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OptiNose Completes Series C-1 Financing
Date:8/4/2014

pon prior approaches to intranasal drug delivery. Available data, including two published Phase II trials, suggest that OPN-375 has the potential to be a breakthrough product that could be transformational in the treatment of serious chronic nasal inflammatory diseases like chronic rhinosinusitis with nasal polyps. A global late-phase clinical program for nasal polyps, comparable in scale to that required for a new molecular entity and enrolling over 1,500 patients, is underway. Enrollment is ongoing or completed in all planned trials. OptiNose is also working to ensure that other critical enablers of future OPN-375 product success, including a launch-ready supply chain and other appropriate pre-commercial efforts, are in place to bring the product to market immediately following regulatory review.

About OptiNose

OptiNose is a specialty pharmaceutical company built around a unique nasal delivery platform. The company is driven by an experienced, world-class team with expertise including drug and device development, product manufacturing and commercialization. OptiNose is focused on using its patented technology to identify and develop reduced-risk assets that create significant commercial value by offering meaningful new clinical benefits to patients and healthcare systems. The OptiNose closed-palate

Bi-Directional™ Breath Powered™ technology platform provides dramatically enhanced delivery of drug into the nasal cavity compared to current approaches. When used to deliver select medications for diseases where this type of delivery is important to targeting, efficacy or safety, this innovative technology platform can be a critical enabler for the development of valuable new products. OptiNose has an exciting pipeline of these assets for the treatment of diseases with significant unmet need. OptiNose was founded in 2000 and has corporate offices in Yardley, PA (USA), Oslo, Norway, a
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