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Otonomy Acquires Assets and Patent Rights for Tinnitus Program
Date:10/31/2013

lifies our commitment to broadly address unmet medical need in the treatment of otic disorders."

"We are pleased to transfer the data and results from our efforts, and IP surrounding gacyclidine to further the development of OTO-311. We believe that prolonged drug exposure to the inner ear is essential for optimal treatment and that Otonomy's technology featuring single injection delivery is a patient friendly innovation," stated Alfred Mann. "OTO-311 has exciting potential to provide relief to the millions of individuals worldwide who suffer from tinnitus."

About Tinnitus

Tinnitus is the medical term for hearing noises in the ears when there is no outside source of the sounds. It is often described as a ringing in the ears but can also sound like roaring, clicking, hissing or buzzing, and can be soft or loud. An estimated one in five adults may experience tinnitus in one or both ears. While the most common cause of tinnitus is exposure to loud noise, a number of other factors can be involved including heart or blood vessel problems, hormonal changes in women, ear and sinus infections, certain medications and thyroid problems. People with severe tinnitus may have trouble hearing, working or even sleeping. At this time, there is no cure for tinnitus and there are no FDA-approved drugs for treating this debilitating condition.

About Otonomy

Otonomy is a clinical stage biopharmaceutical company developing innovative therapeutics for diseases and disorders of the ear. Otonomy's proprietary technology provides sustained exposure of drugs to the middle and inner ear following a single intratympanic (IT) injection. Otonomy has three product candidates in development. OTO-104 is a steroid that has completed a Phase 1b clinical trial in Meniere's disease patients. OTO-201 is an antibiotic that has recently completed a Phase 1b clinical trial in pediatric patients with middle ear effusion at the time of tympanost
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