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PROMUS Element™ Stent Demonstrates Exceptional Safety and Effectiveness in PLATINUM Small Vessel Study
Date:5/20/2011

NATICK, Mass. and PARIS, May 20, 2011 /PRNewswire/ -- Boston Scientific Corporation (NYSE: BSX) today announced 12-month results from its PLATINUM Small Vessel study, demonstrating excellent safety and effectiveness outcomes for the 2.25 mm PROMUS Element™ Everolimus-Eluting Platinum Chromium Stent System in treating small vessel coronary disease.  The study is a global, prospective, single-arm, subtrial of the PLATINUM clinical program.  It compares the PROMUS Element Stent (2.25 mm) in 94 patients with small vessels (greater than or equal to 2.25 to less than 2.50 mm reference vessel diameter and less than or equal to 28 mm lesion length) to a pre-specified performance goal based on results from patients treated with the TAXUS® Express® Paclitaxel-Eluting Stent.

Analysis of the data was presented at the annual EuroPCR Scientific Program in Paris by Ian T. Meredith, M.B.B.S., Ph.D., Professor of Cardiology and Medicine, Monash University, and Executive Director of Monash Cardiovascular Research Center, Monash Medical Centre, Clayton, Victoria, Australia, and Co-Principal Investigator for the PLATINUM clinical program.

"The PLATINUM Small Vessel data demonstrate exceptionally low rates of revascularization, while reporting no myocardial infarction or stent thrombosis at one year in patients treated with the 2.25 mm PROMUS Element Stent," said Professor Meredith.  "These results are impressive, especially considering the small vessel diameter in this patient population."

The PLATINUM Small Vessel study met its primary endpoint of target lesion failure (TLF) at 12 months with a rate of 2.4 percent for the 2.25 mm PROMUS Element Stent in the per protocol population compared to a pre-specified performance goal of 21.1 percent (p<0.001) based on historical outcomes for the 2.25 mm TAXUS Express Stent.  Components of TLF in the p
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SOURCE Boston Scientific Corporation
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2. Boston Scientific Begins Clinical Trial Enrollment in China for PROMUS Element™ Everolimus-Eluting Stent
3. Boston Scientific Announces Clinical Data Supporting Safety and Efficacy of Platinum Chromium PROMUS Element™ Stent
4. Boston Scientific Announces Japanese Approval for PROMUS(R) Everolimus-Eluting Coronary Stent System
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