Navigation Links
Optimer Pharmaceuticals Announces Combined Data From Fidaxomicin Phase 3 Trials for the Treatment of Clostridium difficile Infection (CDI) Presented at IDSA
Date:10/23/2010

4/518)

< 0.001

(6.7, 17.6)modified Intent-to-Treat
(mITT)Fidaxomicin
(200mg bid)Vancocin® capsules
(125mg qid)p-value95% Confidence IntervalClinical Cure87.9% (474/539 patients)

86.2% (488/566 patients)

NA

(-2.3, 5.7)Recurrence14.1% (67/474)

26.0% (127/488)

< 0.001

(-16.8, -6.8)Global Cure75.5% (407/539)

63.8% (361/566)

< 0.001

(6.3, 17.0)NA= Not Applicable (trial met non-inferiority endpoint)The Per Protocol (Microbiologically Evaluable) Population is the patient group with CDI confirmed by diarrhea with a positive toxin assay, met all inclusion/exclusion criteria, and received at least 3 days of therapy and were considered a failure or at least 8 days of therapy and were considered a cure.The Modified Intent-to-Treat Population is the patient group with CDI confirmed by diarrhea  with a positive toxin assay and received at least one dose of study medication."The combined data set of more than 1,100 patients show that fidaxomicin is statistically superior in preventing recurrences and achieving global cures compared to vancomycin.  Fidaxomicin as a single agent offers potential advantages over existing therapies," said Dr. Crook, Consultant Microbiology/Infectious Diseases and Professor of Infectious Diseases and Microbiology, Experimental Medicine Division, Nuffield Department of Clinical Medicine (NDM), University of Oxford.  

For a complete list of abstracts, please visit the Resources page on our website: www.optimerpharma.com

Fidaxomicin Clinical StudiesThe two fidaxomicin Phase 3 clinical studies were multi-center, randomized, double-blind trials, which enrolled a total of 1,164 adult subjects.  Subjects with confirmed CDI received either fidaxomicin (200 mg q12h) or Vancocin® (125 mg q6h), the only FDA approved product for the treatm
'/>"/>

SOURCE Optimer Pharmaceuticals, Inc.
Copyright©2010 PR Newswire.
All rights reserved

Page: 1 2 3 4 5

Related medicine technology :

1. Optimer Pharmaceuticals Receives Production Patent for Lead Product Candidate Fidaxomicin
2. Optimer Pharmaceuticals Presents Results From Fidaxomicin Phase 3 Study for the Treatment of Clostridium difficile Infection
3. Data From Optimers Second Phase 3 Study of Prulifloxacin Presented at Annual Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC)
4. Optimer Announces Presentation of Additional Data From Fidaxomicin Phase 3 Study for the Treatment of Clostridium Difficile Infection (CDI)
5. Optimer Pharmaceuticals to Present at the 21st Annual Piper Jaffray Health Care Conference
6. Optimer Pharmaceuticals to Present at the 28th Annual J.P. Morgan Healthcare Conference
7. Optimer Pharmaceuticals Fidaxomicin Marketing Authorization Application Accepted for Review by European Medicines Agency
8. Optimer Pharmaceuticals to Present at September 2010 Investor Conferences
9. Optimer Pharmaceuticals Announces Presentations of Additional Fidaxomicin Phase 3 Data at Upcoming ICAAC Annual Meeting
10. Auxilium Pharmaceuticals, Inc. Receives Clearance to Resume Clinical Trials for XIAFLEX(TM)
11. Vion Pharmaceuticals Completes Accrual of 85 Patients to its Pivotal Phase II Trial of Cloretazine(R) (VNP40101M) in Elderly AML
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/14/2014)... 2014  More than any other generation, Millennials born in ... -- but their eyes don,t. These mobile devices demand a ... the eye has not evolved to cope with them. The ... do comfortably often results in tired eyes, focusing problems, headaches ... Strain. Now ZEISS has invented a new type of lens ...
(Date:7/14/2014)... July 14, 2014  Today, ATS Labs, Inc. (ATS), ... acquired the assets of MicroTest Labs, Inc. (MTL) of ... MTL is the first step in the strategy of ... platform to support the medical device and biopharmaceutical industries. ... Accuratus Lab Services , a name that personifies the ...
(Date:7/14/2014)... , July 14, 2014  Mallinckrodt plc (NYSE: ... QCOR ) today announced that the registration statement on Form ... by Mallinckrodt plc on May 16, 2014 and amended on ... Mallinckrodt and Questcor that also constitutes a prospectus of Mallinckrodt, ... on Form S-4 is available on the SEC,s EDGAR system, ...
Breaking Medicine Technology:New Eyeglass Lens Helps Our Eyes Keep Up with our Digital Lives 2New Eyeglass Lens Helps Our Eyes Keep Up with our Digital Lives 3ATS Labs, Inc. Announces the Acquisition of MicroTest Labs, Inc. 2ATS Labs, Inc. Announces the Acquisition of MicroTest Labs, Inc. 3Mallinckrodt Pharmaceuticals And Questcor Pharmaceuticals Provide Update On Transaction 2Mallinckrodt Pharmaceuticals And Questcor Pharmaceuticals Provide Update On Transaction 3Mallinckrodt Pharmaceuticals And Questcor Pharmaceuticals Provide Update On Transaction 4Mallinckrodt Pharmaceuticals And Questcor Pharmaceuticals Provide Update On Transaction 5Mallinckrodt Pharmaceuticals And Questcor Pharmaceuticals Provide Update On Transaction 6Mallinckrodt Pharmaceuticals And Questcor Pharmaceuticals Provide Update On Transaction 7
... and women infected with HIV reduced the risk of ... of oral antiretroviral therapy (ART), according to findings from ... Prevention Trials Network (HPTN), a global partnership dedicated to ... and structural interventions. The study, known ...
... May 12, 2011 Alma Lasers Ltd., a ... aesthetic treatment devices, today announced the launch of ... for aesthetic fractional laser resurfacing. ... iPixelEr—each feature Alma,s roller-style technology which delivers fast, ...
Cached Medicine Technology:Initiation of Antiretroviral Treatment Protects Uninfected Sexual Partners from HIV Infection (HPTN Study 052) 2Initiation of Antiretroviral Treatment Protects Uninfected Sexual Partners from HIV Infection (HPTN Study 052) 3Initiation of Antiretroviral Treatment Protects Uninfected Sexual Partners from HIV Infection (HPTN Study 052) 4Initiation of Antiretroviral Treatment Protects Uninfected Sexual Partners from HIV Infection (HPTN Study 052) 5Alma Lasers Introduces the iPixel Fractional Ablative Technology 2
(Date:7/14/2014)... According to a recent study ... a connection between women with high levels of a ... doctors have theorized about the role stress plays in ... provide scientific support. , “Stress, if very significant, can ... Barmat, an OB/GYN who specializes in reproductive endocrinology and ...
(Date:7/14/2014)... Last month Bromell Agency officially launched the new ... more detailed information on how clients can protect and ... boats in the state of Louisiana. , The agency ... website in order to better educate clients on the ... the website, which is to display comprehensive insurance information ...
(Date:7/14/2014)... 14, 2014 There’s an old adage that ... The Lash Palette say the products offered in their ... , “You can reserve The Lash Palette for $40,” said ... Store . , Paris explained that the first 1,000 have ... 21. , She went on to point out that her ...
(Date:7/14/2014)... 2014 Seven promising startup companies ... problems have been accepted into the University ... (DHA). , The awardees were selected from ... process. They include Biomeme, Fitly, Life Patch, Curbside ... France) and Pulse InfoFrame (from Canada) —both of ...
(Date:7/14/2014)... 2014 Jordan Valley Medical Center is ... comprehensive cancer center set to open by the fall ... only hospital west of I-15 in the Salt Lake ... Additionally, Jordan Valley Medical Center has partnered with Elekta, ... planning systems for radiation therapy, radiosurgery and brachytherapy, to ...
Breaking Medicine News(10 mins):Health News:Abington Health Physician Addresses Link Between Stress and Infertility 2Health News:Abington Health Physician Addresses Link Between Stress and Infertility 3Health News:The Lash Palette Preorder Event Has Officially Begun 2Health News:Seven Healthcare Startups Selected to Participate in University City Science Center’s First Digital Health Accelerator 2Health News:Seven Healthcare Startups Selected to Participate in University City Science Center’s First Digital Health Accelerator 3Health News:Seven Healthcare Startups Selected to Participate in University City Science Center’s First Digital Health Accelerator 4Health News:Jordan Valley Medical Center Set to Break Ground with New $10 Million Cancer Center 2
... day to day life. Keeping fit costs hardly anything if ... a gym or health club,// you'll be familiar with high ... These items typically cost thousands of dollars and might be ... But you can get the same results practically for free, ...
... lasers help remove lines and wrinkled from age and ... can take its toll in later years in terms ... But, says Dr Arielle Kauvar, a dermatologist at New ... smoother, firmer appearance. ,These lasers score over ...
... of botulinum toxin eases hand spasticity among stroke survivors. Spasticity ... and it causes much disability,// because it interferes with activities ... botulinum toxin - a substance that relieves muscle tightness - ... large trial of botulinum toxin (also known as botox) in ...
... may be combined with tumor growth in mice. At ... or similar pain medications will lead to increased cancer ... further studies for managing cancer pain. ,Researchers ... of morphine, similar to doses given to cancer patients ...
... potency can be influenced by various reasons. Many advertisments ... impotence to the attention of thousands of people.// Impotence ... men are taking help, particularly as large segments of ... range from 12 million to 30 million men in ...
... An acid found naturally in the body can block the ... There is no cure for Huntington's disease (HD), which is ... But researchers at the University of Texas may be one ... with HD. ,The mice were treated with a ...
Cached Medicine News:Health News:Many factors influence sexual potency 2
... Cronin, Inc. is a ... Footwear, Orthopedic Softgoods, and ... Our products are of ... available in the USA ...
... ThumbFit™ reduces joint instability without disturbing ... remarkably comfortable and easy for users ... CHT and Robert V. Sypher Jr., ... in response to patients' complaints of ...
... the MP joint and the CMC joint of the ... both of the thumb joints. An excellent choice for ... who need maximum mobility for daily activities. Ideal for ... and for those with pain due to repetitive stress. ...
... molded from rigid plastic in a distinctive design ... comfort. The uniquely sculpted distal trim line ... maximum function of the hand. This is ... and sprains of the MCP joint, basal joint ...
Medicine Products: