Navigation Links
Onyx Pharmaceuticals to Acquire Proteolix, Inc.
Date:10/12/2009

EMERYVILLE, Calif., Oct. 12 /PRNewswire-FirstCall/ -- Onyx Pharmaceuticals, Inc. (Nasdaq: ONXX) today announced that it has signed a definitive agreement to acquire Proteolix, Inc., a privately held biopharmaceutical company focused on discovering and developing novel therapies that target the proteasome for the treatment of hematological malignancies and solid tumors. Proteolix's lead compound, carfilzomib, is a proteasome inhibitor currently in multiple clinical trials, including an advanced Phase 2b clinical trial for patients with relapsed and refractory multiple myeloma.

"Carfilzomib is a next generation product candidate with a proven and well-validated mechanism of action, strong efficacy signals, demonstrated tolerability and a potential accelerated approval pathway," said N. Anthony Coles, M.D., president and chief executive officer of Onyx. "This acquisition leverages Onyx's proven expertise in developing and commercializing Nexavar® and provides strategic expansion into the $16 billion hematological malignancies market. The transaction structure reflects our approach to growing our business in a disciplined fashion, including earnout payments contingent on specific approval-based events. In addition, our development plan is designed to maintain our ability to continue to grow operating cash flow in 2010 and beyond."

Under the terms of the transaction, Onyx will make a $276 million cash payment upon closing of the transaction. Additional payments include $40 million payable in 2010 based on the achievement of a development milestone and up to $535 million contingent upon the achievement of certain regulatory approvals for carfilzomib in the U.S. and Europe. Of the potential $535 million, a payment of $170 million is based upon the achievement of accelerated U.S. Food and Drug Administration approval. The t
'/>"/>

SOURCE Onyx Pharmaceuticals, Inc.
Copyright©2009 PR Newswire.
All rights reserved

Page: 1 2 3 4 5

Related medicine technology :

