Navigation Links
Orion Genomics Enters Discovery Collaboration and License Agreement to Advance Personalized Diagnostics
Date:10/12/2009

ST. LOUIS, Oct. 12 /PRNewswire/ -- Orion Genomics today announced that it has entered into a multi-year collaboration and license agreement with the molecular diagnostics unit of Novartis Pharma AG. Under the collaboration, the parties seek to discover novel epigenetic biomarkers, and both parties have rights to independently develop and commercialize diagnostic products in their respective fields. Under the terms of the agreement, Orion Genomics also grants Novartis non-exclusive world-wide rights to its proprietary MethylScreen clinical assay technology. Financial terms were not disclosed.

"Epigenetic changes can play a key role in certain disease biology, and could lead to the development of important new diagnostic tools," said Nathan D. Lakey, President and CEO of Orion Genomics. "Ultimately, our collaboration with Novartis Molecular Diagnostics aims to support the development of innovative tests which we hope will provide physicians and patients with better information to guide treatment decisions."

The collaboration will leverage Orion Genomics' MethylScope® Technology to build high-resolution genome-wide DNA methylation maps for the discovery of epigenetic biomarkers in multiple disease fields. Novartis also obtains a non-exclusive license to MethylScreen® Technology, Orion's PCR-based clinical assay platform that quantitatively detects epigenetic biomarkers in patient samples. Under the agreement, Orion and Novartis intend to develop and commercialize promising diagnostic products that address various stages of disease. Resulting diagnostic tests could lead to advances in personalized medicine, potentially helping doctors optimize the treatment of patients.

"Science is revealing that epigenetics is a potent driver of disease biology and therapeutic response and a potential linchpin in the efforts to make personalized medicine a reality," said Howard McLeod, Professor of Medicine and Pharmacy and Director of the University of North Carolina Institute for Individualized Therapy. "As we consider how to optimize the use of the healthcare dollar, leveraging personalized medicine tools such as epigenetics to do a better job of matching individual patients with effective therapies will become ever more important."

Orion Genomics' MethylScope and MethylScreen technologies are used to discover and validate epigenetic biomarkers, which are changes to a layer of information written on top of the DNA molecule in the form of DNA methylation. DNA methylation controls whether or not a gene is turned on or off, also called gene-silencing. Epigenetic changes can be associated with disease risk, disease progression, and response to therapy.

About Orion Genomics

Orion Genomics, the Second Code Company, develops epigenetic research tools and molecular diagnostic products to fulfill the promise of personalized medicine. Orion's lead product is a simple blood-based test being developed to identify people at elevated risk for colorectal cancer. The company has active biomarker discovery programs in cancers of the bladder, breast, lung, ovaries and colon, and the company offers genomics services to the medical and agricultural and bio-fuels research communities. Orion Genomics is located in the Center for Emerging Technologies in St. Louis. For more information, visit the Orion Genomics website at http://www.oriongenomics.com.

SOURCE Orion Genomics


'/>"/>
SOURCE Orion Genomics
Copyright©2009 PR Newswire.
All rights reserved

Related medicine technology :

1. Orion Genomics Gains Exclusive Worldwide Rights to the IGF2 Gene for Colorectal Cancer Risk Testing Through Licensing Agreement With Johns Hopkins University
2. Orion Genomics Announces the Discovery of Novel Breast Cancer Biomarkers
3. Genome Quebec and Montreal Heart Institute Pharmacogenomics Centre Deploys Isilon IQ in Next Generation of Drug Development
4. Curemark CEO Presents at Epigenomics Conference
5. Juvenile Diabetes Research Foundation, The Genomics Institute of the Novartis Research Foundation Announce Innovative Diabetes Drug Discovery and Development Partnership
6. Sirius Genomics Announces New Collaboration with Assistance Publique-Hopitaux de Paris
7. First Jatropha Genome Completed by Synthetic Genomics Inc. and Asiatic Centre for Genome Technology
8. Clinical Genomics Continues Progress in Developing Biomarker Portfolio for Colorectal Cancer Testing
9. Prometheus and Rosetta Genomics Announce License and Collaboration Agreement
10. Rosetta Genomics Reports First Ever In-Vivo Efficacy Data for a Systemic MicroRNA Therapeutic for Liver Cancer
11. Rosetta Genomics Announces Commercial Availability of its First MicroRNA-Based Diagnostic Test; Will Host Teleconference to Discuss Launch of Future Tests
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/24/2017)... January 24, 2017 www.Financialbuzz.com ... industries in the United States as ... 2016. In addition, Proposition 64, the California Cannabis Legalization Initiative, ... against on November 8, 2016. This outcome means that individuals ... and to grow a certain amount of cannabis for personal ...
(Date:1/24/2017)... , Jan. 24, 2017   QR Pharma ... company developing novel therapies for the treatment of ... the appointment of four world-class key opinion leaders ... appointments join QR Pharma,s previous roster of impressive ... direction to support the development of the breakthrough ...
(Date:1/24/2017)... 2017 Mezzion has filed a suit for ... alleging that Dr. Reddy,s committed fraud relating to Dr. ... Administration (FDA) cGMP practices, and misrepresenting its compliance to ... to Mezzion that it was compliant with FDA regulations, ... suit also states that Dr. Reddy,s misconduct was the ...
Breaking Medicine Technology:
(Date:1/24/2017)... CA (PRWEB) , ... January 24, 2017 , ... Learn ... studies, work, athletics or even in relationships. Course offered by Dr. Carol Francis ... necessary due to limited seating and the many hands-on experiences. , Dr. ...
(Date:1/24/2017)... PA (PRWEB) , ... January 24, 2017 , ... ... advocacy company, announced today that its annual Solutions Series of webinars will start ... industry thought leaders discussing a number of current health and benefits topics, including ...
(Date:1/24/2017)... (PRWEB) , ... January 24, 2017 , ... Bellus Medical, ... company’s team of medical experts. In his new role Dr. Dobke will provide physician ... , Dr. Dobke is the Head of Plastic Surgery and Associate Professor of Surgery ...
(Date:1/24/2017)... ... January 24, 2017 , ... Providing solutions ... new report from the Frank Hawkins Kenan Institute of Private Enterprise ... academics and policy makers identified concrete solutions at the “What’s Next, America?” conference ...
(Date:1/24/2017)... , ... January 24, 2017 , ... The results from ... for everyone and particularly good news for prostate cancer patients: incidents of cancer is ... According to the report the cancer death rate has dropped from its peak of ...
Breaking Medicine News(10 mins):