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One Year Data from the PREFER in AF Registry Show Significant Changes in Atrial Fibrillation (AF) Management in Europe and Implementation of Clinical Guidelines
Date:9/2/2014

reduction in AF patients receiving antiplatelet agents (APs),[2] further supporting adherence to the latest guidance.[3]

Helping physicians to make informed future therapeutic decisions based on real-life data, the PREFER in AF registry further reveals factors which may influence treatment satisfaction and patient complaints contributing to a treatment switch to NOACs (213 patients) compared to those stably treated on VKAs (2102 patients). These include mobility problems (13.3% vs. 7.3%), complaints around dose adjustment (9.8% vs. 5.4%), and discomfort with bruising or pain (8.5% vs. 5.1%). Anxiety and depression traits also appear to influence choice of treatment.[1]

Raffaele De Caterina, Professor of Cardiology and Director, University Cardiology Division G. D'Annunzio University, Chieti Ospedale Clinicizzato SS. Annunziata: "One year results from PREFER in AF come at a pivotal time for AF management in Europe. The increase in NOAC uptake demonstrates that guideline recommendations are being implemented in clinical practice. NOACs may offer potential benefits over traditionally used VKAs, which are associated with several limitations like regular blood tests, frequent dose adjustments, interaction with a variety of foods and other medications. Because of this NOACs have the potential to offer patients an improved quality of life."

PREFER in AF enrolled 7,243 AF patients  across 461 centres in seven European countries, and collected one year follow up data from 6,412 patients, providing real-life insights into the key challenges faced by patients in AF and their physicians.[1],[4] VKAs such as warfarin have traditionally been the mainstay of AF management, but can present significant challenges in clinical pract
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SOURCE Daiichi Sankyo Europe GmbH
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