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PEAK Surgical Announces Positive Results From Preclinical Study of PEAK PlasmaBlade(TM) for Obstetric and Gynecologic Surgery
Date:5/6/2008

study, freshly excised human abdominal tissue was cut using the PEAK PlasmaBlade, an uncoated traditional electrosurgery scalpel, a teflon-coated traditional electrosurgery scalpel and a fine wire and ceramic electrosurgery scalpel. Histology samples were immediately harvested to evaluate acute thermal tissue injury.

Also as part of the study, full-thickness skin incisions were made on porcine skin using a traditional electrosurgery device, the PEAK PlasmaBlade and a standard scalpel blade. Incisions were made at days 0, 21, 28, 35 and 42, and bleeding was evaluated for 60 seconds post-incision. The wounds were then sutured to allow for healing, and digital photos of the wounds were taken every seven days to evaluate scarring based on a visual analog scale. Histological examination was conducted to evaluate healing and inflammatory response.

Study Results

Histological evaluation of the ex vivo human skin showed that the PEAK PlasmaBlade cuts produced minimal collateral damage compared to cuts made with the other electrosurgery instruments.

In the porcine skin cuts, bleeding for 60 seconds following incision was reduced by 60 percent in the wounds made by the PEAK PlasmaBlade compared with those made by the standard scalpel (p=0.0001). Wound sections showed a 75 percent reduction in acute thermal damage with the PEAK PlasmaBlade compared with the traditional electrosurgery scalpel (p<0.03). After six weeks, there was no significant difference in scar formation between the PEAK PlasmaBlade and the standard scalpel; however, scarring was reduced by 66 percent with the PEAK PlasmaBlade compared with the traditional electrosurgery device (p<0.04). Staining for inflammatory cells showed significantly less infiltration in the wounds made by the standard scalpel and the PEAK PlasmaBlade, indicating less inflammation, compared with wounds made by the traditional electrosurgery device.

"Because of its ability to precisely cut tissue while c
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SOURCE PEAK Surgical, Inc.
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