1. Auxilium Pharmaceuticals, Inc. Receives Clearance to Resume Clinical Trials for XIAFLEX(TM)
2. Vion Pharmaceuticals Completes Accrual of 85 Patients to its Pivotal Phase II Trial of Cloretazine(R) (VNP40101M) in Elderly AML
3. Solvay Pharmaceuticals, Inc. and Wyeth Pharmaceuticals Announce Receipt of an FDA Action Letter for Bifeprunox, an Investigational Treatment for Schizophrenia
4. Callisto Pharmaceuticals Opens Additional Sites for Phase II Clinical Trial of Atiprimod in Advanced Carcinoid Cancer Patients
5. WallSt.net (www.wallst.net) Updates the Investment Community Through an All-New Interview With RegeneRx Biopharmaceuticals CEO
6. Quark Pharmaceuticals, Inc. Presented Positive Preclinical Results of Systemic RNAi Compound for Acute Renal Failure (ARF)
7. Peregrine Pharmaceuticals Doses First Patient in Cotara(R) Phase II Brain Cancer Trial In India
8. Nabi Biopharmaceuticals Announces Second Quarter 2007 Financial Results
9. Access Pharmaceuticals Provides Update on Clinical Development Plan of ProLindac
10. Quark Pharmaceuticals Extends Research Agreement with State University of New York for Proprietary siRNA Compounds for Acute Hearing Loss
11. Acura Pharmaceuticals, Inc. Secures Financing to Fund Pivotal Phase III Clinical Trial for Lead Aversion(R) Technology Product Candidate
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/18/2014)... , September 19, 2014 ... ( http://www.researchandmarkets.com/research/qqjrnh/global_molecular ) has announced the addition ... 2014-2018" report to their offering. ... involves the study of chromosomes using molecular ... of genes and chromosomes. It plays a ...
(Date:9/18/2014)...  Low T Center endorses the recommendations of ... Hyattsville, Maryland earlier this week. The FDA ... population for testosterone therapy (TRT), as well as ... recent claims from studies that TRT affects cardiovascular ... do not provide convincing evidence that TRT is ...
(Date:9/18/2014)... KANSAS CITY, Kan. , Sept. 18, 2014 ... ), a pet therapeutics company focused on licensing, ... animals, today announced the full exercise of the ... common stock in connection with the company,s previously ... stock.  All of the shares are being offered ...
Breaking Medicine Technology:Global Molecular Cytogenetics Market 2014-2018: Key Vendors are Abbott, Affymetrix, Agilent Technologies, F. Hoffmann-La Roche, Illumina and PerkinElmer 2Global Molecular Cytogenetics Market 2014-2018: Key Vendors are Abbott, Affymetrix, Agilent Technologies, F. Hoffmann-La Roche, Illumina and PerkinElmer 3Low T Center Endorses The Joint FDA Committee Meeting on Testosterone 2Aratana Therapeutics, Inc. Announces Full Exercise of Underwriters' Option to Purchase Additional Shares 2
... VIEW, Calif., Dec. 21, 2010 MAP Pharmaceuticals, Inc. (Nasdaq: ... ™ open-label safety trial.  The Company has now completed ... (NDA) for LEVADEX and plans to submit an NDA in ... inhaled migraine therapy that has completed Phase 3 clinical development ...
... -- China Botanic Pharmaceutical Inc. (AMEX: CBP ... and distributor of botanical products, bio-pharmaceuticals and traditional Chinese ... considerable progress in its efforts to comply with the ... 404") for fiscal year 2010. As announced ...
Cached Medicine Technology:MAP Pharmaceuticals Announces Completion of LEVADEX™ Open-Label Safety Trial 2MAP Pharmaceuticals Announces Completion of LEVADEX™ Open-Label Safety Trial 3China Botanic Announces Progress on its SOX 404 Compliance Program 2China Botanic Announces Progress on its SOX 404 Compliance Program 3
(Date:9/19/2014)... September 19, 2014 September 1, 2014 ... will introduce its state-of-the-art, fiber based, Smart Private Network ... implementation begins in Tahlequah, Oklahoma, which is the capital ... connecting facilities within the Tahlequah area for the remainder ... educational institutions within the fourteen counties of the Cherokee ...
(Date:9/19/2014)... 19, 2014 AttorneyOne.com, a recognized authority on ... from the FDA on Potassium Chloride . , ... recalled one lot of Potassium Chloride Injection 10mEq ... cartons. Potassium Chloride, administered intravenously, is used to treat potassium ... on a labeling error on the shipping cartons in a ...
(Date:9/19/2014)... 2014 Mount Pleasant Retirement Village ... Health and Well-Being Coach Christi Hall to campus. , Hall’s ... brain tumors and gaining weight as a result of years ... and learning about nutrition. One year later she had lost ... her strength, endurance and cardio. , After joining the YMCA ...
(Date:9/19/2014)... Final Cut Pro X plugin and effects manufacturer, ... template for Apple's Final Cut Pro X . , ... FCPX users to create a professional themed video with ease ... Pixel Film Studios, "With 48 camera options and On-Screen controls, ... Theme." , Float features all of the tools needed ...
(Date:9/19/2014)... Washington, D.C. (PRWEB) September 19, 2014 ... in Madison County Circuit Court (case 14-L-1175), following a ... Carole Owen is suing DePuy Orthopaedics Inc. and ... product was defective. Flood Law Group, a nationally known ... and has been following developments in litigation involving defective ...
Breaking Medicine News(10 mins):Health News:The Cherokee Nation and RBSC sign a “Memorandum of Agreement” That Brings Smart Connect to the Cherokee Nation 2Health News:Baxter Recalls Potassium Chloride Injection: AttorneyOne Monitors and Keeps Consumers Informed 2Health News:Mount Pleasant Retirement Village Partners with Atrium Family YMCA 2Health News:Mount Pleasant Retirement Village Partners with Atrium Family YMCA 3Health News:Pixel Film Studios Releases Float Theme for Final Cut Pro X Users 2Health News:Flood Law Group Comments on Recent Hip Replacement Lawsuit 2
... released today by the Association for Psychological Science: , , ... 65; in 2000 that number had jumped to 12.6 percent; and ... in that category. , , Cognitive decline was long ... seen a surge of interest in activities and products touted to ...
... Arcadia Resources, Inc. (NYSE Amex: KAD ... and pharmacy services under the Arcadia HealthCare(SM) brand, has ... Co., as Vice President of DailyMed(TM) Pharmacy Operations , ... the Indianapolis pharmacy operations, manage system integration within DailyMed ...
... Region recognizes immediate, ... ... Center and CHRISTUS St. Vincent Medical Group in Santa Fe, New Mexico, through teamwork, focused ... in nine months. CHRISTUS Health began managing CHRISTUS St. Vincent in April 2008 and ...
... health communications company StayWell Custom Communications (SCC), a division ... Grocer magazine to publish the white paper ... the Economy" to spotlight the retail sector,s growing need ... , , The white paper is a ...
... to include " Oncology Therapeutic ... , , - Center will train pharmacists to specialize in ... 23 Medco Health Solutions, Inc. (NYSE: MHS ), joined ... at AllPoints at Anson will house the Medco Therapeutic Resource Center(R) ...
... diagnostics market is poised for expansion with segments such ... potential. Heightened efforts to generate awareness about diabetes and ... development. For instance, limited awareness about HbA1C tests is ... curtailed with more education about the test. , ...
Cached Medicine News:Health News:Major New Report Establishes Effective Methods of Enhancing and Preserving Brain Power as We Age 2Health News:Major New Report Establishes Effective Methods of Enhancing and Preserving Brain Power as We Age 3Health News:Arcadia HealthCare Names Former Walgreen's Executive Charles Goodall as Vice President of DailyMed(TM) Pharmacy Operations 2Health News:Arcadia HealthCare Names Former Walgreen's Executive Charles Goodall as Vice President of DailyMed(TM) Pharmacy Operations 3Health News:Arcadia HealthCare Names Former Walgreen's Executive Charles Goodall as Vice President of DailyMed(TM) Pharmacy Operations 4Health News:CHRISTUS Health New Mexico Region Focuses on Cost Management; Saves $1.8 Million 2Health News:CHRISTUS Health New Mexico Region Focuses on Cost Management; Saves $1.8 Million 3Health News:Pivotal White Paper Examines Retail Industry's Critical Role in Reengineering the Health Care System 2Health News:Pivotal White Paper Examines Retail Industry's Critical Role in Reengineering the Health Care System 3Health News:Medco's Advanced Pharmacy Adds 162 New Jobs for Total of 1,400 2Health News:Medco's Advanced Pharmacy Adds 162 New Jobs for Total of 1,400 3Health News:Frost & Sullivan: Self-Monitoring and POC Diabetes Tests Reveal Potential for Significant Growth, Boosting the European Diabetes Diagnostics Market 2Health News:Frost & Sullivan: Self-Monitoring and POC Diabetes Tests Reveal Potential for Significant Growth, Boosting the European Diabetes Diagnostics Market 3
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
Medicine Products: