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Optimization of Comparative Efficacy Trials
Date:9/19/2012

NEW YORK, Sept. 19, 2012 /PRNewswire/ -- Reportlinker.com announces that a new market research report is available in its catalogue:

Optimization of Comparative Efficacy Trials

http://www.reportlinker.com/p0968581/Optimization-of-Comparative-Efficacy-Trials.html#utm_source=prnewswire&utm_medium=pr&utm_campaign=Drug_Discovery_and_Development

Clinicians and patients want to be able to compare new drugs with those already available to inform evidence-based medicine, and reimbursement authorities require comparative data to support their decisions. This report discusses the optimization of comparative efficacy trials, with particular attention to the question of comparator selection.Understand the role that comparative efficacy plays in the evaluation of new drugs.Identify decision-making processes for guiding key choices in the design of pivotal comparative efficacy trials.Understand the importance of comparator selection and the consequences of later disagreements with external authorities.Review the factors that need to be considered in making a comparator selection.Assess the opportunity for gaining input from drug evaluation authorities.The choice of active control group for a comparative trial can be difficult due to variation in the standard of care across different geographic regions and changing medical practicesNumerous recent appraisals by the UK's National Institute for Health and Clinical Excellence (NICE) and Germany's Institut für Qualität und Wirtschaftlichkeit im Gesundheitswesen (IQWiG) have demonstrated the critical stance that is being rea
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