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PNH Patients With Lower Levels of Hemolysis, Mild Anemia and Minimal Transfusion Support Have Significant Disease Burden; Soliris(R) Therapy Provided Clinical Improvements in PNH Patients Regardless of Disease Severity
Date:12/11/2007

(4) Parker C, Omine M, Richards S, et al. Diagnosis and management of

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and distribution-based methods to derive minimal clinically important

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paroxysmal nocturnal hemoglobinuria (PNH) and survival of patients in

Yorkshire [abstract]. Blood. 2006;108(11):985.

(7) Socie G, Mary J Yves, de Gramont A, et al. Paroxysmal nocturnal

haemoglobinuria: long-term follow-up and prognostic factors. Lancet

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(8) Johnson RJ, Hillmen P. Paroxysmal nocturnal hemoglobinemia: Nature's

gene therapy? J Clin Path: Mol Pathol. 2002;55:145-152.

(9) Wang, et al. Clinical significance of a minor population of

paroxysmal nocturnal hemoglobinuria-type cells in bone marrow failure

syndrome. Blood 2002;100:3897-3902.

(10) Iwanga, et al. Paroxysmal nocturnal haemoglobinuria clones in

patients with myelodysplastic syndromes. Brit J Haem. 1998; 102:465-

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(12) Hill A, Richards S, Hillmen P. Recent developments in the

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British Journal of Haematology 2007; 137:3, 181-192.


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SOURCE Alexion Pharmaceuticals, Inc.
Copyright©2007 PR Newswire.
All rights reserved

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