Navigation Links
Peregrine Pharmaceuticals Submits Clinical Protocol for New Phase II Trial of Bavituximab in Patients With Metastatic Breast Cancer
Date:10/22/2007

working with have solid experience in conducting mid and late stage cancer trials that adhere to FDA and international standards. We have been impressed to date by the professionalism of their operations, the efficiency of their patient recruitment infrastructure and their commitment to patient welfare."

Tumor response in this new study will be evaluated using Response Evaluation Criteria in Solid Tumors (RECIST) parameters. The trial is being conducted according to ICH and GCP guidelines.

According to the World Health Organization, metastatic breast cancer is the most commonly diagnosed cancer in women, and is second only to lung cancer as a leading cause of female cancer deaths. The National Cancer Institute estimates that 178,480 U.S. women will be diagnosed with cancer of the breast in 2007 and 40,460 women will die of the disease.

Bavituximab is a monoclonal antibody that binds to a phospholipid called phosphatidylserine that is normally located inside normal cells, but which becomes exposed on the outside of the cells that line the blood vessels of tumors, creating a specific target for anti-cancer treatments. Bavituximab is believed to help mobilize the body's immune system to destroy the blood vessels needed for tumor growth and spread. In a Phase lb trial in advanced cancer patients, bavituximab plus chemotherapy appeared to have a safety profile consistent with chemotherapy alone and showed positive signs of clinical activity, achieving objective response or disease stabilization in 50% of the evaluable patients. A protocol for a Phase ll trial of bavituximab in combination with the chemotherapy drugs paclitaxel and carboplatin in patients with metastatic breast cancer is currently undergoing regulatory review in India. A protocol for a Phase ll trial of bavituximab in combination with chemotherapy in patients with non-small cell lung cancer (NSCLC) is also under regulatory review in India. Bavituximab is in clinical trials in the U.S. i
'/>"/>

SOURCE Peregrine Pharmaceuticals, Inc.
Copyright©2007 PR Newswire.
All rights reserved

Page: 1 2 3 4

Related medicine technology :

