Navigation Links
Patient Enrollment Complete in First Trial to Compare Physiologic Guidance vs. Angiographic Guidance of Stent Deployment in Patients with Multivessel Disease
Date:10/22/2007

WASHINGTON, Oct. 22 /PRNewswire/ -- Patient enrollment is complete in the first randomized, prospective, multicenter trial that will compare the clinical outcomes and cost-effectiveness of a physiologic-guided percutaneous coronary intervention (PCI) strategy to an angiographic-guided one in patients with multivessel coronary artery disease (CAD). Bernard De Bruyne, M.D., Ph.D., presented the study update today at the Transcatheter Cardiovascular Therapeutics symposium (TCT 2007) in Washington.

One thousand patients at 20 centers worldwide are participating in the FAME (Fractional flow reserve vs. Angiography for Multivessel Evaluation) study. Participants enrolled in the study meet the following criteria:

-- Coronary lesions in at least two of the three major cardiac vessels

have narrowings of greater than or equal to 50 percent by visual

assessment.

-- The lesions require stenting, according to the investigator.

-- The vessels are large enough to accommodate drug-eluting stents.

After an investigator's visual assessment of an angiogram and notation of which lesions appear to require stenting, patients will be assigned randomly to one of the two PCI strategies. Patients assigned to angiographic guidance will undergo stenting as planned, while patients assigned to physiologic guidance will have fractional flow reserve (FFR) measured in diseased vessels with a coronary pressure wire using a system provided by Radi Medical Systems AB. If FFR is less than or equal to 0.80, meaning the coronary pressure or flow beyond the narrowing is less than or equal to 80% of what it should be, the lesion will be stented.

The study's primary endpoint is a composite of major adverse cardiac events (MACE), including death, myocardial infarction and repeat coronary revascularization at one year. Secondary endpoints include global cost effectiveness after one year, cardiac death and myocardial infarction rate at one year, fu
'/>"/>

SOURCE Radi Medical Systems AB
Copyright©2007 PR Newswire.
All rights reserved

Page: 1 2

Related medicine technology :

1. Monitoring Patient Glucose Levels: New Advances in software make it easier
2. Managing Preanalytical Processes for Patient Safety
3. Hematology Analyzers Simple, Sophisticated Technology Serving All Patients
4. Near-Patient Testing: The Advantages of C-Reactive Protein in Hematological Testing
5. Actemra (tocilizumab) Third Phase III Study Results Show Significant Improvement in Symptoms of Patients with Rheumatoid Arthritis
6. AVI BioPharma Partner Cook Medical Announces Completion of Patient Enrollment for APPRAISAL Phase II Clinical Trial for Treatment of Cardiovascular Disease
7. International ENDORSE Study Shows That the Majority of Hospitalized Patients Surveyed are at Risk for VTE and Many do not Receive Recommended VTE prophylaxis
8. NexMed Announces Completion of Patient Enrollment in Two Pivotal Phase 3 Studies for Anti-Fungal Product
9. Phase III Trial Results Show Superiority of Rivaroxaban over Enoxaparin for the Prevention of Venous Thromboembolism in Patients Undergoing Knee Replacement Surgery
10. New Study Shows That Extending Prophylaxis With Clexane / Lovenox (enoxaparin Sodium Injection) to 5 Weeks is More Effective Than 10 Days for Reducing the Risk of Venous Thromboembolism (VTE) in Acutely ill Medical Patients With Reduced Mobility
11. Phase III Trial Results Show Superiority of Rivaroxaban over Enoxaparin for the Prevention of Venous Thromboembolism in Patients Undergoing Knee Replacement Surgery
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/28/2015)... , Aug. 28, 2015 , ... Dr. Ra from Biostar , Published in ,Stem ... increase of lifespan through multiple IV administration of Adipose-derived ... and life expectancy found , Commercialization within 5 ... determined the possibility that adult mesenchymal stem cells (MSCs) ...
(Date:8/28/2015)... August 28, 2015 The global ... USD 49.12 billion by 2020, growing at a CAGR ... new report by Grand View Research, Inc. Monitoring services ... 49.7% from 2014 to 2020.      (Logo: ... along with rising incidences of chronic diseases such as ...
(Date:8/27/2015)... Biosimilars are not generics and the ... and Drug Administration (FDA) for recognizing that each ... guidance issued today. The FDA,s draft guidance on ... calling for biological products to bear a nonproprietary ... reflects the agency,s thinking that "there is a ...
Breaking Medicine Technology:Korean Researchers Find the Possibility that Adult Mesenchymal Stem Cells (MSCs) May Extend Lifespan 2mHealth Market is Expected to Reach $49.12 Billion By 2020: Grand View Research, Inc. 2mHealth Market is Expected to Reach $49.12 Billion By 2020: Grand View Research, Inc. 3mHealth Market is Expected to Reach $49.12 Billion By 2020: Grand View Research, Inc. 4mHealth Market is Expected to Reach $49.12 Billion By 2020: Grand View Research, Inc. 5Biologics Prescribers Collaborative (BPC) Statement on FDA Draft Guidance entitled "Nonproprietary Naming of Biological Products" 2
... Savient Pharmaceuticals, Inc. (Nasdaq: SVNT ) today ... search for a Chief Executive Officer.  Paul Hamelin, Savient,s ... officer, will continue to lead the day-to-day operations of ... About Savient Pharmaceuticals, Inc. Savient ...
... 2010 LuxteL llc , a quality manufacturer of ... the recent sale of their only remaining manufacturing competitor, ... Ceramic Lighting business. Since April 2001, ... compatible with medical lighting produced by Olympus, Storz, Stryker, Wolf, ...
Cached Medicine Technology:Savient Pharmaceuticals Announces Search for CEO 2LuxteL Brand Is the Longest Standing Recognized Name in the Industry 2
(Date:8/28/2015)... , ... August 28, 2015 , ... On May 30th, ... joined as sponsor of the “Music With A Mission” benefit concert in Mendon, IL. ... event was to raise money to support music education programs in the underfunded local ...
(Date:8/28/2015)... ... August 28, 2015 , ... “ Frequentz ” was featured on ... and coolest applications on the market for iOS, Android, and Windows. Joe Toohey, the ... how this software allows businesses to track product movement from beginning to end. , ...
(Date:8/28/2015)... Omaha, Neb. (PRWEB) , ... August 28, 2015 , ... ... among the 2015 Best Places to Work in Healthcare by Modern Healthcare ... , Now in its eighth year, the Best Places to Work ...
(Date:8/28/2015)... ... ... Dr. Gregory K. Toumayan, D.C., Q.M.E., is now treating patients with back ... hip pain, neck pain, stiffness, muscle spasms, and numbness. , Dr. Toumayan received ... went on to earn his title of Doctor of Chiropractic from the Palmer College ...
(Date:8/28/2015)... ... ... Northridge dentists Dr. Elyson and Dr. Assili are now offering patients ... a one hour treatment of this teeth whitening option. Zoom whitening is ... features that can turn teeth up to nine shades whiter. Effective on a wide ...
Breaking Medicine News(10 mins):Health News:New Video Released on "Music With A Mission" Benefit Concert Headlining Artist Cadillac Three & Best Drug Rehabilitation 2Health News:Track Product Movement from Beginning to End with Frequentz 2Health News:Medical Solutions Recognized as One of 2015 Best Places to Work in Healthcare 2Health News:Medical Solutions Recognized as One of 2015 Best Places to Work in Healthcare 3Health News:Healthpointe Welcomes Dr. Gregory K. Toumayan, Chiropractor, to Colton, Temecula, and Perris 2Health News:Healthpointe Welcomes Dr. Gregory K. Toumayan, Chiropractor, to Colton, Temecula, and Perris 3Health News:Northridge Dentists Dr. Elyson and Dr. Assili Now Offer a Special Promotion on Zoom Teeth Whitening 2
... HealthDay Reporter , TUESDAY, Feb. 15 (HealthDay News) ... common than thought among high school athletes, especially among ... finds. "The risk is that we,re often dealing ... perfect their performance, and sometimes they overdo it," said ...
... The Department of Orthopaedic Surgery at NYU Langone Medical ... centers across the country to participate in the American ... independent, not-for-profit organization created to collect key joint replacement ... device performance and identify underperforming processes while providing information ...
... in reducing risk for acquiring HAIs , Study shows 64 percent ... for both ICU and general medical unit patients ... found a reduced risk of hospital-acquired infections (HAI) when using two ... and water. The study found a 64 percent decrease in the ...
... A new study led by an NYU School of Medicine ... Publication, International Journal of Obesity , challenges the idea ... of teenagers or what parents purchase for their children. Teens ... as adults, however they respond at a lower rate. The ...
... HealthDay Reporter , MONDAY, Feb. 14 (HealthDay News) -- Eating ... dying from heart disease, respiratory disease or any other cause ... report. Fiber has also been tied to a reduced ... the researchers added. In addition, fiber helps bowel movements and ...
... works in the "real world" may more effectively ... only on findings in clinical research settings, according ... Association,s cardiovascular disease prevention guidelines for women., First ... been primarily based on findings observed in clinical ...
Cached Medicine News:Health News:Stress Fractures Hitting High School Athletes 2Health News:Stress Fractures Hitting High School Athletes 3Health News:NYU Langone Department of Orthopaedic Surgery chosen to participate in joint replacement registry 2Health News:NYU Langone Department of Orthopaedic Surgery chosen to participate in joint replacement registry 3Health News:Using chlorhexidine gluconate baths to reduce hospital-acquired infections 2Health News:Calorie labeling has no effect on teenagers' or parents' food purchases 2Health News:Calorie labeling has no effect on teenagers' or parents' food purchases 3Health News:Diet High in Fiber Might Lengthen Your Life 2Health News:Diet High in Fiber Might Lengthen Your Life 3Health News:Updated heart disease prevention guidelines for women focus more on 'real-world' recommendations 2Health News:Updated heart disease prevention guidelines for women focus more on 'real-world' recommendations 3
...
...
EDM Lumbar Drainage Kit with and without Bioglide are fabricated of radiopaque (barium impregnated) silicone tubing, and are packaged with stainless steel stylets inserted in the lumen....
Lumbar External Drainage System (LED) with Touhy needle is indicated for temporary access to the Lumbar Subarachnoid region as a means of draining cerebral spinal fluid (CSF) in order to reduce incre...
Medicine Products: