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OxThera startar klinisk studie inom Primär Hyperoxaluri
Date:1/8/2014

STOCKHOLM, January 8, 2014 /PRNewswire/ --

OxThera AB, ett Stockholmsbaserat privat biofarmaceutiskt bolag, meddelar idag att det har startat en klinisk studie inom Primär Hyperoxaluri.  Offentliggörandet stärker ytterligare företagets position som ledare i att utveckla terapier för behandling av hyperoxaluri, en svår sjukdom som leder till njurskador och njurkollaps, om den inte behandlas.

"Vi är mycket glada att meddela att vi har startat vår konfirmerande kliniska studie inom Primär Hyperoxaluri", säger Elisabeth Lindner, VD för OxThera. "Vi är övertygade om att vår nya Oxabact® -produkt har potential att hjälpa patienter med denna svåra sjukdom", fortsätter Elisabeth Lindner.

Den placebokontrollerade studien, OC5-DB-01, utförs på 7 kliniker i tre länder och kommer att inkludera totalt 24 patienter. Resultatet väntas efter sommaren. Oxabact® är en oral produkt som utgörs av högkoncentrerade frystorkade levande bakterier (Oxalobacter formigenes), som administreras i kapslar. Kapslarna är designade för att leverera produkten i tunntarmen, där den så kallade enteriska elimineringen av oxalat initieras. En komplett utvecklingsplan för behandling av patienter som lider av Primär Hyperoxaluri med Oxabact®, har implementerats.

Primär Hyperoxaluri (PH) är en sällsynt autosomal recessiv sjukdom som leder till markant höjda nivåer av endogent oxalat i plasma och urin. Höga nivåer av oxalat ger njurskador och förkalkning av njurarna. Om sjukdomen inte behandlas, kan den orsaka njurkollaps och prematur död. Det finns idag ett stort behov av en fungerande medicinsk behandling för PH. I nuläget är d
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SOURCE OxThera AB
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