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PharmAthene Develops Thermostable Lyophilized rPA Anthrax Vaccine Under a Challenge Grant From the National Institutes of Health
Date:7/8/2010

ANNAPOLIS, Md., July 8 /PRNewswire-FirstCall/ -- PharmAthene, Inc. (NYSE: Amex: PIP), a biodefense company developing medical countermeasures against biological and chemical threats, announced today that it continues to make solid progress in its lyophilized recombinant Protective Antigen (rPA) anthrax vaccine development program.  The Company has recently demonstrated that its lyophilized rPA vaccine candidate is structurally stable and potent at various temperatures up to and including 70 degrees centigrade.  In addition, new non-clinical data, which will be presented next week at the upcoming 2010 International Conference on Emerging Infectious Diseases, July 11-14 in Atlanta, Georgia, demonstrate improved immunogenicity of the lyophilized vaccine formulation when compared to the liquid formulation.

Eric I. Richman, President and Interim Chief Executive Officer, commented, "PharmAthene is committed to working with and serving the needs of our customer, the United States government, through the innovation and development of next generation anthrax vaccines that offer important enhancements over first generation products.  We have developed a portfolio of leading anthrax countermeasures encompassing second and third generation anthrax vaccine candidates based on rPA and a novel anti-toxin therapeutic, which meet these criteria.  We continue to work closely with our partners at the National Institutes of Health (NIH) and the Biomedical Advanced Research and Development Authority to advance these important medical countermeasures to protect Americans at home and on the battlefield."


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