ,The research, led by cardiologist and cell biologist Nipavan ...
... woman and a mother of two children died of breast cancer ... in Sheffield. //Dr.John Philip was not qualified to read mammograms according ... Trust, David Jackson. ,The woman who is identified as ... Philip told her that she was normal. When she went for ...
Cached Medicine News:Health News:Insect Protein Effective for Treating Heart Enlargement, Arrythmias 2
... TraceMasterVue is a cutting-edge ... rich, thin-client functionality and convenient, ... clinical, administrative and information technology ... productivity, lower costs, and improved ...
... testing within reach of virtually any facility...from ... most advanced cardiology hospital. This PC-based system ... options for a Philips ergonomic stress cart ... StressVue is designed to interface with the ...
A component of the 3M Littmann Electronic Stethoscope Model 4000...
... with the challenge of,controlling costs while ... patient data,management is critical. INFINITY modular,patient ... important clinical information,wherever you are in ... concept,makes your job easier. You can ...
Medicine Products: