Navigation Links
Peregrine Pharmaceuticals Submits Clinical Protocol to Initiate Bavituximab Phase II Trial in Patients With Metastatic Breast Cancer
Date:9/10/2007

tly completed Phase Ib cancer study, which showed that the combination of bavituximab with paclitaxel and carboplatin might be especially promising in breast cancer patients. We look forward to assessing bavituximab's potential in this larger trial in women battling metastatic breast cancer."

Tumor response will be evaluated every other month using Response Evaluation Criteria in Solid Tumors (RECIST) parameters. The trial is being conducted according to International Conference on Harmonization (ICH) and Good Clinical Practices (GCP) guidelines.

According to the World Health Organization, metastatic breast cancer is the most commonly diagnosed cancer in women, and is second only to lung cancer as a leading cause of female cancer deaths. The National Cancer Institute estimates that 178,480 U.S. women will be diagnosed with cancer of the breast in 2007 and 40,460 women will die of the disease.

Bavituximab is a monoclonal antibody that binds to a phospholipid called phosphatidylserine that is normally located inside normal cells, but which becomes exposed on the outside of the cells that line the blood vessels of tumors, creating a specific target for anti-cancer treatments. Bavituximab is believed to help mobilize the body's immune system to destroy the blood vessels needed for tumor growth and spread. In a Phase lb trial in advanced cancer patients, bavituximab plus chemotherapy appeared to have a safety profile consistent with chemotherapy alone and showed positive signs of clinical activity, achieving objective response or disease stabilization in 50% of the evaluable patients. A protocol for a Phase ll trial of bavituximab in combination with chemotherapy in patients with non-small cell lung cancer (NSCLC) is currently undergoing regulatory review in India. Bavituximab is also in clinical trials in the U.S. in patients with advanced solid tumors and in patients co-infected with HCV and HIV.

Safe Harbor Statement: Statements in this press r
'/>"/>

SOURCE Peregrine Pharmaceuticals, Inc.
Copyright©2007 PR Newswire.
All rights reserved

Page: 1 2 3 4

Related medicine technology :

1. Peregrine Pharmaceuticals Reports Positive Top-Line Results in Bavituximab Combination Therapy Trial in Advanced Cancer Patients
2. Positive Results Using Affitech-Identified Human Antibody That Blocks VEGF Binding to VEGF Receptor 2 in Preclinical Cancer Model Reported by Peregrine
3. Peregrine Pharmaceuticals Highlights Significant Advances in the Companys Clinical and Preclinical Cancer Programs Presented This Week at the AACR Annual Meeting
4. Data Presented at AACR Meeting Shows Peregrines Immunocytokine Fusion Proteins Reduce Growth of B-Cell Lymphoma Tumors by 85% in Preclinical Studies
5. Data Presented at AACR Meeting Show Peregrines Bavituximab Equivalent Can Generate Curative Immune Responses as Part of a Vaccine-Like Regimen in Preclinical Models of Aggressive Brain Cancer
6. Data Presented at AACR Meeting Shows Peregrines Selective Anti-VEGF Antibodies are as Effective as Avastin(R) in Preclinical Cancer Models
7. Inspiration Biopharmaceuticals Presents Data From Hemophilia Program at International Society On Thrombosis and Haemostasis (ISTH) Annual Meeting
8. BioSante Pharmaceuticals Announces New Findings for Potential Bird Flu Vaccine
9. Portola Pharmaceuticals Announces Positive Data from a Phase II Study of its Factor Xa Inhibitor at the XXI Congress of the International Society on Thrombosis and Haemostasis
10. Manhattan Pharmaceuticals Announces Results of Phase 2a Studies for Oral Oleoyl-estrone
11. Auxilium Pharmaceuticals to Present at the 2007 CEUT Emerging Growth Opportunities Conference
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/29/2014)... -- ChemImage will present a workshop focused on hyperspectral ... Science Society,s 22 nd International Symposium on ... .  Forensic Scientists will be in attendance ... can bring to examination procedures. ... Development at ChemImage, will host a workshop during ...
(Date:8/29/2014)... -- In part four of a blog series ... a strategic asset, Mary Baxter, MBA, RPh ., ... Innovation Delivery Solutions business, discusses how expanding patient access ... patients. "Every hospital pharmacist knows that filling ... in a value-based healthcare world," Baxter says. "For the ...
(Date:8/29/2014)... Calif. , Aug. 29, 2014  Pacific Medical ... its new website design . The main website, ... that showcases the company,s new services and content relevant ... implementing a new streamlined design, viewers can now better ... for health care practices and create a more visible ...
Breaking Medicine Technology:ChemImage to Discuss Hyperspectral Imaging for Forensic Investigation at the ANZFSS 22nd International Symposium on the Forensic Sciences 2ChemImage to Discuss Hyperspectral Imaging for Forensic Investigation at the ANZFSS 22nd International Symposium on the Forensic Sciences 3Five Ways Hospital Pharmacies Can Fulfill Their Quality Care Mission 2Five Ways Hospital Pharmacies Can Fulfill Their Quality Care Mission 3Five Ways Hospital Pharmacies Can Fulfill Their Quality Care Mission 4PMDS Announces New Website 2
... Implementation of electronic medical records (EMR) by healthcare providers ... so many reports, the determining factor responsible for this ... reported by USA Today, upfront costs (which include purchasing ... $36,000 per physician. In addition, the learning curve for ...
... N.J., Oct. 30 Novo Nordisk Inc. announced the ... hemophilia(TM) campaign through a rebranded Web site and ... face many daily challenges, and Novo Nordisk is committed ... a lifetime of possibilities. , These new online resources ...
Cached Medicine Technology:Electronic Medical Record System and More 2Electronic Medical Record System and More 3Novo Nordisk is Changing Possibilities in Hemophilia 2Novo Nordisk is Changing Possibilities in Hemophilia 3
(Date:8/30/2014)... Colorado (PRWEB) August 30, 2014 Daily ... method that keeps anxiety and panic attacks under control ... "Panic Away" program review describes this new method ... sufferers control panic attacks and overcome general anxiety related ... and successful is the fact that it can be ...
(Date:8/30/2014)... Plains, NJ (PRWEB) August 30, 2014 ... first facilities in New Jersey and even in the ... technology that takes inches off of patients’ waists with ... freezing cells in small sections, Vanquish is more inclusive ... pain. Patients lay comfortably under panels about one ...
(Date:8/30/2014)... RB SEO Services, a well-recognized internet ... small businesses. , RBSEO Services knows this very well ... engine optimization service. So, the company has introduced this ... , On being asked about the service, a ... cost SEO service because many small businesses expressed their ...
(Date:8/30/2014)... The establishment and creation of Ideal ... of the main strategies of the Church of ... around the world. , Architecturally stellar buildings with ... and trainers deliver L. Ron Hubbard's spiritual technology ... demonstrate that significant reduction in crime, major decrease ...
(Date:8/30/2014)... August 30, 2014 Acne is a common problem ... acne is nothing more than a daily nuisance, for some, it ... cases of acne can even lead to dramatic mood swings and ... try anything to clear up their skin. In some cases, that ... money through trial and error, those on a quest for clearer ...
Breaking Medicine News(10 mins):Health News:Panic Away Review Reveals New Natural Remedy for Anxiety Patients 2Health News:NJ Top Docs Presents, The Plastic Surgery Group 2Health News:RBSEO Services Introduces Low Cost SEO Service for Small Businesses 2Health News:Cradle of Aviation Museum Opens Its Doors to Long Island Scientologists 2Health News:Acne Treatment Reviews Added to Popular Treatment Website 2
... Makes Programs More Affordable, WASHINGTON, April 7, ... policies managed by the Department,of Veterans Affairs (VA) ... to,improved investment earnings and a reduction in non-combat ... covered by Servicemembers,Group Life Insurance (SGLI) and veterans ...
... to protect the spinal cord from toxins may play a ... as ALS or Lou Gehrigs disease, according to research published ... mark the first time that scientists have witnessed molecular changes ... finding opens up a new front in studies of ALS, ...
... Renowned doctor and former Attending Physician to Congress is the latest ... addition to the expert team at ... doctor evaluation service listing more than 700,000 active U.S.,doctors, today announced ... independent advisor. Dr. Krasner will lend his expertise to,identify innovative ways ...
... for Intelligence Analysis Program, SAN DIEGO and ... Corporation (NYSE: SAI ) today announced,it was ... Defense Intelligence,Agency (DIA). This multiple-award, indefinite-delivery/indefinite-quantity,contract will support ... dollar value for all task orders that can ...
... interfere with family time, grades and nutrition, study finds , ... may poignantly plead that he or she is the ... health experts recommend that parents stand their ground and keep ... be a good reason for this. The latest research, published ...
... and Features Similar to, Market-Leading Systems in an Easy-to-Use, Accessible and Affordable Format ... ... at the Accuri Booth at ... April 7, 2008 Accuri Cytometers, Inc.,today announced the commercial launch of the Accuri C6 ...
Cached Medicine News:Health News:VA Announces SGLI and VGLI Premium Reductions 2Health News:Leaky blood vessels open up nerve cells to toxic assault in Lou Gehrig's disease 2Health News:Leaky blood vessels open up nerve cells to toxic assault in Lou Gehrig's disease 3Health News:Leaky blood vessels open up nerve cells to toxic assault in Lou Gehrig's disease 4Health News:Dr. Robert CJ Krasner Appointed to Vitals.com as Independent Advisor 2Health News:SAIC Awarded DIA Intelligence Analysis Contract 2Health News:TV in the Bedroom Is Not a Teen's Best Friend 2Health News:TV in the Bedroom Is Not a Teen's Best Friend 3Health News:Accuri Cytometers Announces Commercial Launch of Revolutionary Accuri C6 Flow Cytometer(TM) System 2Health News:Accuri Cytometers Announces Commercial Launch of Revolutionary Accuri C6 Flow Cytometer(TM) System 3Health News:Accuri Cytometers Announces Commercial Launch of Revolutionary Accuri C6 Flow Cytometer(TM) System 4
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
Medicine Products: