Navigation Links
Orion Genomics Gains Exclusive Worldwide Rights to the IGF2 Gene for Colorectal Cancer Risk Testing Through Licensing Agreement With Johns Hopkins University
Date:6/11/2008

ST. LOUIS, June 11 /PRNewswire/ -- Orion Genomics announced today that the company entered into a worldwide exclusive license agreement with The Johns Hopkins University (JHU) to commercialize products that identify patients at risk for colorectal cancer. The license is based on a suite of issued and pending JHU patents covering imprinting abnormalities of the insulin-like growth factor 2 gene (IGF2). Orion's simple blood-based risk assessment test is being designed to identify people who carry the IGF2 biomarker and may be at increased risk of developing sporadic colorectal cancer. It is expected that the test will enable at-risk patients to undergo screening for colorectal cancer significantly earlier, allowing physicians to remove precancerous polyps and prevent future colon cancer.

Two published studies involving more than 200 patients have found that colorectal cancer and adenoma patients are at least five times more likely to carry the IGF2 biomarker than age-matched cancer-free patients serving as controls.

"We are pleased to obtain this exclusive license from The Johns Hopkins University to complete the development of our lead cancer risk assessment product and enter the market in the near future," said Nathan D. Lakey, President and CEO of Orion Genomics. "Our colorectal cancer risk test has the potential to save lives by identifying a group of high risk individuals who are likely to develop colorectal cancer at a younger age, and who should undergo colonoscopy screening 10 to 20 years earlier than the age that is currently recommended."

Loss of imprinting of IGF2 is a non-heritable epigenetic mutation detected in the blood of seven to 10 percent of the general population. Although epigenetic mutations do not affect the DNA sequence of a gene, cancer associated epigenetic changes can either turn off or "silence" genes that normally suppress cancer, or can inappropriately turn on genes that can lead to malignant cellular activity.
'/>"/>

SOURCE Orion Genomics
Copyright©2008 PR Newswire.
All rights reserved

Page: 1 2

Related medicine technology :

1. Orion Genomics Announces the Discovery of Novel Breast Cancer Biomarkers
2. Rosetta Genomics and M. D. Anderson to Develop a MicroRNA-based Diagnostic Test to Identify Risk of Recurrence of Lung Cancer
3. Rosetta Genomics to Present Multiple Posters at the 44th Annual Meeting of the American Society of Clinical Oncology (ASCO)
4. Rosetta Genomics Signs Agreement With West Coast CLIA Certified Lab to Develop and Validate Tests Applying Companys MicroRNA Technology
5. Columbia University Medical Center and Rosetta Genomics Announce Columbia Universitys Submission of the First Cancer Diagnostic Test Based on Rosetta Genomics Proprietary MicroRNA Technology for Approval to the New York State Department of Health Clinica
6. Virogenomics, Inc. Awarded $2 Million National Institute of Standards and Technology (NIST) Advanced Technology Program Grant to Develop Integrated Diagnostic Biosensors
7. Harvard Medical School-Partners HealthCare Center for Genetics and Genomics Successfully Completes Evaluation of AutoGenomics 2C9-VKORC1 Panel to Assess Warfarin Sensitivity
8. Harvard Medical School-Partners HealthCare Center for Genetics and Genomics Successfully Completes Evaluation of AutoGenomics 2C9-VKORC1 Panel to Assess Warfarin Sensitivity
9. Grocery Manufacturers Association: Study Signals Progress in Battle Against Obesity
10. Annual Conference on Vaccine Research to Highlight Not Only Health Benefits But Also Economic Gains
11. Lixte Biotechnology Holdings Announces That Anti-Cancer Activity Against Glioblastoma in an Animal Model Was Reported at the Annual Meeting of the American Association of Cancer Research
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/20/2014)... -- Indianapolis interventional medical device maker NICO Corporation ... visualization leader Synaptive Medical announced today ... that they have joined forces to integrate their ... the first of its kind and will make ... BrainPath® interventional access technology and Synaptive,s BrightMatter™ real-time ...
(Date:10/20/2014)... 2014  ResMed (NYSE: RMD ) ... Exchange program, a comprehensive suite of software and ... other health care providers. ResMed ... patient information. It integrates valuable sleep and respiratory ... management platforms with customers, in-house or third-party electronic ...
(Date:10/20/2014)... BioNano Genomics announced today achievement of a major milestone ... at 30X depth, sufficient for a genome map, in 24 ... and demonstrated for the IrysChip TM V2, the high-throughput ... will be rolled out to BioNano,s collaborators and customers over ... at the American Society for Human Genetics (ASHG) 2014 ...
Breaking Medicine Technology:Indianapolis' NICO Corporation and Toronto's Synaptive Medical, Inc. Announce First-Ever Intervention-Visualization Partnership with Goal to Improve Standard of Care in Neurosurgery 2Indianapolis' NICO Corporation and Toronto's Synaptive Medical, Inc. Announce First-Ever Intervention-Visualization Partnership with Goal to Improve Standard of Care in Neurosurgery 3Indianapolis' NICO Corporation and Toronto's Synaptive Medical, Inc. Announce First-Ever Intervention-Visualization Partnership with Goal to Improve Standard of Care in Neurosurgery 4Indianapolis' NICO Corporation and Toronto's Synaptive Medical, Inc. Announce First-Ever Intervention-Visualization Partnership with Goal to Improve Standard of Care in Neurosurgery 5ResMed Launches ResMed Data Exchange 2BioNano Genomics Announces One Human : One Chip : One Day 2BioNano Genomics Announces One Human : One Chip : One Day 3
... Calif., Oct. 8 Varian Medical Systems (NYSE: ... fourth quarter of fiscal year 2010 following the close of ... will be followed by a teleconference available to all interested ... link to the conference call webcast will be available on ...
... 8 A growing number of healthcare providers ... to gain better control over non-file, off-contract spending, ... of Procurement Suite, healthcare decision-makers receive sound content, ... the procurement process, rather than after the fact. ...
Cached Medicine Technology:Varian Medical Systems Schedules Fourth Quarter FY2010 News Release and Conference Call 2Healthcare Providers Gain Control of Demand Channels With GHX Procurement Suite; 12 Percent Supply Spend Savings Achievable 2Healthcare Providers Gain Control of Demand Channels With GHX Procurement Suite; 12 Percent Supply Spend Savings Achievable 3
(Date:10/22/2014)... (PRWEB) October 22, 2014 On October ... Minds featuring skin diseases both fictional and real. ... (CEHMDF), a nonprofit organization committed to advocacy and philanthropy ... CBS will take the opportunity to impart truth and ... , There are many misconceptions about Morgellons ...
(Date:10/22/2014)... 2014 Isabel Healthcare will ... Professions (ASAHP) Conference on October 22-24 in Las Vegas, ... in a panel discussion on Technology in Health Professions ... provides a diagnostic decision support tool and clinical education ... of students and clinical learners. The Isabel tools help ...
(Date:10/22/2014)... HealthDay Reporter , TUESDAY, Oct. 21, 2014 ... cases in Dallas. But, mental health specialists say overblown fear ... Barack Obama on Friday appointed an Ebola "czar" to oversee ... Dallas nurses who cared for a Liberian man who died ... But the U.S. cases are miniscule in the context of ...
(Date:10/22/2014)... 2014 Shriners Hospitals for Children® and ... the current location of Shriners Hospitals for Children - ... from the University of Kentucky Albert B. Chandler Hospital. ... center, owned and operated by Shriners Hospitals for Children, ... children and their families well into the future. , ...
(Date:10/22/2014)... Angeles, California (PRWEB) October 22, 2014 Hay ... 2.0: Move Beyond Addiction and Upgrade Your Life (Paperback; $10.82) ... field of Yoga & Recovery. This book is meant ... thrive in a life of recovery. , Recovery 2.0 ... the 12 Steps; Recovery 2.0 is a guide for what ...
Breaking Medicine News(10 mins):Health News:CBS’ Criminal Minds takes aim at skin disease with Morgellons in the Mix 2Health News:CBS’ Criminal Minds takes aim at skin disease with Morgellons in the Mix 3Health News:Isabel Healthcare to Participate in The Association of Schools of Allied Health Professions (ASAHP) 2014 Conference 2Health News:Ebola Anxiety: A Bigger Threat Now Than the Virus Itself 2Health News:Ebola Anxiety: A Bigger Threat Now Than the Virus Itself 3Health News:Shriners Hospitals for Children - Lexington Announces Plan to Build New $47 Million Facility 2Health News:Shriners Hospitals for Children - Lexington Announces Plan to Build New $47 Million Facility 3Health News:Hay House Announces The Official Release of Recovery 2.0: Move Beyond Addiction and Upgrade Your Life 2Health News:Hay House Announces The Official Release of Recovery 2.0: Move Beyond Addiction and Upgrade Your Life 3
... Eden Medical Center a health affiliate with campuses in ... decision to call off its program to provide elective ... made available through the California Medical Assistance Commission. ... who will now be referred to various other hospitals ...
... AZD2171 which reduced the size and number of polyps in ... soon be used in humans with bowel cancer. , The ... Carcinogenesis, and Dr.Robert Goodlad, leader of the research team hopes that ... to treat polyps in humans thus preventing tumours. , Nearly ...
... smoking cessation therapy used to help reduce adverse events ... of death for smokers admitted to// the intensive care ... 2006, the 72nd annual international scientific assembly of the ... smokers admitted to the ICU who received nicotine replacement ...
... away with invasive breast reconstruction surgery, replaced by an ... suggest University of Pittsburgh researchers who are investigating the ... tissue. ,In animal models, the researchers hope ... that are seeded onto microscopic scaffold structures will enable ...
... alcohol beverages can play a role in a healthful ... //diseases, including coronary heart disease, diabetes, obesity, cognitive disorders ... presented papers at a recent conference on the role ... ,The conference, “Beer: To Your Health!” convened by ...
... research has unearthed substantial evidence to prove that smoking cigarettes ... to the health// of co passengers. If it is children ... researchers from Wellington School of Medicine. ,Traveling with ... can be compared with an evening spent in a smoky ...
Cached Medicine News:Health News:Smoking Cessation Therapy May be Harmful for ICU Patients 2Health News:Breast reconstruction may be possible with fat stem cells 2Health News:Daily Moderate Consumption of Beer May be Healthy 2
Surgitie&trade Single Use Ligating Loops without Delivery System with POLYSORB™....
ENDO STITCH™ Single Use Loading Units....
... Endo Stitch™ single use suturing device ... the placement of interrupted or running ... Stitch™ single use suturing device is ... 10mm short with the choice of ...
... Each ENDOKNOT™ consists of a 42" long suture ... is narrow at one end and scored on ... end and swaged to a ST-3 needle. The ... the scored end of the plastic tube. The ...
Medicine Products: