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PNH Patients Treated with Soliris(TM) Experienced Dramatic Reduction in Blood Clots During Clinical Trials
Date:8/20/2007

at all, the risk that Soliris will not generate interest among physicians, the risk that estimates regarding the number of PNH patients are inaccurate, the risk that pending litigation may be resolved adversely, and a variety of other risks set forth from time to time in Alexion's filings with the Securities and Exchange Commission, including but not limited to the risks discussed in Alexion's Quarterly Report on Form 10-Q for the period ended June 30, 2007 and in our other filings with the Securities and Exchange Commission. Alexion does not intend to update any of these forward-looking statements to reflect events or circumstances after the date hereof, except when a duty arises under law.

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intravascular hemolysis and extracellular plasma hemoglobin. JAMA

2005; 293:1653-1662.

(2) Parker C, Omine M, Richards S, et al. Diagnosis and management of

paroxysmal nocturnal hemoglobinuria. Blood 2005; 106:3699-3709.

(3) Socie G, Mary J Yves, de Gramont A, et al. Paroxysmal nocturnal

haemoglobinuria: long-term follow-up and prognostic factors. Lancet

1996; 348:573-577.

(4) Hillmen P. Lewis SM, Bessler M, Luzzatto L, Dacie JV. Natural history

of paroxysmal nocturnal hemoglobinuria. N Engl J Med 1995;

333:1253-1258.

(5) Moyo VM, Mukhina GL, Garrett ES, Brodsky RA. Natural history of

paroxysmal nocturnal haemoglobinuria using modern diagnostic assays.

Br J Haematol. 2004;126:133-138.

(6) Araten DJ, Thaler HT, Luzzatto L. High incidence of thrombosis in

African-American and Latin-American patients with Paroxysmal

Nocturnal Haemoglobinuria. Thromb Haemost. 2005;93:88-91.

(7) Nishimura J, Kanakura Y, Ware RE et al. Clinical course and flow

cytometric analysis of paroxysmal nocturnal hemoglobinuria in the

United States and J
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SOURCE Alexion Pharmaceuticals, Inc.

Copyright©2007 PR Newswire.

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