Navigation Links
Pepscan Therapeutics Presents Protein Mimicry Platform for the Discovery of anti-GPCR Antibodies at International Antibody Conference
Date:12/6/2011

, like phage display libraries or hybridoma generation procedures.

Dr. Schwamborn stated: "Our approach has proven to be successful and the fact that we have the possibility to tailor antibodies to certain GPCR domains enables us to engineer antibodies which fulfill certain biological requirements. The immunogen design concept for mimicking extracellular domains of discontinuous epitopes might be also applicable to other important target classes like ion channels".

About Pepscan Therapeutics

Pepscan Therapeutics is a privately held company based in Lelystad, The Netherlands. Pepscan is using its proprietary high throughput CLIPS protein mimicking technology for the development of novel constrained therapeutic peptides and immunogens. Besides its pipeline of proprietary anti-GPCR monoclonal antibody products, Pepscan has various ongoing collaborations with leading pharmaceutical and biotech companies to develop novel therapeutics based on the proprietary CLIPS technology.

About CLIPS

CLIPS (Chemical LInkage of Peptides onto Scaffolds) is a technology to present one or more peptides in a structurally constrained configuration. These molecules behave as functional mimics of structurally complex protein domains. CLIPS therapeutic peptides have been shown to exert improved activity and stability. CLIPS peptides are also used as superior immunogens for antibody generation against disease relevant protein targets. This is especially valuable in the case of proteins that are inaccessible as recombinant proteins, such as GPCRs.

http://www.pepscan.com 


'/>"/>
SOURCE Pepscan Therapeutics BV
Copyright©2010 PR Newswire.
All rights reserved

0

GOOD

Page: 1 2

Related medicine technology :

