Navigation Links
Pangu BioPharma, aTyr Pharma's Subsidiary in Hong Kong, Receives New Research Grant From Hong Kong Innovation and Technology Commission
Date:3/1/2010

SAN DIEGO, March 1 /PRNewswire/ -- The Innovation and Technology Commission of the Hong Kong government has awarded Pangu BioPharma, the Hong Kong subsidiary of aTyr Pharma, a second grant to fund research it is performing in collaboration with the Hong Kong University of Science and Technology (HKUST).  The Innovation and Technology Fund (ITF) provides matching funds over the next 18 months to expand Pangu's successful work in the identification and characterization of naturally occurring splice variants of human tRNA synthetases.  Research at Pangu BioPharma and aTyr Pharma showed that these naturally occurring splice variants result in resected proteins ("resectins") that have functions distinct from the normal protein synthesis activities associated with tRNA synthetases.  These resectins perform a variety of extracellular signaling functions essential for normal human biology, and have the potential to be used as biotherapeutics in a variety of disease settings, including immunological, hematopoietic, neurological disorders, and inflammatory conditions.  The research at Pangu BioPharma is focused on identifying and characterizing new examples of the tRNA synthetases resectins arising from alternative splicing events, as well as on identifying their biological activities and potential applications as novel biotherapeutics.  The previous 18 month ITF award to Pangu BioPharma led to the building of a strong proprietary portfolio of novel compositions for the treatment of the aforementioned diseases.  

Pangu BioPharma is the result of an innovative partnership between aTyr Pharma and the Hong Kong University of Science and Technology (HKUST).  Dr. James Cai, President of Pangu BioPharma, notes that "Support from Hong Kong's government and universities are important elements to attract exciting drug discovery and development companies to make Hong Kong a leader in the biotechnology industry. Funding from Hong Kong's Innovation and Technology Commission to support efforts such as ours is proof that Hong Kong is committed to building a strong biotechnology center in China."

A visiting scholar at the Institute of Advanced Science at HKUST, Professor Paul Schimmel of The Scripps Research Institute and co-founder of aTyr Pharma as well as Pangu BioPharma, was the driver in building the partnership between aTyr Pharma and HKUST.  A world renowned expert on tRNA synthetases, Paul Schimmel has also been the co-founder or founding director of numerous successful biotechnology companies, including Sirtris Pharmaceuticals, Alnylam, Repligen Corporation, Alkermes, Inc., Momenta Pharmaceuticals and Cubist Pharmaceuticals, which were taken public on the NASDAQ and are well established as companies that develop and market new medicines.  "This is an exciting time to have a biotechnology endeavor in Hong Kong.  The government and university system in Hong Kong have a powerful vision to translate research into a thriving biotechnology industry that connects to China and the rest of Asia.  aTyr Pharma and Pangu BioPharma are at the forefront of this effort and are pleased to have the ITC and HKUST as partners.  We particularly value the contributions of Professors Mingjie Zhang and Nancy Ip of the Biochemistry Department at HKUST, Angelina Yee of the IAS, and Matthew Yuen of HKUST's Research and Development group," says Professor Schimmel.  

According to Jeff Watkins, CEO of aTyr Pharma, "Pangu BioPharma is the model for a successful collaboration of government, university and industry partnership.  With the support of HKUST and funding from the ITC, we have attracted a highly skilled group of scientists and established a well equipped lab at HKUST using the latest techniques, such as next generation sequencing. The intellectual property being generated by Pangu BioPharma continues to reinforce our preeminence in the field of resectin biology and their therapeutic applications."

SOURCE aTyr Pharma

Back to top
'/>"/>
SOURCE aTyr Pharma
Copyright©2010 PR Newswire.
All rights reserved

Related medicine technology :

1. Pangu BioPharma, aTyr Pharmas Subsidiary in Hong Kong, Files Three Patent Applications
2. CB1400, Patented by Canopus BioPharma, Enters Phase II Clinical Trials for the Prevention of Mucositis in Patients With Cancer of the Head and Neck
3. DOR BioPharma, Inc. Executes $400,000 Equity Investment Agreement With Numoda Corporation
4. Berger & Montague, P.C., Files Class Action Against Hemispherx Biopharma, Inc. Extending the End of the Class Period to December 1, 2009, When the Company Announced That the FDA Found No Evidence of Efficacy of Its Drug
5. Clinical Trial Effectiveness: How Pharmas & Biotechs Save Cost with Savvy Investigator Management
6. Pharmasset Presents R7128 Phase 1 Single Ascending Dose Study in Healthy Volunteers
7. Pharmasset Commences Dosing in Phase 3 Registration Studies of Clevudine for HBV
8. Pharmasset Commences Dosing in 28-Day Combination Study of R7128 with Pegasys(R) plus Copegus(R) for Hepatitis C
9. Pharmasset Announces Clevudine and R7128 Presentations at HEP-DART
10. Pharmasset Announces R7128 Achieves 85% Rapid Virologic Response in a 4-week Combination Study for the Treatment of Chronic Hepatitis C
11. Roche and Pharmasset To Present the R7128 Monotherapy Resistance Profile
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/23/2016)... Bracket , a leading clinical trial technology ... outcomes platform, Bracket eCOA (SM) 6.0, at the 52 ... 30, 2016 in Philadelphia , Pennsylvania.  A ... product of its kind to fully integrate with RTSM, will ... 6.0 is a flexible platform for electronic clinical outcomes assessments ...
(Date:6/23/2016)... Colombia , June 23, 2016  Astellas today announced the establishment of Astellas Farma Colombia (AFC), a new ... affiliate in Latin America . ... ... ... ...
(Date:6/23/2016)... June 23, 2016 The vast majority of ... dialysis facility.  Treatments are usually 3 times a week, ... visit, including travel time, equipment preparation and wait time. ... especially grueling for patients who are elderly and frail.  ... nursing and rehabilitation centers for some duration of time. ...
Breaking Medicine Technology:
(Date:6/26/2016)... ... 26, 2016 , ... Brent Kasmer, a legally blind and certified personal trainer is helping to ... app. The fitness app plans to fix the two major problems leading the fitness industry ... fits all type program , They don’t eliminate all the reasons people quit ...
(Date:6/25/2016)... , ... June 25, 2016 , ... Austin residents seeking ... American College of Mohs Surgery and to Dr. Russell Peckham for medical and surgical ... effective treatment for skin cancer. The selective fellowship in Mohs Micrographic Surgery completed by ...
(Date:6/25/2016)... , ... June 25, 2016 , ... First Choice ... States, named Dr. Sesan Ogunleye, as the Medical Director of its new Mesquite-Samuell Farm ... Medical Director of our new Mesquite location,” said Dr. James M. Muzzarelli, Executive Medical ...
(Date:6/25/2016)... ... 25, 2016 , ... On Friday, June 10, Van Mitchell, Secretary of the ... to iHire in recognition of their exemplary accomplishments in worksite health promotion. , The ... Health & Wellness Symposium at the BWI Marriott in Linthicum Heights. iHire was one ...
(Date:6/24/2016)... Michigan (PRWEB) , ... June 24, 2016 , ... Those ... deal with these feelings, many turn to unhealthy avenues, such as drug or alcohol ... of Marne, Michigan, has released tools for healthy coping following a traumatic event. , ...
Breaking Medicine News(10 mins):