Navigation Links
Pfenex Inc. awarded a subcontract by Leidos to develop a scalable cGMP production process for a second key malaria antigen
Date:10/29/2013

SAN DIEGO, Oct. 29, 2013 /PRNewswire/ -- Pfenex Inc. today announced that Leidos Holdings, Inc. (NYSE: LDOS) (formerly SAIC) has awarded Pfenex a subcontract to develop a robust, scalable, cGMP-ready production process for large-scale production of the blood-stage malaria antigen Plasmodium falciparum reticulocyte-binding homolog 5 (Rh5). This contract is a result of successful pre-clinical studies performed by Leidos collaborators to evaluate the Rh5 antigen that was produced using the Pfēnex Expression TechnologyTM platform. The subcontract is funded with federal funds from Leidos' prime Malaria Vaccine Production and Support Services (MVPSS) contract (N01.AI.05421) from the National Institute of Allergy and Infectious Diseases (NIAID).

This is the second subcontract awarded to Pfenex for the development of critical, hard-to-express malaria antigens.  Leidos had previously awarded Pfenex a subcontract to develop a scalable, cGMP-ready production process for large-scale production of full length Circumsporozoite protein (CSP) from P. falciparum.

"We are pleased to be awarded this contract as we expand our effort to find an effective therapy for malaria," stated Bertrand C. Liang, Pfenex's Chief Executive Officer. "Pfēnex Expression TechnologyTM has once again demonstrated its ability to efficiently produce a high–value, complex protein enabling the potential of a multivalent malaria vaccine."

Pfenex will immediately commence process development activities while continuing to provide materials to Leidos and NIAID for ongoing preclinical studies. 

"Working with Pfenex and NIAID on this program is an important step in the development of an effective malaria vaccine," said James Pannucci, Ph.D., vice president of the Leidos Health Life Sciences team.  "We hope our work will lead to new discoveries and have a profound effect on the world's health." The Leidos Life Science team operates a virtual drug development enterprise that bridges the gap between federal agencies and commercial clients, along with a modest portfolio of vaccine and therapeutic candidates.

About Pfenex Inc.  
Pfenex Inc. is a biotechnology company developing biosimilars and innovative vaccines to address unmet and growing global healthcare needs.  Utilizing the company's core technology, Pfēnex Expression Technology™ for recombinant protein expression, Pfenex is able to rapidly develop and produce high quality biopharmaceuticals. In addition, Pfenex also produces and markets research proteins and reagent proteins for the research and drug development community through its Reagent Proteins division.  For more information please visit www.pfenex.com 


'/>"/>
SOURCE Pfenex Inc.
Copyright©2012 PR Newswire.
All rights reserved

Related medicine technology :

1. Pfenex Inc. and Agila Biotech Private Limited Announce Joint Venture to Develop Biosimilar Products for the Global Market
2. Biomedical Advanced Research and Development Authority (BARDA) Exercises Option with Pfenex Inc. To Extend Contract for the Development of a Recombinant Protective Antigen (rPA) Based Anthrax Vaccine
3. AMRI Awarded Development and Manufacture Contract from the UK Government
4. Numotion Awarded Best Complex Rehab Provider
5. Isis Pharmaceuticals Stanley Crooke Awarded Corporate Forums Director of the Year
6. Access Pharmaceuticals Awarded Second European Patent for MuGard
7. Jeannette R. Jakus, MD, MBA, Awarded American Academy of Dermatology Translational Biotechnology Fellowship
8. Oligomerix Awarded Phase IIB Grant From the NIH to Discover Drugs that Inhibit Alzheimers Disease Progression
9. NovelMed Awarded NIH Fast Track SBIR Grant for $1.43 Million to Advance Development of its Anti-Complement Antibody for Orphan Disease
10. Carolina Piedmont Capital Awarded VOSB Certification
11. B. Braun Awarded Premier Healthcare Alliance Contract for Dual-Source IV
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/5/2017)... The Cincinnati location of ... (NYSE: DPLO), has been awarded a Top Workplaces 2017 ... Results are based on an employee survey administered by WorkplaceDynamics, ... improvement. The survey measures several aspects of workplace culture, including ... ...
(Date:6/1/2017)... BLUE BELL, Pa. , June 1, 2017 /PRNewswire/ ... Nutriceuticals (PRN) and Veterinarian Recommended Solutions (VRS), and KD ... direct investment in Nutriceutical Holdings by KD Pharma Group. ... Nutriceutical Holdings with the option to acquire the entire ... ideal partner in KD. They are committed to growing ...
(Date:5/29/2017)... May 29, 2017  Cellect Biotechnology Ltd. (NASDAQ: ... which enables the functional selection of stem cells, today ... the first quarter ended March 31 st , 2017. ... accomplishments in the first quarter of 2017," said Dr. ... we announced the treatment of the first blood cancer ...
Breaking Medicine Technology:
(Date:6/26/2017)... (PRWEB) , ... June 26, 2017 , ... ... and urinary leakage is revolutionizing the way women look and feel about themselves ... the problem of female sexual dysfunction and urinary leakage head on with a ...
(Date:6/26/2017)... ... 2017 , ... New patients with missing teeth in Fitchburg, WI, ... referral. Dr. Cotey is a trusted dentist who has placed many dental implants and ... with missing teeth in Fitchburg, WI, are encouraged to find out if they are ...
(Date:6/25/2017)... CA (PRWEB) , ... June 25, 2017 , ... An ... green and growing foliage and plants, and along with that; a humdinger of an ... allergy sufferers, it also means an increase in misery-causing grass and weed pollen. ...
(Date:6/24/2017)... ... June 24, 2017 , ... Genes Advice, ... medications in select Florida and Texas doctors' offices and clinics. This breakthrough testing ... of genetic testing recognizes the role genes play in determining an individual's tolerance ...
(Date:6/24/2017)... ... June 24, 2017 , ... Doorknobs are for convenience, ... such as getting a guard dog or having an alarm system installed. But unless ... against forced entry. Yair Frenkel, owner of TX Premier Locksmith in Killeen, TX says: ...
Breaking Medicine News(10 mins):