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Pharma Readiness for Personalized Medicine
Date:10/4/2011

d how does it operate?

* Personalized medicine strategies have typically only been implemented in scenarios where identification of a specific biomarker association is proved out during Phase II/III clinical studies to justify development of a companion diagnostic along with a therapy in anticipation of launch. This practice may miss other scenarios that could ultimately lead to a successful personalized strategy. What are these other scenarios and which drugs in the pipelines of the top ten pharmaceutical companies might benefit from a personalized (i.e. test based) strategy?

* Although the number of PM drug launches is increasing, the pharmaceutical industry is still holding tight to the blockbuster model. What is the shift in the number of PM versus non-PM launches?

* Commercialized PM drugs have performed with varying success on the market. What is the market performance of PM drugs currently in the market?

* In the past few years there have been a number of interesting deals made between the companies. What is the overall activity of the leading pharmaceutical companies of PM-related deals and partnerships?

* The PM environment is a highly competitive landscape. How do the leading pharmaceutical companies rank against each other in terms of their competition?

* The current pharmaceutical and diagnostic targeted therapy models have varying levels of organizational integration and operational alignment. What change is needed in these models to optimize this integration and alignment and where are the pharmaceutical companies in this regard? What is the future outlook for pharmaceutical/diagnostic targeted therapy models?

* There is a complex web of intellectual property (IP) issues surrounding PM in terms of tests, instruments and drugs. What is the role of IP in locking and unlocking PM markets?

Companies Covered

Roche, Merck, Novartis, Amgen, Bristol-Myers Squibb, Sanofi-Aventis, GlaxoSmithKline, As
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