Navigation Links
Orion Genomics Gains Exclusive Worldwide Rights to the IGF2 Gene for Colorectal Cancer Risk Testing Through Licensing Agreement With Johns Hopkins University
Date:6/11/2008

ST. LOUIS, June 11 /PRNewswire/ -- Orion Genomics announced today that the company entered into a worldwide exclusive license agreement with The Johns Hopkins University (JHU) to commercialize products that identify patients at risk for colorectal cancer. The license is based on a suite of issued and pending JHU patents covering imprinting abnormalities of the insulin-like growth factor 2 gene (IGF2). Orion's simple blood-based risk assessment test is being designed to identify people who carry the IGF2 biomarker and may be at increased risk of developing sporadic colorectal cancer. It is expected that the test will enable at-risk patients to undergo screening for colorectal cancer significantly earlier, allowing physicians to remove precancerous polyps and prevent future colon cancer.

Two published studies involving more than 200 patients have found that colorectal cancer and adenoma patients are at least five times more likely to carry the IGF2 biomarker than age-matched cancer-free patients serving as controls.

"We are pleased to obtain this exclusive license from The Johns Hopkins University to complete the development of our lead cancer risk assessment product and enter the market in the near future," said Nathan D. Lakey, President and CEO of Orion Genomics. "Our colorectal cancer risk test has the potential to save lives by identifying a group of high risk individuals who are likely to develop colorectal cancer at a younger age, and who should undergo colonoscopy screening 10 to 20 years earlier than the age that is currently recommended."

Loss of imprinting of IGF2 is a non-heritable epigenetic mutation detected in the blood of seven to 10 percent of the general population. Although epigenetic mutations do not affect the DNA sequence of a gene, cancer associated epigenetic changes can either turn off or "silence" genes that normally suppress cancer, or can inappropriately turn on genes that can lead to malignant cellular activity.
'/>"/>

SOURCE Orion Genomics
Copyright©2008 PR Newswire.
All rights reserved

Page: 1 2

Related medicine technology :

