Navigation Links
PharmAthene's Recombinant Butyrylcholinesterase (rBChE) May Play A Neuroprotective Role in Alzheimer's Disease
Date:4/9/2008

ANNAPOLIS, Md., April 9, 2008 /PRNewswire-FirstCall/ -- PharmAthene, Inc. (Amex: PIP) a biodefense company specializing in the development and commercialization of medical countermeasures against chemical and biological threats, announced today that scientists from the Hebrew University of Jerusalem, one of PharmAthene's collaboration partners, have recently obtained new data suggesting that recombinant butyrylcholinesterase (rBChE), a non-pegylated form of Protexia(R), may have neuroprotective benefits.

Recent research conducted by Dr. Hermona Soreq and co-workers at the Alexander Silberman Life Sciences Institute at The Hebrew University of Jerusalem, in collaboration with PharmAthene, examined the role of rBChE in the prevention of amyloid plaques, which are believed to play a role in the development of Alzheimer's disease.

"The role of amyloid plaques in the pathophysiology of Alzheimer's disease is well documented, and a number of approaches have been studied which attempt to block their formation by interfering at critical stages in this complex pathway," said Hermona Soreq, Ph.D., Professor of Molecular Biology and Dean of Sciences at The Hebrew University. "Our preliminary results are especially intriguing as they continue to suggest that rBChE is effective not only in inhibiting plaque formation, but also in potentially attenuating neurotoxicity. The accumulating data provide compelling evidence that rBChE may serve as a natural protector against amyloid toxicity. In view of the empirical evidence gathered to date, the role of rBChE in the pathogenesis of Alzheimer's disease merits closer scrutiny and understanding."

Recent in vitro data have demonstrated that rBChE effectively blocked the formation of amyloid
'/>"/>

SOURCE PharmAthene, Inc.
Copyright©2008 PR Newswire.
All rights reserved

Page: 1 2 3 4 5

Related medicine technology :

1. AlphaMed Pharmaceuticals Announces Breakthrough in the Development of Recombinant Alpha 1-Antitrypsin
2. Baxter Announces Recombinant Factor IX Development Program For Hemophilia B
3. CSL Behring Study in Animal Models Shows Feasibility of Developing a Half-Life Extended Recombinant FVIIa that Retains Biologic Activity
4. Inspiration Biopharmaceuticals Announces Filing of IND for Novel Recombinant Factor IX Product, IB1001, for the Treatment of Hemophilia B
5. CEL-SCI Presents Data for CEL-1000 as a Vaccine Adjuvant with Recombinant Hepatitis B Virus Protein
6. Targeted Genetics Reports on Recombinant DNA Advisory Committee (RAC) Review of its Phase 1/2 Trial of tgAAC94 for Rheumatoid Arthritis
7. Tart Cherries May Reduce Inflammation, Lower Risk for Type 2 Diabetes & Heart Disease
8. Shire Strives to Increase Adherence Among Chronic Kidney Disease Stage 5 Patients
9. Dutch Top Institute Allocates 150 Million Euro to R&D Projects Targeting Early Diagnosis and Treatment of Disease
10. Lilly Launches Its First Phase III Trial for Treatment of Alzheimers Disease
11. Early Research Suggests Umbilical Cord Blood Cell Therapy May Reduce Progression of Alzheimers Disease
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:11/21/2014)... SAN CLEMENTE, Calif. , Nov. 21, 2014 /PRNewswire/ ... Lab Coats and Performance Scrubs carried out a new ... the medical industry,s very first "limited edition" lab ... the first female professors of surgery in the world. ... departure from its unisex predecessors, with a sleek envelope ...
(Date:11/21/2014)... -- PTC Therapeutics, Inc. (NASDAQ: PTCT ) is proud ... Vision, Innovation, and Leadership has been awarded to Stuart ... an individual who has had a significant impact on the ... several decades. "I am honored to receive the ... Ph.D., CEO of PTC Therapeutics, Inc. "When I founded PTC ...
(Date:11/21/2014)... research firm Kalorama information says that 2014 will be ... medical device industry.  The firm thinks the $360 billion-dollar ... growth this year, which led firms to look to ... entrance by acquisition into new competitive zones.  The company ... Global Market for Medical Devices, 5 th Edition ...
Breaking Medicine Technology:Medelita Introduces Medical Industry's First Limited Edition Women's Designer Lab Coat 2PTC Therapeutics Announces CEO, Dr. Stuart Peltz Recipient of The New Jersey Technology Council's 2014 Legend of Technology Award 2PTC Therapeutics Announces CEO, Dr. Stuart Peltz Recipient of The New Jersey Technology Council's 2014 Legend of Technology Award 3Kalorama: 2014 The "Year of The Buy" in Medical Device Industry 2
... Stereotaxis, Inc. (NASDAQ: STXS ) today reported financial ... Third Quarter 2011 Financial Results Revenue ... the year ago period.  The decrease was primarily due to ... for a more efficient solution for complex ablation procedures and ...
... Nov. 7, 2011 Alexza Pharmaceuticals, Inc. (Nasdaq: ... fiscal quarter ended September 30, 2011 and provided a ... September 30, 2011 and 2010, as reported in accordance ... (GAAP), were $13.4 million and $0.6 million, respectively.  The ...
Cached Medicine Technology:Stereotaxis Reports Third Quarter Financial Results 2Stereotaxis Reports Third Quarter Financial Results 3Stereotaxis Reports Third Quarter Financial Results 4Stereotaxis Reports Third Quarter Financial Results 5Stereotaxis Reports Third Quarter Financial Results 6Stereotaxis Reports Third Quarter Financial Results 7Stereotaxis Reports Third Quarter Financial Results 8Alexza Reports 2011 Third Quarter Financial Results and Provides Business Update 2Alexza Reports 2011 Third Quarter Financial Results and Provides Business Update 3Alexza Reports 2011 Third Quarter Financial Results and Provides Business Update 4Alexza Reports 2011 Third Quarter Financial Results and Provides Business Update 5Alexza Reports 2011 Third Quarter Financial Results and Provides Business Update 6Alexza Reports 2011 Third Quarter Financial Results and Provides Business Update 7
(Date:11/21/2014)... Los Angeles, CA (PRWEB) November 21, 2014 ... is now creating picture-perfect smiles for patients in preparation ... are bonded to the fronts of teeth, look completely ... flaws. In certain situations, veneers are also valued for ... for most patients and can be used on one ...
(Date:11/21/2014)... 21, 2014 (HealthDay News) -- Scientists say they,ve mapped the ... from a British man,s brain, in hopes it might help ... 21 in the journal Genome Biology , the tapeworm ... of Chinese ethnicity. "This infection is so rare worldwide ... not diagnosed ... until the worm was pulled out from ...
(Date:11/21/2014)... 21, 2014 The Ohio Children’s Trust ... Ohio Chapter, American Academy of Pediatrics (Ohio AAP, ... education to parents and caregivers throughout Ohio. The new ... 30, 2015, provides $75,000 to continue the campaign that ... Trust Fund is excited to continue partnering with the ...
(Date:11/21/2014)... Midway through the research period for the ... Directory of Health Plans, preliminary data shows volatility in ... Plans is a comprehensive resource with enrollment data and ... The 2015 edition will be available in ... Databases Division, the company’s exclusive in-house research team, have ...
(Date:11/21/2014)... November 21, 2014 CDT PLUS! ... dental practice. It includes everything needed to process dental ... Coding with CDT , CDT 2015 codes are mandatory ... 1, 2014 - December 31, 2014. Dental professionals must ... services on dental claims. There are significant changes in ...
Breaking Medicine News(10 mins):Health News:Los Angeles Porcelain Veneers Dentist, Dr. Kevin Sands, Now Creates Picture-Perfect Smiles for Patients for the Holiday Season 2Health News:Ick! Tapeworm Infecting Man's Brain Yields Genetic Secrets 2Health News:Ohio AAP and Ohio Children’s Trust Fund Continue Partnership for Safe Sleep Education Campaign 2Health News:Ohio AAP and Ohio Children’s Trust Fund Continue Partnership for Safe Sleep Education Campaign 3Health News:Data from Atlantic Information Services’s Forthcoming Directory Shows Volatility in U.S. Health Care Market 2Health News:PMIC Announces CDT PLUS! 2015, the Ultimate Coding Reference for Dentists and Oral Surgeons 2
... Dr Mukesh Haikerwal, today welcomed the Northern Territory ... babies, and encouraged other jurisdictions to follow suit ... disease. ,The NT’s decision came after the ... that it would not be cost-effective to provide ...
... in the science of vaccination has yielded a much-improved ... eradicating and help in fighting// many infectious diseases. ... been slow and painstaking have been so beneficial in ... It was unfortunate however that the health experts in ...
... drink companies have reached an agreement with courts in ... benzene. In Zone Brands Inc, and TalkingRain Beverage// Co ... in their drinks, which increased benzene formation. ... in soft drinks or fruit juices can cause formation ...
... effort to motivate beekeepers to produce sugar-free herbal honey, the ... Pradesh.// ,The National Horticulture Board (NHB) has sent ... to be distributed in 10 of 12 districts in the ... be fed on the stevia herbal plant leaves that are ...
... Jacques Ramsay has recommended that Canadians suffering from severe ... the Twinject, which// provides a double dose in the ... He has also called for manufacturers to ... patients. ,The recommendations follow the investigation into ...
... Employers' Federation (JEF) has confirmed that 22 organizations have ... stigma and discrimination// associated with AIDS in the working ... and labor companies, the employers group has been conducting ... to combat HIV/AIDS discrimination. Creation of the national ...
Cached Medicine News:Health News:Remarkable Progress In Development Of Vaccines 2Health News:Remarkable Progress In Development Of Vaccines 3Health News:Remarkable Progress In Development Of Vaccines 4
... network of door controllers, RoamAlert Integrity Plus ... the coverage area. These receivers pick up ... similar in size and shape, this tag ... RoamAlert ECO and RoamAlert Integrity in one ...
... Radio Frequency Identification (RFID) helps incorporate people ... into the healthcare value chain. The power ... us further automate and optimize business activities ... to tracking pharmaceutical inventories, RFID offers tremendous ...
VACUETTE PaediatricMulti-Sample Needle...
37°C incubator for DianaGel cards....
Medicine Products: