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OptiNose Receives Grant to Fund Nose-to-Brain Research in Autism Spectrum Disorders
Date:11/8/2012

YARDLEY, Pa., Nov. 8, 2012 /PRNewswire/ -- OptiNose US Inc., today announced that its Norwegian affiliate was awarded NOK 12.3 million (USD $2.1 million) by the Research Council of Norway to study its unique nasal drug delivery technology in the treatment of autism spectrum disorders (ASDs). The OptiNose project was one of 59 company projects selected among the nearly 200 applications submitted to the Research Council's program for User-Driven, Research-Based Innovation Research. OptiNose will use this research grant to investigate "nose-to-brain" transport of oxytocin via the patented OptiNose Bi-Directional™ delivery technology for the treatment of ASDs. Partners who have agreed to collaborate with OptiNose in the project include the Department of Psychiatry at Oslo University Hospital, SINTEF and Smerud Medical Research and Norwegian academic institutions. It is anticipated that the Department of Psychiatry at the University of Minnesota will also participate in the program.

"The opportunity to investigate nose-to-brain drug transport with the OptiNose technology in an effort to develop a new treatment for autism spectrum disorders is very exciting," said Per G. Djupesland, M.D., Ph.D, Chief Scientific Officer (CSO) of OptiNose. "Autism spectrum disorders are growing in prevalence and there are no drugs approved to treat the core symptoms which burden children, adults and families with these conditions. We hope to see significant benefits from delivering treatment with our innovative nasal technology."

The Research Council of Norway Program for Innovation (BIA)
The BIA (Norwegian title: Brukerstyrt innovasjonsarena) program, developed by the Norwegian government, is designed to stimulate research and development that will result in new products, processes or services across a wide range of diverse business sectors. A record-breaking number of grant applications submitted to the Research Council's BIA program has resulted in a total
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