Navigation Links
Pfizer to Acquire FoldRx Pharmaceuticals
Date:9/1/2010

l advisor, while Mintz, Levin, Cohn, Ferris, Glovsky and Popeo P.C., served as its legal advisor.

About Transthyretin Amyloidosis (ATTR-PN)

Transthyretin (TTR) is an amyloidogenic protein secreted by the liver.  Mutations in the TTR gene have been linked to several amyloid conditions.  Deposition of TTR amyloid in the peripheral nerve tissue results in transthyretin amyloid polyneuropathy (ATTR-PN), a sensory, motor and autonomic polyneuropathy.  The disease usually begins in the third or fourth decade with symptoms of peripheral and/or autonomic neuropathy that inexorably progress to involve muscle strength with loss of ambulation.  The patient commonly experiences a profoundly diminished quality of life with a markedly reduced life expectancy (approximately 10 years from first symptom).  Liver transplantation is the only accepted treatment, but it is not uniformly effective, and is associated with significant mortality.  It is estimated that ATTR-PN affects at least 8,000 patients worldwide, the majority of whom are in the European Union.

About tafamidis

Tafamidis is a new chemical entity, first-in-class, oral, disease-modifying agent that stabilizes the protein transthyretin (TTR) and prevents dissociation of the tetramer, the rate-limiting step in TTR amyloidosis.  Tafamidis has orphan drug designation for ATTR-PN in both the U.S. and European Union (EU) and Fast Track designation in the U.S.  FoldRx completed a 128 patient, international, multicenter Phase II/III clinical study of tafamidis for the treatment of ATTR-PN along with additional Phase 2 and 3 trials.

Pfizer Inc: Working together for a healthier world™

At Pfizer, we apply science and our global resources to improve health and well-being at every stage of life.  We strive to set the standard for quality, safety and value in the discovery, development and manufacturing of medicines for p
'/>"/>

SOURCE Pfizer Inc.
Copyright©2010 PR Newswire.
All rights reserved

Page: 1 2 3 4 5 6

Related medicine technology :

1. Wyeths Torisel and Roche/Genentechs Avastin Will Challenge Pfizers Sutent to Become the Clinical Gold Standard for Treatment of Metastatic Renal Cell Carcinoma
2. Kosans Motilin Receptor Agonist, Licensed to Pfizer, Enters Phase 1 Clinical Trial in Gastroesophageal Reflux Disease
3. Coley Pharmaceutical Group and Pfizer Nominate Additional Anti-Cancer Compound for Clinical Development
4. Rigel Announces Initiation of Phase 1 Clinical Trial of R343 for Allergic Asthma by its Partner Pfizer
5. NicOx Announces Pfizer Initiates Phase 2 Clinical Development for PF-03187207 in Japan
6. Tacere Therapeutics Enters Collaboration and License Agreement With Pfizer To Develop and Commercialize RNAi Hepatitis C Drug
7. MannKind Addresses Pfizers Announcement Regarding Exubera
8. Quark Pharmaceuticals Announces First Patient Dosing by Pfizer in Phase II Trial of RNAi Therapy in Diabetic Macular Edema
9. Silence Therapeutics to Receive $1.9m Milestone Payment as Pfizer and Quark Commence Phase II Trial
10. Medarex Receives Milestone Payment from Pfizer for Investigational New Drug Application Filing
11. Pfizer Contributes Critical Data to URMC Drug Safety Initiative
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/19/2014)... -- ChemImage founder and CTO, Patrick J. Treado ... innovative diagnostic procedure for the detection of colorectal cancer ... (SPEC) conference in Krakow, Poland . ... in vitro Diagnostics for Detection of Colorectal Cancer Using ... poster session on Tuesday, August 19, 2014 from 6:30 ...
(Date:8/19/2014)... 19, 2014 Research and Markets has ... of Material, by Technology, by Application & by Region- Global ... The demand for membranes is estimated to ... market to $29.31 billion Membrane technology was first ... as water filtration and kidney dialysis. In modern times, membranes ...
(Date:8/19/2014)... MAHWAH, N.J. , Aug. 19, 2014  Stryker Corporation,s ... TOUR and Champions Tour, is bringing its message of joint ... New Jersey this week at The Barclays.  ... will be in the Spectator Village near the 17 th ... Paramus starting on Thursday, August 21 st . ...
Breaking Medicine Technology:ChemImage Scientists Present Latest Developments for in vitro Detection of Colorectal Cancer Using Raman Molecular Imaging (RMI) at International Conference Focused on Biomedical Applications of Raman Spectroscopy 2Global Membranes (MF, RO, UF, Gas Separation, Dialysis, NF) Market - Forecasts to 2019 2Stryker, The Official Joint Replacement Products Of The PGA TOUR, Welcomes Golf Fans To Its Home State Of New Jersey For The Barclays 2Stryker, The Official Joint Replacement Products Of The PGA TOUR, Welcomes Golf Fans To Its Home State Of New Jersey For The Barclays 3Stryker, The Official Joint Replacement Products Of The PGA TOUR, Welcomes Golf Fans To Its Home State Of New Jersey For The Barclays 4Stryker, The Official Joint Replacement Products Of The PGA TOUR, Welcomes Golf Fans To Its Home State Of New Jersey For The Barclays 5
... Oct. 19, 2009 Amylin Pharmaceuticals, Inc. (Nasdaq: ... obesity program will be presented at Obesity 2009, the ... be held in Washington, D.C. October 24-28. Phase 2 ... be the subject of a late-breaking oral presentation. Obesity ...
... , SILVER SPRING, Md., Oct. 19 The U.S. Food ... to be approved for kidney cancer since 2005. , (Logo: ... oral medication that interferes with angiogenesis, the growth of new ... , Votrient is intended for people with advanced renal ...
Cached Medicine Technology:Amylin Pharmaceuticals Highlights New Data Supporting Therapeutic Potential of Obesity Pipeline at Obesity 2009 2Amylin Pharmaceuticals Highlights New Data Supporting Therapeutic Potential of Obesity Pipeline at Obesity 2009 3Amylin Pharmaceuticals Highlights New Data Supporting Therapeutic Potential of Obesity Pipeline at Obesity 2009 4Amylin Pharmaceuticals Highlights New Data Supporting Therapeutic Potential of Obesity Pipeline at Obesity 2009 5FDA Approves New Treatment for Advanced Form of Kidney Cancer 2
(Date:8/20/2014)... According to a new market research report ... Crystal, Microblinds, Thermographic and Photochromics), by application (Architectural, ... geography - Global Forecast to 2014 - 2020", ... market was worth $1581.4 Million in 2013, and ... at an estimated CAGR of 20% from 2014 ...
(Date:8/20/2014)... (PRWEB) August 20, 2014 The ... leading nonprofit authority on the use of health ... announced the full agenda for its annual fall ... IT Efficiency. WEDI-Con 2014 will take place at ... 20-23, 2014, attracting a diverse cross-section of payers, ...
(Date:8/20/2014)... Fresh from the cradle of a world-class running ... starting blocks. , Urbini, a new collection of versatile baby ... Avi jogger to its lineup. , The Avi has ... inspired by the latest racing styles and a set of ... jogger offers a swift, smooth ride on runs, power-walks and ...
(Date:8/20/2014)... Los Angeles, CA (PRWEB) August 20, 2014 ... clinic has found a cure for it. With extensive research ... Therapy provider named ‘MetroMD’ claims to have perfected the art ... give you a brand new younger look with their revolutionary ... the secrets of the 21st century fountain of youth, the ...
(Date:8/20/2014)... Doctors at the University of Hong Kong claim to ... mice by injecting them with a vaccine that changes their ... on its website. Click here to read the full ... Institute of Microbiology created a vaccine using a protein called ... the vaccine is designed to prevent mesothelioma cells from disabling ...
Breaking Medicine News(10 mins):Health News:Smart Glass Market by Technology Worth $5814 Million by 2020 – New Report by MarketsandMarkets 2Health News:Smart Glass Market by Technology Worth $5814 Million by 2020 – New Report by MarketsandMarkets 3Health News:Smart Glass Market by Technology Worth $5814 Million by 2020 – New Report by MarketsandMarkets 4Health News:Smart Glass Market by Technology Worth $5814 Million by 2020 – New Report by MarketsandMarkets 5Health News:WEDI Releases Full Conference Agenda for Its Annual Fall Conference – WEDI-Con 2014 2Health News:WEDI Releases Full Conference Agenda for Its Annual Fall Conference – WEDI-Con 2014 3Health News:Urbini Breezes Through Summer with New Jogging Stroller 2Health News:MetroMD Offers Revolutionary Anti-aging Hormone Therapy in Hollywood Area 2Health News:New Research Study Finds Vaccine Stops Mesothelioma in Lab Mice, According to Surviving Mesothelioma Website 2
... Steven Reinberg HealthDay Reporter , WEDNESDAY, Aug. 3 ... detect prostate cancer and better evaluate a patient,s treatment options, ... their physician can use to help them decide whether it,s ... said lead researcher Dr. Scott Tomlins, a pathology resident at ...
... , WEDNESDAY, Aug. 3 (HealthDay News) -- Many Americans believe ... is, a new survey finds. The telephone poll of ... be like a video camera that records detailed information for ... the participants believed that once experiences are stored as memory, ...
... , Arriving at a rapid and accurate diagnosis is critical ... officials have had to choose between a highly accurate yet ... new detection method developed at the University of Georgia and ... however, offers the best of both worlds. By coating ...
... Mayo Clinic orthopedic surgeon suspects that the nagging pain ... may be different from what men encounter, and she ... to explore the question. The Society for Women,s Health ... Network on Musculoskeletal Health has awarded a group of ...
... News) -- Vampire bats have heat-detecting molecules that help guide ... long been known that vampire bats know where to bite ... a vein, but the researchers believe this is the first ... Venezuelan researchers investigated wild vampire bats in South America and ...
... ranging from artificial hip joints to dentures and catheters, become ... called biofilms that are resistant to the human immune system ... However, researchers may have a new way of looking ... Iowa biologist David Soll and his colleagues published in the ...
Cached Medicine News:Health News:Urine Test Might Help Predict Prostate Cancer Risk 2Health News:Urine Test Might Help Predict Prostate Cancer Risk 3Health News:Memories Can Be Unreliable, Manipulated 2Health News:UGA researchers use gold nanoparticles to diagnose flu in minutes 2Health News:UGA researchers use gold nanoparticles to diagnose flu in minutes 3Health News:Mayo Clinic examines why knee osteoarthritis afflicts more women than men 2
... if it is not the Flu? Streptococcus ... bacterial "flu-like" infections. The easy-to-use, rapid, urine-based ... within the new 4 hour guidelines. Rapid ... improved patient outcomes and lower overall health ...
Single Use Loading Units with Titanium Staplers for use with MULTIFIRE ENDO TA™ 30 12 mm (Single Use Staplers with Titanium Staplers)....
Single Use Loading Units (SULU's) Knifeless for use with MULTIFIRE ENDO GIA™ 30 12 mm (Single Use Staplers with Titanium Staples)....
Single Use Loading Units (SULU's) with Titanium Staples for use with MULTIFIRE ENDO GIA™ 30 12 mm (Single Use Staplers with Titanium Staples)....
Medicine Products: