Navigation Links
Patients Taking VIMOVO(TM) Showed a Decrease in Incidence of NSAID-Associated Ulcers
Date:10/19/2009

PHILADELPHIA, Oct. 19 /PRNewswire-FirstCall/ -- AstraZeneca (NYSE: AZN) and POZEN Inc. (Nasdaq: POZN) today announced pivotal data from two POZEN clinical trials that were presented at the American College of Rheumatology (ACR) 2009 Annual Scientific Meeting in Philadelphia, PA.

The data demonstrated that patients at risk for developing NSAID-associated gastric ulcers taking VIMOVO(TM) (naproxen/esomeprazole magnesium, formerly known as PN 400) experienced significantly fewer endoscopically confirmed gastric ulcers (GU) compared with patients taking enteric-coated (EC) naproxen (500 mg) alone. Data from study PN400-301 showed a 4.1% incidence of GU in patients taking VIMOVO, compared to 23.1% among patients taking EC naproxen (p<0.001). Study PN400-302 showed a 7.1% incidence of GU among patients taking VIMOVO, compared to 24.3% with EC naproxen (p<0.001).

VIMOVO is a fixed-dose combination of enteric-coated naproxen, a non-steroidal anti-inflammatory drug (NSAID) and immediate release esomeprazole, a proton pump inhibitor (PPI), under investigation for the treatment of the signs and symptoms of osteoarthritis (OA), rheumatoid arthritis (RA) and ankylosing spondylitis (AS) in patients who are at risk of developing NSAID-associated gastric ulcers.

"These results provide new information about VIMOVO and the incidence of NSAID-induced endoscopically confirmed gastric ulcers in patients with osteoarthritis," said Marc C. Hochberg, M.D., M.P.H., professor of medicine and head of the Division of Rheumatology and Clinical Immunology, University of Maryland School of Medicine in Baltimore, and co-principal investigator for the study. "If approved, VIMOVO will provide arthritis patients at risk for NSAID associat
'/>"/>

SOURCE AstraZeneca
Copyright©2009 PR Newswire.
All rights reserved

0

GOOD

Page: 1 2 3 4 5

Related medicine technology :