1. Orion Genomics Announces the Discovery of Novel Breast Cancer Biomarkers
2. Rosetta Genomics and M. D. Anderson to Develop a MicroRNA-based Diagnostic Test to Identify Risk of Recurrence of Lung Cancer
3. Rosetta Genomics to Present Multiple Posters at the 44th Annual Meeting of the American Society of Clinical Oncology (ASCO)
4. Rosetta Genomics Signs Agreement With West Coast CLIA Certified Lab to Develop and Validate Tests Applying Companys MicroRNA Technology
5. Columbia University Medical Center and Rosetta Genomics Announce Columbia Universitys Submission of the First Cancer Diagnostic Test Based on Rosetta Genomics Proprietary MicroRNA Technology for Approval to the New York State Department of Health Clinica
6. Virogenomics, Inc. Awarded $2 Million National Institute of Standards and Technology (NIST) Advanced Technology Program Grant to Develop Integrated Diagnostic Biosensors
7. Harvard Medical School-Partners HealthCare Center for Genetics and Genomics Successfully Completes Evaluation of AutoGenomics 2C9-VKORC1 Panel to Assess Warfarin Sensitivity
8. Harvard Medical School-Partners HealthCare Center for Genetics and Genomics Successfully Completes Evaluation of AutoGenomics 2C9-VKORC1 Panel to Assess Warfarin Sensitivity
9. Grocery Manufacturers Association: Study Signals Progress in Battle Against Obesity
10. Annual Conference on Vaccine Research to Highlight Not Only Health Benefits But Also Economic Gains
11. Lixte Biotechnology Holdings Announces That Anti-Cancer Activity Against Glioblastoma in an Animal Model Was Reported at the Annual Meeting of the American Association of Cancer Research
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/11/2014)... According to a new ... Material, Application (Healthcare, Homeland security, Industrial application, Nuclear ... Hand-Held Instruments, Fixed, and Installed Instruments) & Geography ... by MarketsandMarkets, the Scintillator Market is expected to ... to 2020, and reach $479.16 Million in 2020. ...
(Date:7/11/2014)... 2014 According to a new ... Market (Endoscopes, Endoscopic Operative Devices, and Visualization Systems) - ... 2013-2019" the global endoscopy devices market was valued at ... grow at a CAGR of 6.8% from 2013 to ... billion in 2019. Browse the full Endoscopy ...
(Date:7/10/2014)... MUMBAI, India , July 11, 2014 /PRNewswire/ ... the treatment of cancer are being highlighted in ... Mumbai from 10-12 July, 2014.  Renowned ... meeting to share best practices and exchange knowledge ... more precise, accurate and efficient. ...
Breaking Medicine Technology:Scintillator Market will be worth $479.16 Million by 2020 2Scintillator Market will be worth $479.16 Million by 2020 3Scintillator Market will be worth $479.16 Million by 2020 4Global Endoscopy Devices Market is Expected to Reach USD 36.9 Billion by 2019: Transparency Market Research 2Global Endoscopy Devices Market is Expected to Reach USD 36.9 Billion by 2019: Transparency Market Research 3Global Endoscopy Devices Market is Expected to Reach USD 36.9 Billion by 2019: Transparency Market Research 4Global Endoscopy Devices Market is Expected to Reach USD 36.9 Billion by 2019: Transparency Market Research 5Global Endoscopy Devices Market is Expected to Reach USD 36.9 Billion by 2019: Transparency Market Research 6Improving quality and access to advanced cancer care in India and South Asia 2Improving quality and access to advanced cancer care in India and South Asia 3Improving quality and access to advanced cancer care in India and South Asia 4Improving quality and access to advanced cancer care in India and South Asia 5
... , NEW BRUNSWICK, N.J., Dec. 17 ... has opened the 2010 call for nominations. The $100,000 ... contributions towards the improvement of human health. Nomination ... be accepted until February 15, 2010. The Award winner ...
... LITTLE FALLS, N.J., Dec. 17 CANTEL MEDICAL CORP. ... Directors intends to pay, for the first time, a semiannual cash ... on the Company,s common stock. The Board declared the first cash ... paid on January 29, 2010 to shareholders of record at the ...
Cached Medicine Technology:Nominations Open for the 2010 Dr. Paul Janssen Award for Biomedical Research 2Nominations Open for the 2010 Dr. Paul Janssen Award for Biomedical Research 3Nominations Open for the 2010 Dr. Paul Janssen Award for Biomedical Research 4Cantel Medical Authorizes Semiannual Dividend 2
(Date:7/13/2014)... 13, 2014 Recently, 2014QuinceaneraDresses.com, the ... unveiled its new range of gorgeous Quinceanera ... the demand for elegant Quinceanera outfits is huge. ... items. All the company’s newly released dresses are ... are all elegant and vivid. , It ...
(Date:7/13/2014)... Recently, MyDressCity.com, one of the most popular suppliers of ... its new range of elegant Quinceanera dresses . ... discounted prices. Worldwide clients can enjoy this special offer ... online shop, there are plenty of beautiful dresses for ... materials. MyDressCity.com’s hot items are prom gowns, bridesmaid gowns, ...
(Date:7/13/2014)... 13, 2014 Epidemiologists forecast an increase ... 6MM, from 8,062 diagnosed incident cases in 2013 to ... Growth Rate (AGR) of 4.35%, during the forecast period. ... of diagnosed incident cases of aGVHD in the 6MM, ... the lowest number of diagnosed incident cases of aGVHD, ...
(Date:7/13/2014)... ability to identify odors might indicate the development ... of the eye could indicate the build-up of ... brain, according to the results of four research ... Conference 2014 (AAIC 2014) in Copenhagen. , In ... identify odors was significantly associated with loss of ...
(Date:7/13/2014)... Wright & Schulte LLC has learned that the ... of 2015, in U.S. District Court, District of South ... process in the South Carolina federal court where ... multidistrict litigation (MDL). The complaints pending in the Louisiana ... that they took the statin medication to lower their ...
Breaking Medicine News(10 mins):Health News:2014QuinceaneraDresses.com Releases Its New Quinceanera Dresses 2Health News:Cheap Elegant Quinceanera Dresses Unveiled by MyDressCity.com 2Health News:Graft-Versus-Host Disease Market (GVHD) Growing at 4.35% AGR to 2023 Says a New Report Available at ReportsnReports.com 2Health News:Graft-Versus-Host Disease Market (GVHD) Growing at 4.35% AGR to 2023 Says a New Report Available at ReportsnReports.com 3Health News:Graft-Versus-Host Disease Market (GVHD) Growing at 4.35% AGR to 2023 Says a New Report Available at ReportsnReports.com 4Health News:Smell and eye tests show potential to detect Alzheimer's early 2Health News:Smell and eye tests show potential to detect Alzheimer's early 3Health News:Smell and eye tests show potential to detect Alzheimer's early 4Health News:Smell and eye tests show potential to detect Alzheimer's early 5Health News:Smell and eye tests show potential to detect Alzheimer's early 6Health News:Smell and eye tests show potential to detect Alzheimer's early 7Health News:Lipitor Lawsuits Move Forward With Scheduling Of First Bellwether Trial 2Health News:Lipitor Lawsuits Move Forward With Scheduling Of First Bellwether Trial 3Health News:Lipitor Lawsuits Move Forward With Scheduling Of First Bellwether Trial 4
... Antares, parent company, Medical Mutual of Ohio to ... processes, reduced costs, improved ... Software, developer of the,OnBase document and process management ... Management Solutions as the new provider of,enterprise document ...
... LISTERINE(R) Products Launch New Children,s Fluoride Rinse, with Special Tinting ... ... MORRIS PLAINS, N.J., March 11 Parents confess that kids,can ... care.,According to a recent survey of parents with children ages six ...
... of EUSA,s Transatlantic ... Commercialization Platform ... EUSA Raises Over US$50 Million to Fund Acquisition and Other ... Pharma Inc (,EUSA,), a transatlantic specialty pharmaceutical company,focused on oncology, ...
... LifeMasters Supported,SelfCare, Inc., a national leading ... announced it has received $15 million in ... one of its,earliest investors, Saints Capital, and ... financial flexibility to continue to execute on,its ...
... Will Address Attorney Weight Loss Coaching and Present Ideas On How ... ... Leventhal Weight Loss,Incorporated, the first in the nation executive weight ... that its president and founder Mark Leventhal, Esq. will address,the Washington, ...
... Made to Deny Union for Healthcare Employees in Ohio, ... (CNA) has launched an anti-union campaign against nurses,and other ... by the workers to unite in District 1199 of ... votes -- this Wednesday and Friday at nine Catholic,Healthcare ...
Cached Medicine News:Health News:Antares Management Solutions Selects Hyland Software's OnBase 2Health News:The Disappearing Toothbrush: Survey Reveals Kids' Top Excuses to Avoid Brushing 2Health News:The Disappearing Toothbrush: Survey Reveals Kids' Top Excuses to Avoid Brushing 3Health News:The Disappearing Toothbrush: Survey Reveals Kids' Top Excuses to Avoid Brushing 4Health News:EUSA Pharma to Acquire US Specialty Oncology Company Cytogen 2Health News:EUSA Pharma to Acquire US Specialty Oncology Company Cytogen 3Health News:EUSA Pharma to Acquire US Specialty Oncology Company Cytogen 4Health News:EUSA Pharma to Acquire US Specialty Oncology Company Cytogen 5Health News:LifeMasters Strengthens Capital Structure with $15 Million in Funding from Existing Investors 2Health News:LifeMasters Strengthens Capital Structure with $15 Million in Funding from Existing Investors 3Health News:Mark Leventhal To Address Nixon Peabody LLP 2Health News:SEIU: 'Union-Busting' by California Nurses Association 2
3 mm, 130 degree upwards cutting, detachable....
Sabre 180 is a powerful niche generator....
The Sabre 2400 provides high power performance and key user features to meet today's demanding electrosurgical needs. It is an ideal general-purpose electrosurgical generator....
The ExcaliburPlus PC is the most powerful isolated ESU with 10,000 V PTP in spray coag....
Medicine Products: