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Otonomy Announces Preclinical Results Supporting Intra-operative Use of OTO-201 for Common Childhood Procedure
Date:6/8/2011

ren experience otitis media by the time they reach three years of age.  Oral antibiotics are considered standard of care for patients with otitis media due to infection. Patients with recurrent or persistent otitis media are routinely referred to ENT surgeons for placement of a tympanostomy tube in one or both ears. Industry sources estimate that approximately one million patients undergo tympanostomy tube placement surgery each year in the U.S.

About OtonomyOtonomy is a clinical stage biopharmaceutical company developing innovative therapeutics for diseases and disorders of the inner and middle ear.  There are currently no FDA-approved drug treatments for the nearly 30 million Americans that are affected by debilitating hearing and balance diseases and disorders such as Meniere's disease, sudden sensorineural hearing loss, noise-induced hearing loss, age-related hearing impairment and tinnitus.  Otonomy's core technology is a sustained release formulation developed for optimal delivery of drugs to the middle and inner ear with a single intratympanic (IT) injection.  This technology has broad applicability across a range of therapeutic classes and two products based on this platform are in active development.

Otonomy's lead product candidate, OTO-104, is a sustained release formulation of the steroid dexamethasone.  A Phase 1b clinical trial in Ménière's disease patients has recently been completed, and future studies are being planned in Meniere's disease and other inner ear disorders.  OTO-201, the company's second product candidate, is a novel sustained release antibiotic being developed for the treatment of chronic otitis media.  OTO-201 clinical trials are expected to begin in 2011.  Additional product candidates are expected to target acute and chronic forms of hearing loss, balance disorders, and tinnitus.

For more information visit: www.otonomy.com'/>"/>

SOURCE Otonomy, Inc.
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