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Pathfinder Cells Demonstrate Ability to Regenerate Damaged Tissue and Restore Pancreatic Function in a Diabetic Mouse Model
Date:3/29/2011

cardial infarction, and other diseases characterized by organ-specific cell damage. Leveraging its internal discovery of Pathfinder Cells ("PCs") and a proprietary means of isolating these cells from surrounding tissue, Pathfinder is pioneering a new field in regenerative medicine. PCs are a newly identified mammalian cell type present in very low quantities in a variety of organs, including the kidney, liver, pancreas, lymph nodes, myometrium, bone marrow and blood.

Early studies indicate that PCs stimulate regeneration of damaged tissues without the cells themselves being incorporated into the newly generated tissue.  Based on testing to date, the cells appear to be "immune privileged," and their effects appear to be independent of the tissue source of PCs.   In addition to diabetes, positive results have been observed in animal models of cardiac ischemia and renal reperfusion injury.  For more information please visit: www.pathfindercelltherapy.com.  

In December 2010, Pathfinder and SyntheMed, Inc. (OTC Bulletin Board: SYMD) announced that the companies had entered into a definitive merger agreement.  Upon closing, SyntheMed will be renamed  "Pathfinder Cell Therapy, Inc." and the combined company will operate under the leadership of the Pathfinder management team, with the support of a group of regenerative medicine thought leaders on the board of directors.  Closing of the merger is subject to a number of conditions.  For more information please visit: http://www.prnewswire.com/news-releases/pathfinder-llc-and-synthemed-inc-announce-merger-agreement-112334759.html.

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