Navigation Links
Pfenex Inc. awarded a subcontract by Leidos to develop a scalable cGMP production process for a second key malaria antigen
Date:10/29/2013

SAN DIEGO, Oct. 29, 2013 /PRNewswire/ -- Pfenex Inc. today announced that Leidos Holdings, Inc. (NYSE: LDOS) (formerly SAIC) has awarded Pfenex a subcontract to develop a robust, scalable, cGMP-ready production process for large-scale production of the blood-stage malaria antigen Plasmodium falciparum reticulocyte-binding homolog 5 (Rh5). This contract is a result of successful pre-clinical studies performed by Leidos collaborators to evaluate the Rh5 antigen that was produced using the Pfēnex Expression TechnologyTM platform. The subcontract is funded with federal funds from Leidos' prime Malaria Vaccine Production and Support Services (MVPSS) contract (N01.AI.05421) from the National Institute of Allergy and Infectious Diseases (NIAID).

This is the second subcontract awarded to Pfenex for the development of critical, hard-to-express malaria antigens.  Leidos had previously awarded Pfenex a subcontract to develop a scalable, cGMP-ready production process for large-scale production of full length Circumsporozoite protein (CSP) from P. falciparum.

"We are pleased to be awarded this contract as we expand our effort to find an effective therapy for malaria," stated Bertrand C. Liang, Pfenex's Chief Executive Officer. "Pfēnex Expression TechnologyTM has once again demonstrated its ability to efficiently produce a high–value, complex protein enabling the potential of a multivalent malaria vaccine."

Pfenex will immediately commence process development activities while continuing to provide materials to Leidos and NIAID for ongoing preclinical studies. 

"Working with Pfenex and NIAID on this program is an important step in the development of an effective malaria vaccine," said James Pannucci, Ph.D., vice president of the Leidos Health Life Sciences team.  "We hope our work will lead to new discoveries and have a profound effect on the world's health." The Leidos Life Science team operates a virtual drug development enterprise that bridges the gap between federal agencies and commercial clients, along with a modest portfolio of vaccine and therapeutic candidates.

About Pfenex Inc.  
Pfenex Inc. is a biotechnology company developing biosimilars and innovative vaccines to address unmet and growing global healthcare needs.  Utilizing the company's core technology, Pfēnex Expression Technology™ for recombinant protein expression, Pfenex is able to rapidly develop and produce high quality biopharmaceuticals. In addition, Pfenex also produces and markets research proteins and reagent proteins for the research and drug development community through its Reagent Proteins division.  For more information please visit www.pfenex.com 


'/>"/>
SOURCE Pfenex Inc.
Copyright©2012 PR Newswire.
All rights reserved

Related medicine technology :

1. Pfenex Inc. and Agila Biotech Private Limited Announce Joint Venture to Develop Biosimilar Products for the Global Market
2. Biomedical Advanced Research and Development Authority (BARDA) Exercises Option with Pfenex Inc. To Extend Contract for the Development of a Recombinant Protective Antigen (rPA) Based Anthrax Vaccine
3. AMRI Awarded Development and Manufacture Contract from the UK Government
4. Numotion Awarded Best Complex Rehab Provider
5. Isis Pharmaceuticals Stanley Crooke Awarded Corporate Forums Director of the Year
6. Access Pharmaceuticals Awarded Second European Patent for MuGard
7. Jeannette R. Jakus, MD, MBA, Awarded American Academy of Dermatology Translational Biotechnology Fellowship
8. Oligomerix Awarded Phase IIB Grant From the NIH to Discover Drugs that Inhibit Alzheimers Disease Progression
9. NovelMed Awarded NIH Fast Track SBIR Grant for $1.43 Million to Advance Development of its Anti-Complement Antibody for Orphan Disease
10. Carolina Piedmont Capital Awarded VOSB Certification
11. B. Braun Awarded Premier Healthcare Alliance Contract for Dual-Source IV
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/18/2017)... , Jan. 18, 2017  Tarix Orphan LLC today ... granted a Rare Pediatric Disease (RPD) designation for the ... Dystrophic Epidermolysis Bullosa (RDEB), a rare genetic skin disorder. ... treatment is limited to supportive care. "The ... Drug Designation previously granted by the FDA in this ...
(Date:1/18/2017)...  Robust competition in the private marketplace is ... prices, according to a new study by ... the first to examine the share of prescription medicine ... managers (PBMs), health plans and other stakeholders in the ... first to show what happens when the list price ...
(Date:1/17/2017)... 2017 North America Insulin Delivery Market Outlook ... America Insulin Delivery Market Outlook to 2022", provides key ... The report provides value, in millions of US dollars, ... segments - Insulin Pens, Insulin Pumps, Insulin Syringes and ... company shares and distribution shares data for each of ...
Breaking Medicine Technology:
(Date:1/18/2017)... ... January 18, 2017 , ... The VA Maryland Health Care ... a research project focused on multiple sclerosis (MS). Led by Christopher M. Jewell, ... control the disease without compromising normal immune function that often occurs during autoimmune ...
(Date:1/18/2017)... ... January 18, 2017 , ... A Palm Beach doctor plans to ... an international charity that provides free surgery to poor children suffering from cleft lip ... past I have run to support the efforts of the American Heart Association and ...
(Date:1/18/2017)... ... ... At Hallmark Nameplate, their commitment to quality is what sets them apart. ... This certification is another way they are making constant strides to provide all customers ... , The ISO 13485 Certification is a major accomplishment for Hallmark Nameplate and will ...
(Date:1/18/2017)... ... January 18, 2017 , ... ... support an aid project with the donation of cochlear implants. In February 2017, ... hearing and thus a fair chance of leading an independent life. This engagement ...
(Date:1/17/2017)... ... 17, 2017 , ... January is National Stalking Awareness Month (NSAM), now in its ... corners and commit the crime of stalking, a very real danger to many in our ... factor in stalking and other crimes. , “Stalking: know it. Name it. Stop it.”—so reads ...
Breaking Medicine News(10 mins):