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One-Year Data From Global Atrial Fibrillation (AF) Registry Show Antithrombotic Agents Not Optimally Used to Prevent Stroke
Date:9/3/2013

AMSTERDAM, Sept. 3, 2013 /PRNewswire/ -- One-year outcomes data from the first cohort of the Global Anticoagulant Registry in the FIELD (GARFIELD), an innovative, independent academic research initiative, provide insights into the elevated stroke risk among subpopulations of patients with atrial fibrillation (AF).  The findings, from eight abstracts presented this week at the ESC Congress 2013, collectively show that anticoagulant therapy – which is known to significantly lower stroke risk in AF patients – is consistently under-utilised among those at-risk AF patients.

GARFIELD is led by an international steering committee under the auspices of the Thrombosis Research Institute (TRI), London. It is an international, observational, multicentre, prospective study designed to understand the global burden of AF, a common condition in which the two upper chambers of the heart (the atria) quiver rather than beat rhythmically and can lead to life-threatening complications, including stroke. Up to 2% of the population has AF.1 Despite the availability of highly effective preventive treatments, AF-related stroke remains a major and increasing clinical and societal burden.

"These 1-year data from GARFIELD illustrate that evidence-based stroke prevention guidelines are not always followed in everyday clinical practice," said Professor The Lord Ajay Kakkar, Professor of Surgery at University College London and Director of the TRI, London UK . "Taken together, these new findings re-emphasize what has been observed in clinical trials regarding stroke risk in AF patients.  The research suggests there are opportunities to improve patient outcomes through more consistent application of best practice and adoption of the many innovative therapies to prevent stroke in high-risk AF patients."

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SOURCE Thrombosis Research Institute
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