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One-Year Data From Global Atrial Fibrillation (AF) Registry Show Antithrombotic Agents Not Optimally Used to Prevent Stroke
Date:9/3/2013

Ps, was lower in patients with new AF (52.1%) vs. permanent AF (61.0%)
  • Stroke/systemic embolism risk was 47% increased in patients with permanent vs. new AF, though this difference was not statistically significant (HR 1.47, p=0.36)
  • New AF patients were slightly younger in age

  • Underutilisation of anticoagulants among a sizeable proportion of AF patients undergoing direct current conversion (DCC+) – a technique to get the heart into a normal sinus rhythm –despite guidelines recommending their use for stroke prevention
    • Few patients – 11.1% (n=614) patients – in the registry underwent DCC within four months of diagnosis, even though they were newly diagnosed with AF
    • Patients undergoing DCC were more likely to receive VKA therapy than patients not undergoing the procedure.  However, 6.9% of DCC+ patients received no antithrombotic therapy and 12.5% received only AP
    • Outcomes of all-cause death, stroke/SE or major bleed at 1 year did not differ between groups
  • About GARFIELD
    The GARFIELD Registry is an observational, multicentre, international prospective study of men and women with newly diagnosed AF and one or more additional risk factors for stroke.  It will prospectively follow 50,000 newly-diagnosed AF patients from at least 1,000 centres in 50 countries in the Americas, Eastern and Western Europe, Asia, Africa and Australia.

    GARFIELD is the largest prospective registry of patients with AF at risk of stroke. It seeks to describe the real-life burden of this disease, and provide insights into the impact of thromboembolic and bleeding complications seen in this patient population.  It will provide a better understanding of antithrombotic treatment patterns and potential opp
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    SOURCE Thrombosis Research Institute
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