1. Pepscan Therapeutics Strengthens Management Team
2. ViroPharma and Halozyme Therapeutics Announce Positive Data From Initial Phase 2 Assessment of Subcutaneous Cinryze® (C1 esterase inhibitor [human]) with Hyaluronidase (rHuPH20)
3. Echo Therapeutics Announces Pricing of $5.4 Million Registered Direct Equity Financing
4. FDA Sets April 24, 2012 as PDUFA Goal Date for Cell Therapeutics Resubmitted Pixantrone New Drug Application
5. GiiResearch.com: Polycystic Ovarian Syndrome (PCOS) Therapeutics - Market to Witness Static Growth Until 2018
6. Novelos Therapeutics Prices $5.9 Million Public Offering
7. Unigenes Proprietary Peptelligence™ Platform Used to Commence Cara Therapeutics Phase 1 Clinical Trial of Oral Novel Peripherally-Acting Kappa Opioid Agonist
8. Antiviral Therapeutics - Technologies, Markets and Companies
9. Pain Management Therapeutics Market to 2017 - Price Competition to Intensify Following Patent Expiries of Lyrica and Cymbalta
10. Cara Therapeutics Initiates Phase I Study with Oral Formulation of Novel Peripherally-Acting Kappa Opioid Agonist
11. Amsterdam Molecular Therapeutics Receives Orphan Designation in the European Union for Hemophilia B Gene Therapy
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/24/2013)... 24, 2013  Sinovac Biotech Ltd. (NASDAQ: ... products in China , announced ... of Sinovac, obtained the Certificate of Good Manufacturing ... China State and Food Administration (CFDA) for its ... and its Changping filing and packaging facility. The ...
(Date:5/23/2013)... DIEGO y PARÍS, 24 de mayo ... VOLC ), un destacado desarrollador y fabricante de ... mejorar la diagnosis y tratamiento de la enfermedad ... preliminares del ensayo ADVISE ( Ad enosine ... E valuation) II durante la sesión de ...
(Date:5/23/2013)... Hearing health affects a man,s lifestyle, and if ... and professionally engaged, he should address any hearing loss he ... Better Hearing Institute (BHI) is delivering to men ... Week , which leads up to and includes Father,s Day. ... through June 16. To help men address ...
Breaking Medicine Technology:Sinovac Beijing Obtains China GMP Certificate Under the New GMP Guidelines 2Sinovac Beijing Obtains China GMP Certificate Under the New GMP Guidelines 3Volcano anuncia los resultados preliminares del estudio ADVISE II y su inclusión en el ensayo SYNTAX2 2Volcano anuncia los resultados preliminares del estudio ADVISE II y su inclusión en el ensayo SYNTAX2 3Volcano anuncia los resultados preliminares del estudio ADVISE II y su inclusión en el ensayo SYNTAX2 4Volcano anuncia los resultados preliminares del estudio ADVISE II y su inclusión en el ensayo SYNTAX2 5Volcano anuncia los resultados preliminares del estudio ADVISE II y su inclusión en el ensayo SYNTAX2 6Men Who Want to Stay Active, Feel Younger, and Remain Socially and Professionally Engaged Should Address Hearing Loss, BHI Advises 2Men Who Want to Stay Active, Feel Younger, and Remain Socially and Professionally Engaged Should Address Hearing Loss, BHI Advises 3Men Who Want to Stay Active, Feel Younger, and Remain Socially and Professionally Engaged Should Address Hearing Loss, BHI Advises 4
... a world-leading developer, manufacturer and marketer of innovative medical ... following a review of current conditions in the credit ... secured term loans originally entered into on December 22, ... developer and marketer of innovative medical technologies. With four ...
... March 17, 2011 Pharmaceutics International Inc. (Pii), ... announced the appointment of Rampurna Prasad Gullapalli as ... is responsible for providing strategic scientific and technical ... and novel drug delivery technologies for Pii,s contract ...
Cached Medicine Technology:ConvaTec Healthcare Postpones Plans To Refinance Secured Term Loans 2ConvaTec Healthcare Postpones Plans To Refinance Secured Term Loans 3Pharmaceutics International Inc. (Pii) Announces Appointment of Rampurna Prasad Gullapalli, Ph.D. as Vice President of Drug Delivery Technologies 2
(Date:5/24/2013)... Los Angeles, CA (PRWEB) May 24, 2013 ... is to present the 3rd Annual EB-5 Investment Summit: ... 2013. The Dealmakers Conference will focus on exploring alternative ... provide the latest market, legal and economic information, and ... legal professionals within the EB-5 industry. , "Our ...
(Date:5/24/2013)... 24, 2013 Dwell Media LLC ... Huff as Executive Vice President of Digital for Dwell ... which represented a large portion of Yahoo's global media ... Dwell develops a fully-integrated commerce unit to launch in ... monetizing digital content for leading firms in Silicon Valley. ...
(Date:5/24/2013)... 2013 Mike Stoler believes that there ... business people in New York. That’s why he ... on CUNY TV. And that’s why he invited ... Associates, LLP (ENTA)—the largest single specialty practice in the ... allergy and audiology specialists and sub-specialists service communities throughout ...
(Date:5/24/2013)... 24 (HealthDay News) -- Low-income, minority parents have ... and are more open to vaccinating their daughters ... small new study contends. Conversely, white, middle-class ... for their daughters, according to researchers from the ... Americans will get an HPV-related cancer each year, ...
(Date:5/24/2013)... the National Institutes of Health, Stevens Johnson Syndrome (SJS) is ... skin and mucous membranes. SJS occurs most commonly in ... In the early stages SJS presents flu-like symptoms, including ... affects the mucous membranes such as the eyes, mouth (lips ... causes conjunctivitis (pink eye). Inflammation of the mouth causes ...
Breaking Medicine News(10 mins):Health News:Brian Su Organizes 3rd Annual EB-5 Investment Conference in Long Beach, California 2Health News:Yahoo Commerce Head Joins Leadership at Dwell Media 2Health News:Robert Glazer, Chief Executive Officer of ENT and Allergy Associates, LLP®, Talks About the Business of Succeeding in New York 2Health News:Robert Glazer, Chief Executive Officer of ENT and Allergy Associates, LLP®, Talks About the Business of Succeeding in New York 3Health News:Robert Glazer, Chief Executive Officer of ENT and Allergy Associates, LLP®, Talks About the Business of Succeeding in New York 4Health News:Low-Income, Minority Parents More Open to HPV Vaccine for Girls, Study Says 2Health News:Personal Injury Law Firm Issues New Infographic Detailing a Potential Link Between Stevens Johnson Syndrome and Common Children’s Medicines 2Health News:Personal Injury Law Firm Issues New Infographic Detailing a Potential Link Between Stevens Johnson Syndrome and Common Children’s Medicines 3
... UCSF Medical Center patients, behind the scenes a family of ... new automated hospital pharmacy, believed to be the nation,s most ... and track medications with the goal of improving patient safety. ... 350,000 doses of medication prepared during the system,s recent phase ...
... tumor growth, and naturally mounts an anti-cancer defense. Dendritic ... present them to T cells, and those "primed" T ... cells. In recent years, researchers have attempted to capitalize ... namely, by generating a pool of tumor antigen-pulsed DCs ...
... Fla. (Mar. 07, 2011) Transplanting stem ... menstrual blood cells may offer future therapeutic benefit ... amyotrophic lateral sclerosis (ALS), says a team of ... Department of Neurosurgery and Brain Repair and collaborators ...
... By Steven Reinberg HealthDay Reporter , SUNDAY, March ... day offer a safe way to detect Down syndrome during ... blood test identified a gene mutation associated with Down syndrome ... "Down syndrome is a common birth defect, with one Down ...
... aging adults soon will face decisions about where and how ... including nursing homes and assisted-living facilities, are costly and require ... researchers have found that a new strategy for long-term care ... health outcomes. Adults want to remain healthy and ...
... easy? Then why didn,t anyone think of it a long ... at the right time," says Annette Rttger, physicist at the ... her scientific team managed to do something that was previously ... the measurement of short-lived radioactive thoron. Thoron measuring instruments from ...
Cached Medicine News:Health News:New UCSF robotic pharmacy aims to improve patient safety 2Health News:New UCSF robotic pharmacy aims to improve patient safety 3Health News:Transplanting umbilical cord and menstrual blood-derived stem cells offer hope for disorders 2Health News:Transplanting umbilical cord and menstrual blood-derived stem cells offer hope for disorders 3Health News:Transplanting umbilical cord and menstrual blood-derived stem cells offer hope for disorders 4Health News:Noninvasive Test May Identify Down Syndrome Early On 2Health News:Aging in place preserves seniors' independence, reduces care costs, MU researchers find 2Health News:Accurate measurement of radioactive thoron possible at last 2
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
Medicine Products: