Navigation Links
Peregrine Pharmaceuticals Doses First Patient in Clinical Trial of Bavituximab in HCV Patients Co-Infected With HIV
Date:10/10/2007

30% of all HIV-infected patients. Co-infected patients have been shown to have a lower response to current HCV treatment regimens and the adverse effects of these regimens can be especially problematic for some HIV patients.

Bavituximab is a monoclonal antibody in a new class of anti-phosphotidylserine (PS) immunotherapeutics that targets and binds to cellular components that are normally not present on the outside of cells, but which become exposed on certain virally infected cells and on the surface of enveloped viruses, including both HCV and HIV. Bavituximab helps stimulate the body's immune defenses to destroy both the virus particles and the infected cells. Since bavituximab's PS target comes from the host and not the virus, bavituximab may be less susceptible to the development of anti-viral resistance. Peregrine has completed two bavituximab Phase l monotherapy clinical trials in patients with chronic HCV infection. In these trials, the drug appeared safe and well tolerated with encouraging signs of anti-viral activity.

About Peregrine Pharmaceuticals

Peregrine Pharmaceuticals, Inc. is a biopharmaceutical company with a portfolio of innovative product candidates in clinical trials for the treatment of cancer and hepatitis C virus (HCV) infection. The company is pursuing three separate clinical programs in cancer and HCV infection in the U.S. and India with its lead product candidates bavituximab and Cotara(R). Peregrine also has in-house manufacturing capabilities through its wholly owned subsidiary Avid Bioservices, Inc. (http://www.avidbio.com), which provides development and bio-manufacturing services for both Peregrine and outside customers. Additional information about Peregrine can be found at http://www.peregrineinc.com.

Safe Harbor Statement: Statements in this press release which are not purely historical, including stat
'/>"/>

SOURCE Peregrine Pharmaceuticals, Inc.
Copyright©2007 PR Newswire.
All rights reserved

0

GOOD

Page: 1 2 3 4

Related medicine technology :

1. Peregrine Pharmaceuticals Reports Positive Top-Line Results in Bavituximab Combination Therapy Trial in Advanced Cancer Patients
2. Positive Results Using Affitech-Identified Human Antibody That Blocks VEGF Binding to VEGF Receptor 2 in Preclinical Cancer Model Reported by Peregrine
3. Peregrine Pharmaceuticals Highlights Significant Advances in the Companys Clinical and Preclinical Cancer Programs Presented This Week at the AACR Annual Meeting
4. Data Presented at AACR Meeting Shows Peregrines Immunocytokine Fusion Proteins Reduce Growth of B-Cell Lymphoma Tumors by 85% in Preclinical Studies
5. Data Presented at AACR Meeting Show Peregrines Bavituximab Equivalent Can Generate Curative Immune Responses as Part of a Vaccine-Like Regimen in Preclinical Models of Aggressive Brain Cancer
6. Data Presented at AACR Meeting Shows Peregrines Selective Anti-VEGF Antibodies are as Effective as Avastin(R) in Preclinical Cancer Models
7. Inspiration Biopharmaceuticals Presents Data From Hemophilia Program at International Society On Thrombosis and Haemostasis (ISTH) Annual Meeting
8. BioSante Pharmaceuticals Announces New Findings for Potential Bird Flu Vaccine
9. Portola Pharmaceuticals Announces Positive Data from a Phase II Study of its Factor Xa Inhibitor at the XXI Congress of the International Society on Thrombosis and Haemostasis
10. Manhattan Pharmaceuticals Announces Results of Phase 2a Studies for Oral Oleoyl-estrone
11. Auxilium Pharmaceuticals to Present at the 2007 CEUT Emerging Growth Opportunities Conference
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/9/2008)...s and Marketing Efforts to Accelerate ... PARK, Calif., Oct. 9 /- Evalve, Inc.... percutaneous repair of cardiac valves,has expand... appointment of,Sean Cleary as senior vice preside...ardson, as vice president of sales., "The additio...
(Date:10/9/2008)...FirstCall/ -- Diamyd Medical reports,that the worl...and Journal,of Medicine, has published an article ...d(R) diabetes vaccine for type 1 diabetes., (Logo...7194 ), The article is now available on the jour... in print on October 30. It presents the,results o...
(Date:10/8/2008)...atments for Spinal Cord, Other Nerve,Injuries -, ...protein that enables,nerve cells to communicate wi...developing nervous system. Research into how that ...rve cells may provide a basis for eventual,treatme...ous system,including spinal cord injury., "This ...
(Date:10/8/2008)...sts Expand Testing Using Cellular ..., Oct. 8 /- Wild Blueberry antioxidan...lts from a new study,showing Wild Blueberries outp...ke apples, bananas, red grapes and strawberries in...ctivity (CAA) assay. New research,published in the...
Breaking Medicine Technology:Evalve Expands Executive Leadership Team 2Evalve Expands Executive Leadership Team 3Diamyd(R) Study Published in Prestigious New England Journal of Medicine 2Diamyd(R) Study Published in Prestigious New England Journal of Medicine 3Diamyd(R) Study Published in Prestigious New England Journal of Medicine 4Protein Shown to Play a Key Role in Normal Development of Nervous System 2Protein Shown to Play a Key Role in Normal Development of Nervous System 3Wild Blueberries Take Top Spot in New Antioxidant Research Study 2Wild Blueberries Take Top Spot in New Antioxidant Research Study 3SportCoatings 3B The North American Booster Club Association 28NABCA 29 3B the Coatings Specialist Group New Booster Program Goes High Tech With Invi 149 1SportCoatings 3B The North American Booster Club Association 28NABCA 29 3B the Coatings Specialist Group New Booster Program Goes High Tech With Invi 149 2SportCoatings 3B The North American Booster Club Association 28NABCA 29 3B the Coatings Specialist Group New Booster Program Goes High Tech With Invi 149 3Weight Loss Surgeries Extend Lives 152 1Weight Loss Surgeries Extend Lives 152 2Weight Loss Surgeries Extend Lives 152 3Weight Loss Surgeries Extend Lives 152 4NYC area 1st 3A Morgan Stanley Childrens Hospital performs transcatheter pulmonary valve replacement 150 1NYC area 1st 3A Morgan Stanley Childrens Hospital performs transcatheter pulmonary valve replacement 150 2Restless legs syndrome affects nearly 2 percent of US UK children 135 1Restless legs syndrome affects nearly 2 percent of US UK children 135 2Restless legs syndrome affects nearly 2 percent of US UK children 135 3
... release broad range of clinical data on leading,d..., 2007 /PRNewswire-FirstCall/ -- Boston,Scientific...ompany,s major events and press announcements at t...CR), which will runs from May 22,to 25 in Barcelon...everal of our clinical,trials and registries, addi...
..., Calif.--(BUSINESS WIRE)--May 15, 2007 - Syntheti...ounced positive data from,a statistical analysis o... with traumatic brain injury. In line with prelimi...tistical results,confirmed that the primary endpoi...ompared with baseline was met. Data also show a,de...
