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PTC Therapeutics and Parent Project Muscular Dystrophy Advance Drug Discovery Program to Improve Heart Function in Duchenne/Becker Muscular Dystrophy Patients
Date:2/1/2011

ein.  The new PPMD grant will support medicinal chemistry efforts to improve the chemical, biological and pharmaceutical properties of these early molecules with the goal of identifying a development candidate for clinical studies.

"We are pleased to continue and expand our collaboration with PPMD in our ongoing effort to bring new treatments to Duchenne and Becker muscular dystrophy patients," stated Stuart W. Peltz, Ph.D., President & CEO of PTC Therapeutics.  "Our commitment to DBMD patients started more than a decade ago when we initiated our nonsense suppression program.  Those efforts led to ataluren, which has the potential to be the first therapy to treat the underlying cause of nonsense mutation DBMD.  Our experience developing ataluren will be beneficial to SERCA2a and our other neuromuscular programs as we move forward in development.  Our goal is to develop safe and effective treatments for all patients with DBMD."

About Parent Project Muscular Dystrophy

Parent Project Muscular Dystrophy (PPMD) is a national not-for-profit organization founded in 1994 by parents of children with Duchenne and Becker muscular dystrophy. The organization's mission is to improve the treatment, quality of life and long-term outlook for all individuals affected by Duchenne muscular dystrophy through research, advocacy, education and compassion. PPMD is headquartered in Middletown, Ohio with offices in Hackensack, New Jersey. For more information, visit www.parentprojectmd.org.

About PTC Therapeutics, Inc.

PTC is a biopharmaceutical company focused on the discovery, development and commercialization of orally administered small-molecule drugs that target post-transcriptional control processes. Post-transcriptional control processes regulate the rate and timing of protein production and are of central importance to proper cellular function. PTC's internally
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SOURCE PTC Therapeutics, Inc.
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