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Pangu BioPharma, aTyr Pharma's Subsidiary in Hong Kong, Receives New Research Grant From Hong Kong Innovation and Technology Commission
Date:3/1/2010

SAN DIEGO, March 1 /PRNewswire/ -- The Innovation and Technology Commission of the Hong Kong government has awarded Pangu BioPharma, the Hong Kong subsidiary of aTyr Pharma, a second grant to fund research it is performing in collaboration with the Hong Kong University of Science and Technology (HKUST).  The Innovation and Technology Fund (ITF) provides matching funds over the next 18 months to expand Pangu's successful work in the identification and characterization of naturally occurring splice variants of human tRNA synthetases.  Research at Pangu BioPharma and aTyr Pharma showed that these naturally occurring splice variants result in resected proteins ("resectins") that have functions distinct from the normal protein synthesis activities associated with tRNA synthetases.  These resectins perform a variety of extracellular signaling functions essential for normal human biology, and have the potential to be used as biotherapeutics in a variety of disease settings, including immunological, hematopoietic, neurological disorders, and inflammatory conditions.  The research at Pangu BioPharma is focused on identifying and characterizing new examples of the tRNA synthetases resectins arising from alternative splicing events, as well as on identifying their biological activities and potential applications as novel biotherapeutics.  The previous 18 month ITF award to Pangu BioPharma led to the building of a strong proprie
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