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Pfizer Oncology To Present New Clinical Data Across Ten Tumor Types and Multiple Molecular Targets
Date:10/7/2010

NEW YORK, Oct. 7 /PRNewswire-FirstCall/ -- Pfizer Oncology will present new data across its portfolio representing novel approaches to researching treatments for patients with rare and difficult-to-treat cancers.  These results will be presented at the 35th European Society for Medical Oncology (ESMO) Congress in Milan, Italy from October 8-12.  

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"Pfizer (NYSE: PFE) has focused its oncology research on targeting molecular drivers and pathways in various cancers, such as EGFR, ALK and IGF-1R," said Dr. Mace Rothenberg, senior vice president of clinical development and medical affairs for Pfizer's Oncology Business Unit. "We are committed to using this approach to seek treatments for well-known, difficult-to-treat and rare tumor types that have few or no therapeutic options and where we can make a big impact in defined patient populations."

At ESMO, Pfizer will present data on key compounds from its portfolio, which includes:  

  • PF-00299804

Updated results from a global, randomized Phase 2 trial evaluating the anti-tumor activity and safety of PF-00299804 compared to erlotinib in patients with NSCLC following progression on treatment with one or more chemotherapy regimens (Abstract #365PD, October 10).(1)  In addition, preliminary efficacy and safety data from a Phase 2 study evaluating PF-00299804 as first-line treatment in patients with advanced NSCLC whose tumors are likely to carry the EGFR mutation will be presented as a late breaker in a Proffered Paper session (Abstract #LBA18, October 11).(2)  

PF-00299804 is an investigational, oral, pan-HER (pan-human epidermal growth factor receptor) inhibitor.(2)  PF-00299804
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SOURCE Pfizer Inc.
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