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Onyx Pharmaceuticals Announces Data Presentations of Carfilzomib and ONX 0912 at 47th American Society of Clinical Oncology Annual Meeting
Date:5/18/2011

SOUTH SAN FRANCISCO, Calif., May 18, 2011 /PRNewswire/ -- Onyx Pharmaceuticals, Inc. (Nasdaq: ONXX) today announced the presentation of several studies evaluating carfilzomib, a selective, next-generation proteasome inhibitor, and ONX 0912, an oral proteasome inhibitor, in hematological cancers at the 47th American Society of Clinical Oncology (ASCO) Annual Meeting, June 3-7, 2011 in Chicago, IL.

"The data that will be presented at ASCO continue to support carfilzomib's potential as a new treatment option for patients with multiple myeloma," said Ted W. Love, M.D., Executive Vice President and Head of Research and Development and Technical Operations at Onyx Pharmaceuticals. "We are committed to bringing carfilzomib to patients as quickly as possible, and are on track to complete the submission of the carfilzomib New Drug Application (NDA) in the July to August timeframe for potential accelerated approval in the U.S."

Carfilzomib data highlights include:

Interim results from PX-171-006, a phase (Ph) II multicenter dose expansion study of carfilzomib (CFZ), lenalidomide (LEN), and low-dose dexamethasone (loDex) in relapsed and/or refractory multiple myeloma (R/R MM)

  • Dr. Michael Wang, Anderson Cancer Center
  • Saturday, June 4, 2011, 12:00 – 1:00 p.m., E354a
  • General Poster Session – Lymphoma and Plasma Cell Disorders
  • Abstract #8025

The effect of carfilzomib in patients (Pts) with bortezomib (BTZ)-naive relapsed or refractory multiple myeloma (MM): Updated results from the PX-171-004 study

  • Dr. Keith Stewart, Mayo Clinic
  • Saturday, June 4, 2011, 12:00 – 1:00 p.m., E354a
  • General Poster Session – Lymphoma and Plasma Cell Disorders
  • Abstract #8026

PX-171-003-A
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SOURCE Onyx Pharmaceuticals, Inc.
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