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PharmAthene and Theraclone Sciences Announce Merger Agreement to Create Diversified Biologics Company Targeting Government and Commercial Markets
Date:8/1/2013

l head the new company, commented, "By combining PharmAthene's strong vaccine and biologics development capabilities and government contracting experience, with our clinical antibody candidates and novel discovery platform we are establishing a premier biologics organization with multiple product candidates possessing significant near- and longer-term revenue potential in high-value commercial markets."

Clinical Stage Product Pipeline

The combined company's clinical stage product candidates following the merger will include:

  • TCN-202 CMV Antibody – a broadly-neutralizing mAb that is being developed for the prevention and treatment of human cytomegalovirus (CMV) infections, common in immunocompromised populations, including patients with HIV, cancer and those undergoing organ transplant surgery. TCN-202 has completed a Phase 1 clinical trial, with a Phase 2 study in solid organ transplant scheduled to begin later this year.  The combined company will explore other indications for this program.
  • TCN-032 Influenza Antibody – a broadly-protective mAb being developed for the treatment of pandemic and severe seasonal influenza.  TCN-032 has completed a Phase 2a clinical trial, with results expected to be announced later this year.
  • SparVax® Anthrax Vaccine – a recombinant protective antigen (rPA), next-generation anthrax vaccine being developed for pre and post-exposure prophylaxis of anthrax infection.  One Phase 1 and two Phase 2 clinical trials involving 770 subjects have been completed.  Additional Phase 2 clinical trial testing is planned to begin this year.
  • Valortim® Anthrax Anti-Toxin – a fully human mAb intended for the prevention and treatment
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SOURCE PharmAthene, Inc.
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