1. ULORIC(R) (febuxostat) Demonstrated Efficacy for Management of Hyperuricemia in Patients with Gout
2. U.S. Food and Drug Administration Approves CRESTOR(R) for Use in Pediatric Patients With Heterozygous Familial Hypercholesterolemia
3. Data from Jazz Pharmaceuticals First Phase III Study of Sodium Oxybate in Patients With Fibromyalgia to be Presented at Upcoming Conferences
4. New Data Showed Type 2 Diabetes Patients Experienced Greater Blood Sugar Reductions when Treated with ACTOplus met(R) (pioglitazone HCl and metformin HCl) as Initial Therapy Compared to Either Component Alone
5. Breast Cancer Survivors and Patients Encouraged to Have Medical History Readily Available
6. Curemark Enrolls First Patients in Phase III Clinical Trials for Autism Treatment
7. Fresenius Medical Care, N.A. Has Selected VitalRemedyMDs VitalProteinRx(TM) As Its Bar of Choice for Protein Replacement in Dialysis Patients
8. Results Published In Journal of Cystic Fibrosis Confirm CREON(R) (pancrelipase) Delayed-Release Capsules Improves Fat Absorption in Patients With Cystic Fibrosis
9. Breast-Specific Gamma Imaging Proves Cost-Effective for Pre-Surgical Planning of Patients with Known Cancer Diagnosis
10. Latest Content Release for The T SystemEV EDIS Supports Clinicians in Providing Quality Care for H1N1 Patients
11. Outcomes Registry in Heart Attack Patients to Generate Numerous Studies; Data Quality Ensured Through Velos Clinical Research Management System
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/23/2013)... SAN DIEGO , May 23, 2013 /PRNewswire/ ... the prostate cancer treatment continuum was highlighted prominently ... the American Urological Association (AUA), in San Diego.  ... invasive high intensity focused ultrasound (HIFU) technology, the ... localize disease, and for urologists to consider minimally ...
(Date:5/23/2013)... 2013  Texas, premier physician associations today announced the ... tools they need to provide demonstrably better and more ... marketplace. "I am confident the Physician Services ... Stephen L. Brotherton , MD, president ... doctors are determined to make health care ...
(Date:5/23/2013)... May 23, 2013   Direct to implant, ... is an appropriate option for many women with ... reduce their breast cancer risk, or with breast ... process and a second surgery to insert permanent ... same surgery as mastectomy can be a medically ...
Breaking Medicine Technology:Need for Image Guided Minimally Invasive Ablative Treatments Featured Prominently at American Urological Association (AUA) Annual Meeting 2Need for Image Guided Minimally Invasive Ablative Treatments Featured Prominently at American Urological Association (AUA) Annual Meeting 3Need for Image Guided Minimally Invasive Ablative Treatments Featured Prominently at American Urological Association (AUA) Annual Meeting 4Need for Image Guided Minimally Invasive Ablative Treatments Featured Prominently at American Urological Association (AUA) Annual Meeting 5Need for Image Guided Minimally Invasive Ablative Treatments Featured Prominently at American Urological Association (AUA) Annual Meeting 6TMA Launches Physician Services Organization for Patient Care 2TMA Launches Physician Services Organization for Patient Care 3TMA Launches Physician Services Organization for Patient Care 4Direct to Implant ("One Step") Mastectomy Breast Reconstruction Reduces Number of Surgeries and Time to Final Cosmetic Results 2Direct to Implant ("One Step") Mastectomy Breast Reconstruction Reduces Number of Surgeries and Time to Final Cosmetic Results 3
... Inc. ("Senesco" or the "Company") (Amex: SNT ... Inc. (The Woodlands, TX) ("VGXI") to,supply the plasmid ... Factor 5A gene and siRNA against Factor 5A., ... vivo results,using its combination siRNA and plasmid against ...
... Continuing Education Newsletter Series for Healthcare ... ... is a serious condition that causes disease with a wide spectrum ... can occur in up to 20% of patients who develop an ...
Cached Medicine Technology:Senesco Chooses VGXI to Produce Factor 5A Plasmid 2Senesco Chooses VGXI to Produce Factor 5A Plasmid 3Current Concepts in Clostridium difficile Infection: A Focus on Recurrent Disease 2
(Date:5/24/2013)... 2013 Amirsys today announces the release ... for instructors and students. Instructors can use the new ... learning plan templates, targeted reading assignments, and customized instructions. ... assessment questions, 5,000 searchable anatomy glossary terms, and easier ... 2.0 is the first gross anatomy resource to ...
(Date:5/24/2013)... myofibromatosis (IM)a disorder characterized by multiple tumors involving the ... according to researchers from the Icahn School of Medicine ... American Journal of Human Genetics , may lead to ... the only current treatment option is repeated surgical removal ... that develops in infancy or even in utero and ...
(Date:5/24/2013)... May 24, 2013 Mike Stoler believes ... most successful business people in New York. That’s ... airs weekly on CUNY TV. And that’s why ... and Allergy Associates, LLP (ENTA)—the largest single specialty practice ... nose, throat, allergy and audiology specialists and sub-specialists service ...
(Date:5/24/2013)... 6Webs.com has educated thousands of buyers on what ... monitoring provider. The easy to read reviews and ... prefer for unbiased and impartial home security reviews. 6Webs.com ... wireless home security system providers in the nation. The ... of key factors including reliability, technology and equipment. ...
(Date:5/24/2013)... May 24, 2013 The Dictation Source ... base of clients. As a result of its National ... presence in 20 states around the nation. , Since ... transcription services to the healthcare industry . Dictation Source ... use their years of clinical work experience to provide ...
Breaking Medicine News(10 mins):Health News:Amirsys AnatomyOne 2.0 Delivers Personalized Learning Plans 2Health News:Researchers identify first drug targets in childhood genetic tumor disorder 2Health News:Robert Glazer, Chief Executive Officer of ENT and Allergy Associates, LLP®, Talks About the Business of Succeeding in New York 2Health News:Robert Glazer, Chief Executive Officer of ENT and Allergy Associates, LLP®, Talks About the Business of Succeeding in New York 3Health News:Robert Glazer, Chief Executive Officer of ENT and Allergy Associates, LLP®, Talks About the Business of Succeeding in New York 4Health News:2013 Best Wireless Security System Providers Reported by 6Webs.com 2Health News:The Dictation Source Signs Two National Hospital Chains 2Health News:The Dictation Source Signs Two National Hospital Chains 3
... to Visit Washington, D.C., and Meet with Elected Officials, ... will travel to Washington, D.C., this April 1 to ... of the,Americans with Disabilities Act, support for epilepsy public ... Serwik, 7, is one of 50 young people ...
... Visit Washington, D.C., and,Meet with Elected Officials, ... Nicklaus Schliesmann of Holmen will travel to Washington,D.C., ... and gain their,support for restoration of the Americans ... and more research toward a cure for,epilepsy., ...
... D.C., and Meet with Elected Officials, WASHINGTON, March ... travel to Washington, D.C., this April 1 to meet ... the,Americans with Disabilities Act, support for epilepsy public health,programs ... Smith, 15, is one of 50 young people with ...
... Corporation,(NYSE: STE ) today announced that its ... to $300 million in shares of STERIS common ... as of,February 29, 2008. This share repurchase authorization ... remaining. Through March,13, 2008, the Company has repurchased ...
... in Handling Credit ... Fraud, ... he has reached a settlement with TransUnion over his,lawsuit against the credit ... is the first of six credit reporting companies and banks,which Drew has ...
... LINTHICUM, Md., March 13 Dialysis Corporation,of America ... that it will begin,hosting conference calls in conjunction ... The conference call will he held,Friday morning, March ... interested may dial in at 800-750-4984 using pass-code ...
Cached Medicine News:Health News:Delaware Youth Named National Epilepsy Spokesperson 2Health News:Wisconsin Youths Named National Epilepsy Spokespersons 2Health News:South Carolina Youth Named National Epilepsy Spokesperson 2Health News:STERIS Corporation Announces New $300 Million Share Repurchase Authorization 2Health News:STERIS Corporation Announces New $300 Million Share Repurchase Authorization 3Health News:Leukemia Survivor Reaches Landmark Settlement With TransUnion in ID Theft Case 2Health News:Dialysis Corporation of America Earnings Call Reminder 2
... dryer is an electrophoresis gel vacuum dryer that ... dries these gels onto cellophane or filter paper ... elements which heat gels from above. The drying ... V unit includes power cord, porous gel support, ...
... constant voltage power supply, the 105 is very ... range switch control the output, which is variable ... One, two-position switch toggles the bright LED display ... 105 is equipped with an over current detector ...
... simple techniques such as submarine electrophoresis and ... IEF, the Series 90 Programmable Power Supplies ... 90 Programmable Power Supplies are available in ... 6000V., All models operate in constant voltage, ...
MP-250N and 300N is a new style power supply. It is a versatile microprocessor power supply for horizontal or vertical gel electrophoresis. The unit is programmable and offers constant voltage and co...
Medicine Products: