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Onyx Pharmaceuticals Presents Interim Results of Phase 1b Carfilzomib Combination Trial
Date:6/4/2010

Forward-Looking Statements

This news release contains "forward-looking statements" of Onyx within the meaning of the federal securities laws.  These forward-looking statements include without limitation, statements regarding the progress and results of the clinical development, safety, regulatory processes, commercialization efforts or commercial potential of carfilzomib.  These statements are subject to risks and uncertainties that could cause actual results and events to differ materially from those anticipated, including risks related to the development and commercialization of pharmaceutical products.  Any statements contained in this press release that are not statements of historical fact may be deemed to be forward-looking statements.  Reference should be made to Onyx's Annual Report on Form 10-K for the year ended December 31, 2009, filed with the Securities and Exchange Commission under the heading "Risk Factors" and Onyx's Quarterly Reports on Form 10-Q for a more detailed description of such factors.  Readers are cautioned not to place undue reliance on these forward-looking statements that speak only as of the date of this release.  Onyx undertakes no obligation to update publicly any forward-looking statements to reflect new information, events, or circumstances after the date of this release except as required by law.  

(i)   Partial response is defined by > 50% reduction of serum M-protein and reduction in 24 hour urinary M-protein by > 90% or to < 200 mg per 24 hours, International Uniform Response Criteria for Multiple Myeloma Published in Leukemia (2006) 20:1467-1473) with an Erratum in Leukemia (2007)21:1134-1135

(ii)  National Cancer Institute, Surveillance Epidemiology and End Results, 2007 Facts and Figures


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SOURCE Onyx Pharmaceuticals, Inc.
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