Navigation Links
Pevion's Therapeutic Candida Vaccine Generates Functional B Cell Memory in all Vaccinees
Date:1/17/2012

BERN, Switzerland, January 17, 2012 /PRNewswire/ --

Pevion Biotech AG today announced further data from the ongoing clinical study of its therapeutic Candida vaccine PEV7, demonstrating the generation of specific and functional B cell memory in 100% of vaccinees. Furthermore, the results again confirm the capability of Pevion's second generation virosomal vaccine platform to induce strong and long-lasting immunity in humans against otherwise weak antigens .

Following the previously announced positive safety and immunogenicity results of PEV7, the Company further investigated the vaccine-induced generation of B cell memory. To this end, half of the group of volunteers vaccinated with the intramuscular low dose of PEV7 received a single booster immunization fourteen months after the primary vaccination course. All vaccinees showed a rapid, specific response either in serum or in cervicovaginal secretion or in both, after antibody titers had come down to baseline six months prior to the boost in this low-dose group.

"Based on analyses of antibody functionality, as monitored by competitive target inhibition, and antigen specific reactivity, we have evidence for an affinity maturation of these antibodies," explained Christian Moser, Head of Research at Pevion. "We are very satisfied to see such an excellent induction of memory by the PEV7 vaccine even at low dose, and we are now looking forward to obtain the results from the high-dose group. Moreover, this is the first time for a second generation virosome-based vaccine that we verified the generation of memory in humans by means of a booster immunization."

The follow-up of the group of volunteers vaccinated with the intramuscular high dose of PEV7 is ongoing and so far has shown high and persistent antibody titers until six months after completion of the vaccination course. In order to evaluate the intravaginal application of PEV7 in capsule form, an additional study arm is ongoing.
'/>"/>

SOURCE Pevion Biotech AG
Copyright©2010 PR Newswire.
All rights reserved

Page: 1 2 3

Related medicine technology :

1. Stemline Therapeutics, Inc. Names Eric K. Rowinsky, M.D. Chief Medical Officer and Head of Research and Development
2. Xenon to Collaborate with Genentech on Discovery of Novel Targeted Pain Therapeutics
3. Silence Therapeutics Signs Collaboration with miRagen Therapeutics to Evaluate Delivery of Novel microRNA-based Therapeutics
4. Lightlake Therapeutics Inc. to Apply Companys Patented Technology in the Development of Premenstrual Syndrome Overeating Treatment
5. Pearl Therapeutics Announces Successful Completion of Phase 2b Safety and Efficacy Studies of COPD Combination, PT003
6. Orexigen Therapeutics to Present at the J.P. Morgan Healthcare Conference
7. Halo Therapeutics HT-100 Receives FDAs Orphan Designation for Duchenne Muscular Dystrophy
8. Echo Therapeutics Announces $3.6 Million Warrant Exercises
9. Echo Therapeutics to Present at Biotech Showcase 2012 in San Francisco
10. Orexigen® Therapeutics Completes Public Offering of Common Stock and Warrants to Purchase Common Stock
11. AuraSense Therapeutics Secures Series B Equity Investment
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/24/2014)... SAN DIEGO , Dec. 24, 2014 /PRNewswire/ ... the West, developing the proprietary Natural Killer (NK) ... announces that Dr. Patrick Soon-Shiong , NantWorks ... into a definitive agreement to purchase approximately $48 ... In connection with the investment, he will be ...
(Date:12/24/2014)... Dec. 23, 2014 PuraMed BioScience®, Inc., (OTC ... (OTC) medicinal and healthcare products, announced it received the ... a hemp-based, advanced headache relief product, for planned distribution ... Colorado , Washington State ... With the MigraPure H Advanced headache relief gel formulation ...
(Date:12/24/2014)... LifeScienceIndustryResearch.com adds 2014 ... Industry of 178 pages providing 10 company ... The 2014 Market Research Report ... professional and deep research report on Global ... report introduces Disposable Syringe basic information including ...
Breaking Medicine Technology:Conkwest Announces $50m In Strategic Investments And Appoints NantWorks Founder, Dr. Patrick Soon-Shiong As Co-Chairman Of The Board 2Conkwest Announces $50m In Strategic Investments And Appoints NantWorks Founder, Dr. Patrick Soon-Shiong As Co-Chairman Of The Board 3Conkwest Announces $50m In Strategic Investments And Appoints NantWorks Founder, Dr. Patrick Soon-Shiong As Co-Chairman Of The Board 4Conkwest Announces $50m In Strategic Investments And Appoints NantWorks Founder, Dr. Patrick Soon-Shiong As Co-Chairman Of The Board 5PuraMed BioScience Nears Final Stages Needed for Distribution of MigraPure H 2PuraMed BioScience Nears Final Stages Needed for Distribution of MigraPure H 3World Disposable Syringe Market 2014 Report: China and Regional Analysis 2World Disposable Syringe Market 2014 Report: China and Regional Analysis 3World Disposable Syringe Market 2014 Report: China and Regional Analysis 4World Disposable Syringe Market 2014 Report: China and Regional Analysis 5
(Date:12/26/2014)... 2014 Parker & Sons, Inc. ... in heating, cooling and plumbing contractor services throughout ... services in 2014 with regard to air-conditioning systems. ... is known for its incredibly hot summers. Working ... intricacies and details of a wide variety of ...
(Date:12/25/2014)... 2014 The click strand ... strength and durability. Today, the business announces a ... valid until Jan. 30, 2015. , Click strand ... hardwood. BambooFlooringChina.com is a well-known brand in the ... to find a reliable bamboo flooring supplier. , ...
(Date:12/25/2014)... 2014 Product liability lawsuits filed in ... ( http://www.consumerinjurylawyers.com/DePuy/ ) continue to move forward in federal ... issued in the U.S. District Court, Northern District of ... open conference on January 7, 2015, at the Paul ... West Palm Beach, Florida. The Conference is scheduled to ...
(Date:12/25/2014)... Recently, Dylan Queen, a famous online company supplying ... of discounted prom dresses, most of which are priced ... the company, the promotion is valid until Jan. 22, ... the UK market. , The prom dresses in this ... styles: A-line strapless, empire strapless chiffon, one shoulder, floor-length, ...
(Date:12/25/2014)... sells many bamboo products and the business is famous ... announces big discounts on its bamboo mats , which ... the world’s leader in bamboo flooring. According to the ... 2015. , The bamboo mats are made from well-treated ... the bamboo strips for the mats are boiled and ...
Breaking Medicine News(10 mins):Health News:Parker & Sons Announces Record Demand For 24 Hour Emergency Services In 2014 With Regard To Air-Conditioning Systems 2Health News:Parker & Sons Announces Record Demand For 24 Hour Emergency Services In 2014 With Regard To Air-Conditioning Systems 3Health News:BambooFlooringChina.com: click strand woven bamboo flooring promotion valid until Jan. 30, 2015. 2Health News:Federal Court Overseeing DePuy ASR Hip Lawsuit Set to Convene Conference in January, Bernstein Liebhard LLP Reports 2Health News:Federal Court Overseeing DePuy ASR Hip Lawsuit Set to Convene Conference in January, Bernstein Liebhard LLP Reports 3Health News:Dylan Queen: Cheap Prom Dresses for the UK Market 2Health News:Various Styles of Bamboo Mats in Many Colors from BambooFlooringChina.com 2
... timely reminder of the issues surrounding the binge drinking ... and alcohol, a team lead by Professor Christine Griffin, ... by the Economic and Social Research Council (ESRC) suggests ... on the role of marketing practices in shaping young ...
... Patrick J. McMahon, CPA, was named the Senior Vice ... System. In his new position, McMahon will be part ... Sisters of Charity Health System (SCHS) as it continues ... overall operations of its 20 health, human service and ...
... to more effective ways to control weight , , FRIDAY, Dec. ... activities at suppressing appetite, according to a U.K. study. ... in three types of sessions. In one, they ran for ... hours. In another, they did 90 minutes of weight lifting ...
... DIET Web Site, Features Weight Loss Calculators, Recipes, Customer Rewards Program, ... ... (PRWEB) December 26, 2008 -- Dr. Siegal,s Direct Nutritionals, LLC, the ... DIET® brand weight loss system and hunger-busting diet cookies and diet ...
... would be a real advance since these cells more ... (HealthDay News) -- Researchers say they,ve found a formula ... a mammal, including long-sought rat stem cells. , ... able to mimic human disease in readily produced, genetically ...
... A dentist who owns a successful dental practice and center for ... weight gain during the holiday may contribute to a energy-robbing and ... the neck region, can further complicate breathing while sleeping. , ... ...
Cached Medicine News:Health News:T'is the season to be jolly? 2Health News:Patrick J. McMahon Named Senior Vice President/CFO of Sisters of Charity Health System 2Health News:Patrick J. McMahon Named Senior Vice President/CFO of Sisters of Charity Health System 3Health News:Vigorous Treadmill Workout Curbs Appetite Hormones 2Health News:Dr. Siegal's COOKIE DIET Launches All-New Web Site and Shortens URL to CookieDiet.com 2Health News:Dr. Siegal's COOKIE DIET Launches All-New Web Site and Shortens URL to CookieDiet.com 3Health News:Dr. Siegal's COOKIE DIET Launches All-New Web Site and Shortens URL to CookieDiet.com 4Health News:Scientists May Isolate Stem Cells From Rats, Other Mammals 2Health News:Holiday Weight Gain May Contribute to Sleep Apnea Extra Pounds May Produce Severe Problems for Adults 2
Thermal Seal, Clear, Bulk...
Acetate Plate Sealers 100/Box...
... seals provide an adhesive-based sealing option for ... adhesive layer ensures secure sample storage or ... sealing during thermal cycling when supplemental pressure ... perforated end-tabs can be removed when using ...
TD silicone foam compression pad. Use with plates sealed with TDX or OptiTape....
Medicine Products: