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Patients Treated with Risperidone Long-Acting Injection had a Significantly Longer Time to Relapse Compared to Quetiapine in International Clinical Study
Date:5/6/2008

Evaluation of the factors interfering with drug treatment compliance among Brazilian patients with schizophrenia. Rev Bras Psiquiatr 2005;27:78-84.

(3)Relapse diagnosed if subjects met any of the following criteria on 2 consecutive evaluations conducted 3-5 days apart: Psychiatric hospitalization; Increase in level of care necessary AND .25 percent increase in PANSS total score from baseline or an increase of 10 points if the baseline score was .40; Significant clinical deterioration defined as a CGI-C score of 6 (much worse); Deliberate self-injury; Emergence of clinically significant suicidal or homicidal ideation; Violent behavior resulting in significant injury to another person or property; Exceeding the registered dose of the drug

(4)Hogarty GE, Schooler NR, Ulrich R et al. Arch Gen Psychiatry 1979;36:1283-94

(5)Medori R, Wapenaar R, de Arce R et al. Relapse Prevention and Effectiveness in Schizophrenia with Risperidone Long-Acting Injectable (RLAI) Versus Quetiapine. Poster presented at 161st Annual American Psychiatric Association Meeting, 2008, Washington, USA

(6)In this study, a small number of patients were randomized to aripiprazole for exploratory purposes only. The descriptive efficacy and safety analysis of these patients will be presented separately.

(7)Concetta C, Mao L, Kosma C et al., Evaluation of effectiveness measures for patients with schizophrenia who initiated therapy with risperidone long- acting injectable, presented at the 161st Annual Meeting of the American Psychiatry Association (APA), Washington, DC.


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