Navigation Links
Onconome Announces Results Of Blood Test For Colorectal Cancer; Further Trials Underway
Date:9/14/2012

REDMOND, Wash., Sept 14, 2012 /PRNewswire/ -- Onconome, Inc. today reported the results of studies on 431 patients based upon the blood test it has developed to determine an individual's probability of having colorectal cancer (CRC). The results of the studies have been published in the September issue of the "American Journal of Cancer Research" and demonstrate that Onconome's test is highly sensitive (93.75%) and specific (82.89%) to CRC and has a Negative Predictive Value of 99.9775% (NPV), meaning that a negative test result indicates an extremely low probability of a given patient having CRC. Onconome also reported that two additional clinical trials are now underway at three independent sites to further validate the test's efficacy as a CRC pre-screening tool.

The first of these trials (ONC04) is designed to evaluate blood samples from subjects who are 50 to 80 years old and therefore considered to be at elevated risk of CRC and who are scheduled for colonoscopy. Their samples will then be compared to their colonoscopy results to validate the test's sensitivity, specificity and NPV. The second trial (ONC05) includes patients who have already been diagnosed with CRC or pre-cancerous adenomas via colonoscopy or sigmoidoscopy and are scheduled for surgery. The endpoint of this trial is to establish the test's efficacy in detecting dangerous pre-cancerous conditions in the colon. Both trials are expected to be completed in 2013.

"It's an established fact that nearly half of adults age 50 or older have not had a colonoscopy in the past ten years and that relatively few use fecal occult blood test home kits," said Ray Cairncross, chief executive officer of Onconome. "A simple blood test which addresses these low compliance rates and provides both patients and their clinicians with an accurate assessment of an individual's risk of CRC would be an important tool in deciding whether to have a colonoscopy or sigmoidoscopy."

Onconome is a privately held clinical-stage company committed to the discovery and development of products focused on the early detection of colorectal cancer. See www.onconome.com.


'/>"/>
SOURCE Onconome, Inc.
Copyright©2012 PR Newswire.
All rights reserved

Related medicine technology :

1. Valeant Pharmaceuticals Announces Management Change
2. Neuralstem Announces Proposed Public Offering
3. PPCE Announces Strategic Partnership With ECLINSO AG
4. Agendia Announces Five Studies in Breast Cancer for Presentation at the American Society of Clinical Oncology 2012 Breast Cancer Symposium
5. Boehringer Ingelheim announces afatinib expanded access program (EAP) for patients with EGFR mutation-positive advanced NSCLC
6. Soligenix Announces Issuance of US Patent for Topically Active Steroids to Treat Inflammatory Gastrointestinal Disorders
7. Henry Schein Announces New $500 Million Credit Facility
8. BioDelivery Sciences Announces Positive Results of Pivotal Pharmacokinetic Study Comparing BEMA Buprenorphine/Naloxone (BNX) to Suboxone
9. Biodel Announces Phase 2 Clinical Trial Initiation Of Ultra-Rapid-Acting Insulin Candidate BIOD-123
10. Simcere Pharmaceutical Group Announces Appointment of New Chief Executive Officer
11. Edison Pharmaceuticals Announces Positive Results of EPI-743 Phase 2A Leigh Syndrome Clinical Trial
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/24/2016)... 24, 2016 ... the addition of the " Global Markets for ... This report focuses on ... updated review, including its applications in various applications. The ... which includes three main industries: pharmaceutical and biotechnology, food ...
(Date:6/24/2016)... 2016 Research and Markets has announced ... Diagnostic Tests" report to their offering. ... The World Market for Companion Diagnostics covers ... Market analysis in the report includes the following: ... Diagnostic Kits) by Region (N. America, EU, ROW), 2015-2020 ...
(Date:6/23/2016)... HOUSTON , June 23, 2016  MedSource ... platform as its e-clinical software solution of choice.  ... the best possible value to their clients by ... nowEDC.  The preferred relationship establishes nowEDC as the ... pricing for MedSource,s full-service clients.  "nowEDC has long ...
Breaking Medicine Technology:
(Date:6/25/2016)... ... ... On Friday, June 10, Van Mitchell, Secretary of the Maryland Department of Health and ... their exemplary accomplishments in worksite health promotion. , The Wellness at Work Awards took ... the BWI Marriott in Linthicum Heights. iHire was one of 42 businesses to receive ...
(Date:6/24/2016)... ... ... June 19, 2016 is World Sickle Cell Observance Day. In an effort ... holistic treatments, Serenity Recovery Center of Marne, Michigan, has issued a pain ... Disease (SCD) is a disorder of the red blood cells, which can cause episodes ...
(Date:6/24/2016)... ... June 24, 2016 , ... ... for accelerated orthodontic treatment. Dr. Cheng has extensive experience with all areas of ... AcceleDent, and accelerated osteogenic orthodontics. , Micro-osteoperforation is a revolutionary adjunct to ...
(Date:6/24/2016)... ... 24, 2016 , ... EB Medicine presented its first-ever “Issue ... conference in Ponte Vedra Beach, FL. The awards honor the outstanding work of ... and Pediatric Emergency Medicine Practice. , “With this award, we recognize the ...
(Date:6/24/2016)... ... , ... National recruitment firm Slone Partners is pleased to announce ... experience, as Vice President of North American Capital Sales at HTG Molecular . ... sales team in the commercialization of the HTG EdgeSeq system and associated reagents in ...
Breaking Medicine News(10 mins):