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Patient Receives vProtect(TM) Luminal Shield in First-Ever Vulnerable Plaque Clinical Trial
Date:6/30/2008

ening arteries that are blocked, but we have not succeeded in preventing heart attacks related to plaque rupture. The kind of plaques we are treating in SECRITT do not cause symptoms or seriously affect blood flow, but they are prone to rupture, which can cause a clot, or thrombus. The vProtect(TM) Luminal Shield is designed to prevent that rupture, thereby preventing the thrombus, and the resulting heart attacks." Professor Serruys has been the Director of the Clinical Research Program of the Catheterization Laboratory at the Thoraxcenter, Erasmus University since 1980 and the Head of the Interventional Cardiology Department since 1997. He is a Fellow of the American College of Cardiology and the European Society of Cardiology and a member of the Scientific Council of the International College of Angiology.

Recent studies have shown that most "culprit" lesions in heart attacks, or myocardial infarctions (MI) narrow the vessel lumen by less than 50% prior to the infarct, and only 15% of acute, or sudden, MIs arise from lesions that are more than 60% narrowed on a previous angiogram. Most of these vulnerable plaques would not be eligible for treatment with angioplasty and stenting. "Now is the time to take a new approach, to try and prevent the plaque rupture and prevent the acute event, rather than try to repair the damage after the fact," said Professor Serruys.

The vProtect(TM) Luminal Shield is also undergoing clinical testing for indications where traditional stents are used -- relatively stable, flow-limiting coronary lesions. "The Shield was designed for use in soft lesions. The features that make it well suited for use in vulnerable plaque -- including gentle, self-expanding deployment and ultra-thin struts -- make it useful in other lesions where traditional balloon-expanding stents are currently used," said Patricia Scheller, Chief Executive Officer of Prescient Medical. "There are some uses for which traditional stents do not perform optimall
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SOURCE Prescient Medical
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