1. Peregrine Pharmaceuticals Reports Positive Top-Line Results in Bavituximab Combination Therapy Trial in Advanced Cancer Patients
2. Positive Results Using Affitech-Identified Human Antibody That Blocks VEGF Binding to VEGF Receptor 2 in Preclinical Cancer Model Reported by Peregrine
3. Peregrine Pharmaceuticals Highlights Significant Advances in the Companys Clinical and Preclinical Cancer Programs Presented This Week at the AACR Annual Meeting
4. Data Presented at AACR Meeting Shows Peregrines Immunocytokine Fusion Proteins Reduce Growth of B-Cell Lymphoma Tumors by 85% in Preclinical Studies
5. Data Presented at AACR Meeting Show Peregrines Bavituximab Equivalent Can Generate Curative Immune Responses as Part of a Vaccine-Like Regimen in Preclinical Models of Aggressive Brain Cancer
6. Data Presented at AACR Meeting Shows Peregrines Selective Anti-VEGF Antibodies are as Effective as Avastin(R) in Preclinical Cancer Models
7. Inspiration Biopharmaceuticals Presents Data From Hemophilia Program at International Society On Thrombosis and Haemostasis (ISTH) Annual Meeting
8. BioSante Pharmaceuticals Announces New Findings for Potential Bird Flu Vaccine
9. Portola Pharmaceuticals Announces Positive Data from a Phase II Study of its Factor Xa Inhibitor at the XXI Congress of the International Society on Thrombosis and Haemostasis
10. Manhattan Pharmaceuticals Announces Results of Phase 2a Studies for Oral Oleoyl-estrone
11. Auxilium Pharmaceuticals to Present at the 2007 CEUT Emerging Growth Opportunities Conference
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/4/2015)... BioPharma Inc. (NASDAQ: ARRY ) today reported ... year ending June 30, 2015. Ron ... close of the Novartis-GSK transaction, Array now owns ... in Phase 3, with plans for regulatory submissions ... have accelerated our path to commercialization and provide ...
(Date:5/3/2015)... , May 4, 2015 A new ... and families to reduce asthma-related illness. ... that pharmacies in neighborhoods with high rates of ... controller medications compared to asthma rescue medications. ... living in poverty or with limited access to ...
(Date:5/1/2015)... 1, 2015 Hitachi Chemical Diagnostics, Inc. is ... launch of the ExoComplete™ 96-Well Plate Kit and ... for exosome collection to mRNA purification.  The products were ... Annual Meeting, April 23 – 26, 2015, in ... for research use only of molecular biology applications and ...
Breaking Medicine Technology:Array BioPharma Reports Financial Results For The Third Quarter Of Fiscal 2015 2Array BioPharma Reports Financial Results For The Third Quarter Of Fiscal 2015 3Array BioPharma Reports Financial Results For The Third Quarter Of Fiscal 2015 4Array BioPharma Reports Financial Results For The Third Quarter Of Fiscal 2015 5Array BioPharma Reports Financial Results For The Third Quarter Of Fiscal 2015 6Array BioPharma Reports Financial Results For The Third Quarter Of Fiscal 2015 7Array BioPharma Reports Financial Results For The Third Quarter Of Fiscal 2015 8Array BioPharma Reports Financial Results For The Third Quarter Of Fiscal 2015 9Array BioPharma Reports Financial Results For The Third Quarter Of Fiscal 2015 10New Study Suggests Prominent Role for Pharmacies In Reducing Asthma-related Illness 2New Study Suggests Prominent Role for Pharmacies In Reducing Asthma-related Illness 3New Products for Exosome Isolation to mRNA Purification 2
... NeurogesX, Inc. (Nasdaq: NGSX ), a biopharmaceutical ... announced that it has entered into a $20 million ... HTGC).  The loan agreement includes both a $5 million ... term loan. Proceeds are expected to be ...
... Aug. 8, 2011 Global Health Ventures Inc. ... on sublingual drug delivery announced today that their August ... and CEO, is available for on-demand viewing. ... watch event now" button. Their presentation will ...
Cached Medicine Technology:NeurogesX, Inc. Secures $20 Million Debt Facility 2NeurogesX, Inc. Secures $20 Million Debt Facility 3NeurogesX, Inc. Secures $20 Million Debt Facility 4Global Health Ventures August 4th Investor Presentation Now Available for On-demand Viewing at RetailInvestorConferences.com 2
(Date:5/4/2015)... “ Food Cost Calculator ” was featured ... a look at the latest and coolest applications on the ... of AppWatch and technology expert, conducted the app review and ... manage and efficiently calculate food costs. , The restaurant industry ... the industry has an estimated 1.8 trillion dollar impact on ...
(Date:5/4/2015)... (PRWEB) May 04, 2015 ... just released the first-ever congenital heart disease ... Catheterization Laboratory (PCCL) accreditation. Driven by the ... are a comprehensive review of interventional procedures ... heart disease. , “The ACE CHD Standards ...
(Date:5/4/2015)... “St. Louis has long represented opportunity and ... so it is the perfect place for Zerorez to ... Litalien, Chief Development Officer for Zerorez. “We have ... provide veterans with a $10,000 discount on our franchise ... a number of Military Veterans in its ranks including ...
(Date:5/4/2015)... (PRWEB) May 04, 2015 Sara Soulati, ... physician practice management firm in Los Angeles associated with ... the patent-pending status of The Sara Soulati Health For ... in 2010, is a lifestyle modification and disease prevention ... 2015 to the U. S. Patents and Trademarks Office ...
(Date:5/3/2015)... Birmingham, Lake Orion, Clarkston, Metamora, Michigan (PRWEB) May 03, 2015 ... . She has worked to enhance the well being of ... as a generalist in a hospital, followed by providing care for ... I worked with as an Adult Nurse Practitioner began wondering if ... coupled with the birth of my own children with my mentor ...
Breaking Medicine News(10 mins):Health News:An Application to Manage a Successful Restaurant Was Featured on NewsWatch Television 2Health News:Accreditation for Cardiovascular Excellence (ACE) Publishes New Standards for Pediatric and Adult Congenital Cardiac Catheterization Laboratories 2Health News:Zerorez® Creates “Gateway” for Veterans--Announces VetFran Participation. Plans Expansion into the St. Louis Region. 2Health News:Zerorez® Creates “Gateway” for Veterans--Announces VetFran Participation. Plans Expansion into the St. Louis Region. 3Health News:CEO Sara Soulati Announces Patent-Pending Designation For The Sara Soulati Health For Life Program 2Health News:Women's Excellence In Midwifery Welcomes Barbara Crone 2
... thirty poor women of the fishing community, living on Chennai’s ... The 1994 Transplant of Human Organ Act ... to donate kidneys for transplantation. However a recent report from ... that several leading hospitals in the state encouraged the economically ...
... 50% of sexually active gay men in the UK had unprotected ... the 2005 Gay Men’s Sex Survey//, Consuming Passions, which has been ... of gay men in the UK are unaware of their own ... not disclosed their HIV infection status. ,The study ...
... on 4,000 pregnant women one-fifth of them had to undergo ... failed//. Researchers found that obesity impairs the ability of the ... and deliver the baby. ,In a study of ... overweight women had to undergo an emergency Caesarean Section birth ...
... the Virginia Tech sure had the whole world reaching out ... //An incident unbelievable, the shooting had aftermaths throughout the world. ... family of the people who died at the university. ... to come to term with the whole incident. It will ...
... fetuses could survive. And they have, one in thirty. Such ... hospitals. // ,Most of these babies with ... and all lived for no more than a few hours, ... Obstetrics and Gynaecology study. ,About 190,000 abortions take ...
... one is aware that strawberries are good for health. ... form makes it healthier. // ,While exploring ... from Thailand and the US discovered that treating the ... capacity and free radical scavenging activity within the fruit. ...
Cached Medicine News:Health News:Kidney Trade: Curbing the Sale 2Health News:Kidney Trade: Curbing the Sale 3Health News:One-fifth of Obese Women Undergo Caesarean Due to Uterus Failure 2Health News:Support for Trauma and Grief 2Health News:Aborted Babies Survive, a British Study Says 2
Fine .12mm Tip With 5mm Platform; In Titanium....
Angled tip, 0.3mm triangular grasping tips; In Titanium....
... addition to any Trial ... Trial Frame provides a ... controls for quick, easy ... high-quality materials, and precision ...
... The Ultramatic Rx Master is ... years of reliable service and ... that measurably improve procedures. It ... need and want most, including ...
Medicine Products: