Navigation Links
Optimer Pharmaceuticals, Inc. Announces Presentation at ECCMID of Post-Hoc Subgroup Analysis of DIFICID in Adult Cancer Patients Being Treated for Clostridium difficile-Associated Diarrhea (CDAD)
Date:3/30/2012

SAN DIEGO, March 30, 2012 /PRNewswire/ -- Optimer Pharmaceuticals, Inc. (NASDAQ: OPTR) announced the presentation of results from a post-hoc subgroup analysis of the company's two large Phase 3 trials which demonstrated that cancer patients with Clostridium difficile-associated diarrhea (CDAD) had higher clinical cure rates, better sustained response and lower recurrence when treated with DIFICID® (fidaxomicin) tablets compared to oral vancomycin. The data will be presented at the 22nd European Congress of Clinical Microbiology and Infectious Diseases (ECCMID) in London.

(Logo:  http://photos.prnewswire.com/prnh/20090413/LA97352LOGO)

The analysis included 153 patients with active cancer who were treated in the two DIFICID Phase 3 studies and who received 8 days or more of treatment with DIFICID or oral vancomycin. In the overall combined population, patients with cancer had significantly lower cure and sustained response rates than patients without cancer. DIFICID was five times more likely than vancomycin to produce a clinical response and three times more likely to lead to a sustained response, while patients treated with vancomycin had a 2.6 fold greater risk of experiencing recurrence. Specifically, DIFICID provided superior response compared to vancomycin across all clinical endpoints studied: clinical response (97.3% vs. 87.5%, 95% CI 1.07-23.98; p=0.041), sustained response (83.6% vs. 61.3%, 95% CI 1.50-6.91; p=0.003) and disease recurrence (14.1% vs. 30.0%, 95% CI 0.16-0.89; p=0.025). Furthermore, cancer patients who were treated with DIFICID in the clinical studies had similar cure, recurrence and sustained response rates as non-cancer patients who received the drug, while cancer patients treated with vancomycin tended to have poorer outcomes than non-cancer patients. The ov
'/>"/>

SOURCE Optimer Pharmaceuticals, Inc.
Copyright©2010 PR Newswire.
All rights reserved

Page: 1 2 3 4 5

Related medicine technology :

1. Optimer Reports Fourth Quarter and Fiscal Year 2011 Financial Results
2. Optimer Pharmaceuticals to Host Conference Call and Webcast to Discuss Fourth Quarter and FY 2011 Financial Results
3. Optimer Pharmaceuticals to Present at the 32nd Annual Cowen Health Care Conference
4. Optimer Pharmaceuticals Provides Update on DIFICID® (fidaxomicin) Tablets Launch
5. Optimer Pharmaceuticals to Present at the 30th Annual J.P. Morgan Healthcare Conference
6. Optimer Pharmaceuticals Reports Inducement Grants Under NASDAQ Listing Rule 5635(c)(4)
7. Optimer Pharmaceuticals to Present at BioCentury Newsmakers Conference
8. Optimer Pharmaceuticals and Astellas Receive Positive Opinion from CHMP for European Approval of DIFICID™
9. Optimer to Provide DIFICID™ Launch Update at Morgan Stanley Global Healthcare Conference
10. Optimer Pharmaceuticals DIFICID Featured in 11 Presentations at 51st ICAAC
11. Optimer Pharmaceuticals to Present at September 2011 Investor Conferences
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/22/2014)... 22, 2014   TRU-D SmartUVC LLC, producers ... robot, announced today that the General Services Administration has ... 2019.   This newly formed agreement will ... of government purchasers, including Department of Veteran Affairs and ... Security contacts purchasing solutions for the Ebola effort in ...
(Date:12/22/2014)... , Dec. 22, 2014  ConvaTec, a privately-held ... Moraviec has been appointed Interim Chief Executive Officer of ... Moraviec succeeds Ken Berger .  "The Board of ... in leading ConvaTec over the past three years," said ... of Directors.  "We are confident that the company is ...
(Date:12/22/2014)... , Dec. 22, 2014 Swedish Orphan ... today announced that the Committee for Medicinal Products for ... has adopted a positive opinion for the use of ... men with Peyronie,s disease with a palpable plaque and ... start of therapy. The use of Xiapex ...
Breaking Medicine Technology:TRU-D SmartUVC LLC Awarded General Services Administration Contract to Expand Government Customer Base 2ConvaTec Names Paul Moraviec Interim CEO Effective December 22, 2014 2Sobi's Xiapex receives positive opinion by CHMP for the treatment of Peyronie's disease 2Sobi's Xiapex receives positive opinion by CHMP for the treatment of Peyronie's disease 3Sobi's Xiapex receives positive opinion by CHMP for the treatment of Peyronie's disease 4Sobi's Xiapex receives positive opinion by CHMP for the treatment of Peyronie's disease 5Sobi's Xiapex receives positive opinion by CHMP for the treatment of Peyronie's disease 6
... his recent trip to India, President Obama cited ... including GE and Boeing, as part of the New Export Initiative. ... the US from selling goods and services in India. Over the ... certified pre-owned medical equipment to India as a direct result ...
... Upsher-Smith Laboratories, Inc. today announced the addition ... global Phase III clinical trial for USL255 (extended-release ... treatment of adult epilepsy patients with partial-onset seizures, ... and reduce fluctuations in topiramate blood levels observed ...
Cached Medicine Technology:Skelley Medical Working with White House and President Obama in India 2Upsher-Smith Laboratories Announces Initiation of Open-Label Extension Study of USL255 (Extended-Release Topiramate) for Adjunctive Treatment of Partial-Onset Epilepsy 2Upsher-Smith Laboratories Announces Initiation of Open-Label Extension Study of USL255 (Extended-Release Topiramate) for Adjunctive Treatment of Partial-Onset Epilepsy 3
(Date:12/24/2014)... Florida (PRWEB) December 24, 2014 The Healthy ... safer place to raise families. In-Vest USA ... who protect us – our first responders. Today, these two ... enforcement officers by providing them with body armor through In-Vest’s ... the tragic shootings that happened this past week in New ...
(Date:12/24/2014)... Verde Pointe Dental Associates 2014 Ugly Holiday ... years homemade Christmas sweater lit up, but this years overall ... is Tandy Wilson for the second year in a row. ... Kimmerling DDS. "She took pictures of the entire staff and ... , "Every year I enjoy stopping by the dental ...
(Date:12/24/2014)... 24, 2014 As 2014 draws to ... that before investing time and money into a new ... professional that specializes in tankless and eco-friendly products or ... their water heater in 2015 to research “green” and ... , Greenstar Home Services specializes in eco-friendly and ...
(Date:12/24/2014)... By Dennis Thompson ... -- There,s good news about the experimental Ebola vaccine that ... new research shows a precursor of that vaccine produced ... earlier version of the vaccine, when given to more than ... antibodies and white blood cells that could potentially protect a ...
(Date:12/24/2014)... Alan Mozes HealthDay Reporter TUESDAY, ... indoor tanning beds and booths, although this risky behavior remains popular ... reveals. In 2013, about 20 percent of high school girls ... form of indoor tanning at least once in the previous year, ... percent of girls and nearly 7 percent of boys who had ...
Breaking Medicine News(10 mins):Health News:The Healthy Home Company and In-Vest USA Team Up to Save the Lives of Law Enforcement 2Health News:Verde Pointe Dental Associates Announces the 2014 Ugly Sweater Holiday Contest Winner 2Health News:Greenstar Home Services Offers Tankless Water Heater Advice to Local Homeowners 2Health News:Early Study Offers Hope for an Ebola Vaccine 2Health News:Early Study Offers Hope for an Ebola Vaccine 3Health News:Early Study Offers Hope for an Ebola Vaccine 4Health News:Fewer U.S. Teens in Tanning Salons, Study Finds 2Health News:Fewer U.S. Teens in Tanning Salons, Study Finds 3
... many human beings. A new Mayo Clinic study reveals the ... definition of contact dermatitis is that it is a skin ... direct contact with an allergen. ,The ten allergens ... ,? Nickel (nickel sulfate hexahydrate ,? Gold (gold sodium ...
... data on men's health over the last two decades. The ... a semi annual survey.// Judging by the response, the Harvard ... on how men can maintain a satisfying sex life, as ... most prevalent illness in elderly men followed by chronic illnesses ...
... Mumbai were crippled as the striking doctors were determined to ... All the government hospitals in Mumbai suffered due to absence ... 15 government-managed hospitals in this bustling city of over 15 ... demanding better security while on the job after relatives of ...
... Cyriac Joseph has expressed the need for quality medical ... not leave any stone unturned to weed out black ... this is a matter of grave concern to the ... The educationists, professionals, governments and all the stakeholders in ...
... from Duke university Medical Center have established that ... influenced by a complex interplay between genetic and ... crucial role in determining the psychological and biological ... results of four such studies that examined the ...
... that the much dreaded bird flu virus may be carried across ... the potential of posing a serious health hazard, specifically in the ... bird flu viral strain. ,The exact mechanism of how ... if bird flu virus is found in birds in U.K, it ...
Cached Medicine News:Health News:Health Services Came To A Halt As Mumbai Doctors Strike Continues 2Health News:Genes And Environmental Factors Determine Stress Response 2
Pneumatic micro sagittal saw, 30k cpm, available with various hose connector styles....
... power line from MicroAire. Our new ... electric instruments, offering the ultimate in ... has always wanted with the security ... Power Master reciprocating saw, Available with ...
... The 7600 Oscillating Saw offers ... osteotomies, thanks to its 14.4V ... cutting head may be rotated ... in any plane and will ...
... Brasseler USAs Large Bone Power System ... offers new technological advancements. The truly innovative ... power pack, which is comprised of the ... handpiece contains only mechanical components, which provides ...
Medicine Products: