Navigation Links
Pfizer Plans Regulatory Submissions of Bosutinib in Chronic Myeloid Leukemia
Date:12/3/2010

bosutinib to market for patients with CML given the need for options in this patient population," said Garry Nicholson, president and general manager of the Pfizer Oncology business unit. "Our ongoing analysis of the bosutinib clinical development program reinforces our belief that bosutinib may provide benefit for patients living with CML, and we are working closely with health authorities and other experts toward our goal of making this promising compound available to patients who need it."

Further details of the BELA study and Study 200 will be presented at the upcoming 52nd Annual Meeting of the American Society of Hematology (ASH) (Abstract #208,(1) December 6 and Abstract #892,(2) December 7, respectively).

About Bosutinib

Bosutinib is an investigational oral dual Src and Abl kinase inhibitor.(1) It is believed that by dual inhibition of the Src and Abl tyrosine kinases, bosutinib may inhibit signaling in CML cells that allows the cells to grow, survive and reproduce.(6)

About Chronic Myeloid Leukemia

Chronic myeloid leukemia (CML), one of the four main types of leukemia,(7) accounts for 15 percent of all leukemias worldwide.(8) A hallmark of CML is an abnormal chromosome known as the Philadelphia Chromosome, a DNA mutation that initiates a series of events leading to the development of Bcr-Abl, a tyrosine kinase that causes CML cells to grow and reproduce rapidly.(9)

Pfizer's Commitment to Hematology

Pfizer Oncology is committed to developing therapies to treat a variety of hematologic malignancies in both adult and pediatric patient populations.  Collectively, hematologic cancers represent the fifth most commonly occurring cancers and the second leading cause of cancer death. While there have been significant advancements in the treatment of hematologic cancers, there continues to be a need for new therapeutic approaches, both for newly diagnosed patients and relapsed patients. I
'/>"/>

SOURCE Pfizer Inc.
Copyright©2010 PR Newswire.
All rights reserved

Page: 1 2 3 4 5

Related medicine technology :

1. Pfizer Announces Positive Phase 3 Trial Results for Axitinib in Patients With Previously-Treated Metastatic Renal Cell Carcinoma (mRCC)
2. Pfizer Launches New Advil® Congestion Relief and Offers 100 Holiday Shoppers Literal Decongestion From Black Friday Crowds
3. Pfizer Launches Global Centers for Therapeutic Innovation, a Network of Research Partnerships, With University of California, San Francisco
4. Amgen, Pfizer, and World-Class Professional Golfer Phil Mickelson Announce Partnership
5. Pfizer Invites Public to View and Listen to Webcast of Pfizer Presentation at Healthcare Conference
6. Pfizer Declares an 18-Cent Fourth-Quarter 2010 Dividend
7. Pfizers Lyrica® (Pregabalin) Capsules CV Receives Approval for Treatment of Peripheral Neuropathic Pain In Japan
8. Pfizer Commences Tender Offer for All Outstanding Shares of King Pharmaceuticals, Inc.
9. Pfizer Enters Into Agreement to Acquire 40 Percent Stake in Teuto in Brazil
10. Biocon and Pfizer Enter Into Global Commercialization Agreement
11. Pfizer Oncology To Present New Clinical Data Across Ten Tumor Types and Multiple Molecular Targets
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/19/2014)...  In the Friday, December 19 edition of ... Information Technology (HIT) features Konica Minolta, the company announced today. The ... several leading healthcare organizations. In addition to the ... such as New York , Chicago ... , Minneapolis and San Francisco ...
(Date:12/19/2014)... TODAY, AEGATE, the leader in medicine verification ... of Peter Fox as Chief Technology Officer ... Officer. Peter has served as Development Director ... Oracle in 2011. Prior to Datanomic, Peter ... and subsequently Convergys, a world renowned billing system for ...
(Date:12/19/2014)... , Dec. 19, 2014  Newport Corporation (NASDAQ: ... Kadia, Ph.D. has joined the company,s Board of ... Officer and a director of Evans Analytical Group, ... evaluation and analytical services to companies in a ... to joining Evans Analytical Group, Dr. Kadia spent ...
Breaking Medicine Technology:USA Today Supplement Featuring Konica Minolta Focuses on Impact of Healthcare IT 2Aegate Appoints new CTO and Chief Channels & Partner Officer 2Aegate Appoints new CTO and Chief Channels & Partner Officer 3Aegate Appoints new CTO and Chief Channels & Partner Officer 4Siddhartha Kadia, Ph.D. Joins Board of Directors of Newport Corporation 2
(Date:12/21/2014)... (PRWEB) December 22, 2014 BellasDress.com offers ... more for women. Today, it announces its BellasDress ... products at its online store. , BellasDress is a ... benefits to its fans through a series of promotions. ... for every customer. , “We are proud of ...
(Date:12/21/2014)... Hills, Ca (PRWEB) December 21, 2014 ... Khanna was a guest at the Aspen Helicopters holiday ... kids and a Santa with sleigh, flown by an ... helicopter appeared invisible; only Santa with sleigh was visible.(please ... during day and night. Dr.Khanna has helped many pilots ...
(Date:12/21/2014)... 21, 2014 When families in Coral Gables ... they call? The new answer is Lice Troopers . ... 33134, their newest treatment center will be the new go-to ... and without the use of harmful chemicals or pesticides. ... January 1, 2015. Like the company’s first clinic (located at ...
(Date:12/21/2014)... AngelWeddingDress.com’s new collection of 2015 spring wedding ... 1,000 new designs in this collection, and all of ... AngelWeddingDress.com promises to provide the most fashionable ... while many fashion trends come and go. If ladies ... at AngelWeddingDress.com is ready to assist. , “These ...
(Date:12/21/2014)... (PRWEB) December 21, 2014 Hundreds ... product liability claims involving a class of Type ... to move forward in a federal multidistrict litigation ... of California, Bernstein Liebhard LLP reports. According to ... established a data cut-off date of February 27, ...
Breaking Medicine News(10 mins):Health News:BellasDress.com Announces its BellasDress Christmas Sale 2Health News:All-Natural Florida Lice Removal Company Opens New Lice Treatment Salon In South Florida 2Health News:2015 Spring Wedding Dresses From AngelWeddingDress Just Released 2Health News:Byetta Lawsuit News: New Order Issued in Federal Incretin Mimetics Litigation, Bernstein Liebhard LLP Report 2Health News:Byetta Lawsuit News: New Order Issued in Federal Incretin Mimetics Litigation, Bernstein Liebhard LLP Report 3Health News:Byetta Lawsuit News: New Order Issued in Federal Incretin Mimetics Litigation, Bernstein Liebhard LLP Report 4
... identify patients who need little, if any, immune suppression ... molecule called HLA-G dimer plays a powerful role in ... tissue, Medical College of Georgia researchers say. , ... in mice and are currently studying whether this molecule ...
... is most likely in younger males, study finds , , ... suffering a heart attack, nearly one in five survivors ... almost 2,000 patients. , Researchers found that 389 (19.9 ... one year after hospitalization for heart attack. This included ...
... such an effect from a nutrient, experts say , , MONDAY, ... levels of vitamin D may be at increased risk of dying ... suggests. , Some 50 percent to 60 percent of ... have insufficient levels of vitamin D. The same is true for ...
... Lyon, France - June 23, 2008 - Sanofi ... announced today that the U.S. Food and Drug ... Toxoids and Acellular Pertussis Adsorbed, Inactivated Poliovirus and ... vaccine is indicated for active immunization against diphtheria, ...
... June 23 Marketing budgets are usually,among the ... tell,Sally Gilbert., Gilbert is creator of the ... for health-conscious,consumers taking place in Charlotte in early ... spent $9,000 on marketing already and plans to,spend ...
... MADISON, N.J., June 23 Quest Diagnostics,Incorporated (NYSE: ... diagnostic,testing, information and services, announced that it is ... Tuesday, June 24, 2008. The Quest,Diagnostics presentation is ... The presentation will be webcast live during the ...
Cached Medicine News:Health News:Immune Molecule Key to Preventing Organ Rejection 2Health News:Angina Strikes 1 in 5 Heart Attack Survivors 2Health News:Low Vitamin D Could Raise Death Risk 2Health News:Low Vitamin D Could Raise Death Risk 3Health News:US FDA licenses Sanofi Pasteur's new pediatric combination vaccine, pentacel 2Health News:US FDA licenses Sanofi Pasteur's new pediatric combination vaccine, pentacel 3Health News:Maverick Marketers Defy Economic Slowdown 2
... is designed to give accurate and ... neurosurgical intensive care, trauma, and operating ... and easy to use, and provides ... built-in audible alarm alerts attending staff ...
A portable, easy to use, dual-channel laser-Doppler tissue perfusion and temperature monitoring system, at a remarkably affordable price....
... highly featured laser doppler system for ... from multiple tissue sites. This latest ... Signal Processing (DSP) and laser Doppler ... simple to use, multi-channel monitor, setting ...
... highly featured laser doppler system for ... from multiple tissue sites. This latest ... Signal Processing (DSP) and laser Doppler ... simple to use, multi-channel monitor, setting ...
Medicine Products: