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Optimer Reports Fourth Quarter and Fiscal Year 2012 Financial Results
Date:2/28/2013

DIFICID net product sales.

DIFICID net product sales in the U.S. and Canada for the year and quarter ended December 31, 2012 were $62.4 million and $16.8 million, respectively.  We recognize product sales of DIFICID upon delivery of product to our wholesalers.  The increase in DIFICID net product sales in 2012 reflects higher demand for DIFICID, as well as a full year of sales.  DIFICID was launched in July 2011.

Contract revenue for the years ended December 31, 2012 and 2011 was $39.1 million and $122.7 million, respectively, a decrease of $83.6 million.  Contract revenue is generated from collaboration partners and includes up-front and milestone payments, royalties and product sales.  In 2011, contract revenue included a $69.2 million up-front payment from APEL and a $53.5 million milestone upon EMA approval of DIFICLIR™.
Contract revenue in 2012 included a $19.9 million up-front payment from Astellas Japan and a $12.6 million milestone payment from APEL in association with the first commercial sale of DIFICLIR in an APEL territory.  Contract revenues in 2012 also included inventory shipments to our collaboration partners and royalty income from APEL.

Research and development expense for the years ended December 31, 2012 and 2011 was $45.2 million and $43.1 million, respectively, an increase of $2.1 million.  The increase primarily was due to higher health economics and outcomes research and pharmacovigilance expenses.  We also incurred expenses related to our prophylaxis and pediatric clinical trials, which began in 2012.  The increase was partially offset by lower materials costs associated with DIFICID production prior to FDA approval in 2011.  Research and development expense for the quarters ending December 31, 2012 and 2011 was $11.9 million and $14.0 million, respectively, a decrease of $2.1 million. 

Selling, general and administrative expense
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SOURCE Optimer Pharmaceuticals, Inc.
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