Other Medicine Technology:Boston Scientific Announces Schedule for EuroPcr 2007 2Boston Scientific Announces Schedule for EuroPcr 2007 3Boston Scientific Announces Schedule for EuroPcr 2007 4Boston Scientific Announces Schedule for EuroPcr 2007 5Positive Statistical Analysis from Synthetic Blood's Oxycyte,Traumatic Brain Injury Trial Indicates Achievement of Primary,Endpoint 2Positive Statistical Analysis from Synthetic Blood's Oxycyte,Traumatic Brain Injury Trial Indicates Achievement of Primary,Endpoint 3
(Date:10/14/2008)... Also debuts TMR,09 campaign, IRVINE, Calif., O...poration (Pink Sheets: CGCP), a global leader of i...nd the market leader of surgical products for,tran...educational symposium,yesterday in conjunction wit...rapeutics (TCT) meeting in Washington, D.C., The ...
(Date:10/14/2008)... more than 500 accounts Company opening new PROMUS...ICK, Mass., Oct. 14 /PRNewswire-FirstCall/ -- Bost...unced estimated U.S. market shares for,September f...liminary data,from Millennium Research Group (MRG)...he healthcare sector., Based on the MRG data, the...
(Date:10/14/2008)... Leading Supplemental Insurance Company Encour... Employee Benefits , Chic...e , a leading provider of supplemental insurance, ...time to review employee benefits and recommends ,V...to help retain employees. These programs can be a ...
(Date:10/14/2008)...ctober 14 /PRNewswire/ -- Researchers at the Insti... started work on a 3.5 year,project to develop a n...hemical vapour deposition) diamond manufactured by...he field of CVD diamond synthesis and its,applicat...uld open up a raft of new,application areas in, fo...
Breaking Medicine News(10 mins):Health News:Cardiogenesis Announces Successful Educational Symposium Targeted at Cardiologists at the TCT Meeting in Washington, D.C. 2Health News:Cardiogenesis Announces Successful Educational Symposium Targeted at Cardiologists at the TCT Meeting in Washington, D.C. 3Health News:Cardiogenesis Announces Successful Educational Symposium Targeted at Cardiologists at the TCT Meeting in Washington, D.C. 4Health News:Boston Scientific Announces Drug-Eluting Stent Market Share Estimates for September and Third Quarter 2Health News:Boston Scientific Announces Drug-Eluting Stent Market Share Estimates for September and Third Quarter 3Health News:Boston Scientific Announces Drug-Eluting Stent Market Share Estimates for September and Third Quarter 4Health News:Combined Insurance Reports that Voluntary Programs Can Offer Employers a Cost Effective Way to Offer Benefits and Help Retain Employees 2Health News:Combined Insurance Reports that Voluntary Programs Can Offer Employers a Cost Effective Way to Offer Benefits and Help Retain Employees 3Health News:Combined Insurance Reports that Voluntary Programs Can Offer Employers a Cost Effective Way to Offer Benefits and Help Retain Employees 4Health News:Combined Insurance Reports that Voluntary Programs Can Offer Employers a Cost Effective Way to Offer Benefits and Help Retain Employees 5Health News:Novel Solid-State Laser Design Based on Synthetic Diamond From Element Six Opens up New Applications 2Health News:Novel Solid-State Laser Design Based on Synthetic Diamond From Element Six Opens up New Applications 3Health News:Novel Solid-State Laser Design Based on Synthetic Diamond From Element Six Opens up New Applications 4
...ed the G8 summit of the world's top industrialised..., warning that inaction would be costly. In a st...mm in Germany, Ban said the eight participating na... long-term global framework to tackle climate chan...
... womens insecurity about their body and their body...J. They believe that women should be warned about...lternative solutions to concerns about the appeara...hould be developed. More and more women are said ...
...s regularly investigated and debated for its impac... disease. Among its complex effects on the body, c... insulin and uric acid levels on a short-term basi...s suggest that coffee consumption may affect the r...
...ely low frequency electromagnetic fields, suggests...l and Environmental Medicine. The findings are ba... were monitored for 30 years. The researchers opt..., because railway workers in Switzerland tend to c...
Other Medicine News:Health News:Cosmetic Genital Surgery may Be Fuelling Womens Insecurity About Their Bodies 2Health News:Four Cups of Coffee a Day may Cut Down the Risk of Gout 2Health News:Four Cups of Coffee a Day may Cut Down the Risk of Gout 3
...MiniCorr Digital Hand-Held Pulse Oximeter provides... neonate to adult. The device is battery or AC po...ible and audible alarm signals, and an infrared li...r boot is also available for added protection. Th...
The FingerPrint Sleep Hand-Held Pulse Oximeter with built-in Summary Printer was specifically designed for sleep screening studies in the sleep lab, clinical environment, or home. With its easy-to-u
The BCI 3180 Pulse Oximeter is a cost-effective, stand-alone monitor that delivers fast, reliable SpO 2 pulse rate and pulse strength measurements of patients from neonate to adult. This AC or batt
...U.S. Food and Drug Administration (FDA) has grante...ens (IOL) for cataract patients with and without p...ry apodized diffractive technology to give patient...te and distance) that greatly increases their inde...
Medicine Products: